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dimercaprol and Schistosomiasis

dimercaprol has been researched along with Schistosomiasis in 5 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Schistosomiasis: Infection with flukes (trematodes) of the genus SCHISTOSOMA. Three species produce the most frequent clinical diseases: SCHISTOSOMA HAEMATOBIUM (endemic in Africa and the Middle East), SCHISTOSOMA MANSONI (in Egypt, northern and southern Africa, some West Indies islands, northern 2/3 of South America), and SCHISTOSOMA JAPONICUM (in Japan, China, the Philippines, Celebes, Thailand, Laos). S. mansoni is often seen in Puerto Ricans living in the United States.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
OZAWA, K1
HSIEH, YY1
CHUE, YC1
HUANG, CH1
YANG, IT1
CHOW, CT1
KYI, ZY1
SPINGARN, CL1
EDELMAN, MH1
Kelada, FS1
Abdel-Tawab, GA1
Moustafa, MH1
Konbar, AA1
Khayyal, MT1

Other Studies

5 other studies available for dimercaprol and Schistosomiasis

ArticleYear
Studies on the therapy of schistosomiasis japonica. 2. On the Sb concentration in blood and the Sb distribution in organs during the intensive treatments of goats and at the Sb poisoned death of rabbits and on the effects of Bal and hypo and Sb antidote
    The Tohoku journal of experimental medicine, 1956, Dec-25, Volume: 65, Issue:1

    Topics: Animals; Antidotes; Antimony; Dimercaprol; Goats; Rabbits; Schistosomiasis; Schistosomiasis japonica

1956
Chemotherapeutic studies on schistosomiasis. IV. Some aryl ethers of dimercaptopropanol and their antimony mercaptides.
    Scientia Sinica, 1958, Volume: 7, Issue:5

    Topics: Antimony; Dimercaprol; Ethers; Schistosomiasis

1958
Observations on the treatment of schistosomiasis mansoni with fuadin.
    Annals of internal medicine, 1955, Volume: 42, Issue:6

    Topics: Antimony; Benzenesulfonates; Dimercaprol; Humans; Organometallic Compounds; Schistosomiasis; Schisto

1955
Comparative studies on the in vivo effects of tartar emetic, vitamin B 6 , and the chelating agent 2,3-dimercaptopropanol (BAL) on the functional capacity of the tryptophan-niacin pathway in patients with schistosomiasis.
    Metabolism: clinical and experimental, 1972, Volume: 21, Issue:12

    Topics: Acetates; Adolescent; Aminohippuric Acids; Antimony; Child; Dimercaprol; Emetics; Glucuronates; Huma

1972
Treatment of intestinal bilharziasis with antimonials: the possible use of dimercaprol as an adjuvant to therapy.
    Bulletin of the World Health Organization, 1965, Volume: 33, Issue:4

    Topics: Animals; Antimony; Dimercaprol; Mice; Schistosomiasis

1965