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dimercaprol and Respiratory Insufficiency

dimercaprol has been researched along with Respiratory Insufficiency in 2 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Respiratory Insufficiency: Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"All four suffered respiratory failure and subsequent death despite chelation therapy with dimercaprol."1.28Respiratory failure and death following acute inhalation of mercury vapor. A clinical and histologic perspective. ( Boyes, RJ; Eichenhorn, MS; Gottlieb, CA; Guerrero-Betancourt, D; Rowens, B, 1991)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greenberg, C1
Davies, S1
McGowan, T1
Schorer, A1
Drage, C1
Rowens, B1
Guerrero-Betancourt, D1
Gottlieb, CA1
Boyes, RJ1
Eichenhorn, MS1

Other Studies

2 other studies available for dimercaprol and Respiratory Insufficiency

ArticleYear
Acute respiratory failure following severe arsenic poisoning.
    Chest, 1979, Volume: 76, Issue:5

    Topics: Arsenic Poisoning; Dimercaprol; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Psych

1979
Respiratory failure and death following acute inhalation of mercury vapor. A clinical and histologic perspective.
    Chest, 1991, Volume: 99, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Dimercaprol; Female; Humans; Kidney; Lung; Male; Mercury Poisoning;

1991