dimercaprol has been researched along with Renal Insufficiency in 7 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
Excerpt | Relevance | Reference |
---|---|---|
"Inorganic mercury poisoning is uncommon, but when it occurs it can result in severe, life threatening features and acute renal failure." | 1.36 | Accidental inorganic mercury chloride poisoning in a 2-year old child. ( Khadwal, A; Kumar, R; Singhi, S; Verma, S, 2010) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (57.14) | 18.7374 |
1990's | 1 (14.29) | 18.2507 |
2000's | 1 (14.29) | 29.6817 |
2010's | 1 (14.29) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Cameron, GR | 1 |
Burgess, F | 1 |
Trenwith, VS | 1 |
Verma, S | 1 |
Kumar, R | 1 |
Khadwal, A | 1 |
Singhi, S | 1 |
SANCHEZ-SICILIA, L | 1 |
SETO, DS | 1 |
NAKAMOTO, S | 1 |
KOLFF, WJ | 1 |
SITBON, A | 1 |
VALEK, A | 1 |
Hantson, P | 1 |
Lievens, M | 1 |
Mahieu, P | 1 |
Kamijo, Y | 1 |
Soma, K | 1 |
Yosimura, K | 1 |
Ohwada, T | 1 |
7 other studies available for dimercaprol and Renal Insufficiency
Article | Year |
---|---|
The possibility of toxic effects from 2:3-dimercaptopropanol in conditions of impaired renal or hepatic function.
Topics: Dimercaprol; Hepatic Insufficiency; Humans; Renal Insufficiency; Sulfhydryl Compounds | 1947 |
Accidental inorganic mercury chloride poisoning in a 2-year old child.
Topics: Chelating Agents; Child, Preschool; Dimercaprol; Humans; Male; Mercuric Chloride; Poisoning; Renal I | 2010 |
ACUTE MERCURIAL INTOXICATION TREATED BY HEMODIALYSIS.
Topics: Acute Kidney Injury; Dimercaprol; Infusions, Parenteral; Kidney; Kidneys, Artificial; Mercury Poison | 1963 |
[RENAL INVOLVEMENT DURING ACUTE POISONINGS].
Topics: Acute Kidney Injury; Dimercaprol; Kidney; Kidneys, Artificial; Poisoning; Renal Insufficiency; Thiom | 1964 |
ACUTE RENAL INSUFFICIENCY IN INTOXICATIONS WITH MERCURY COMPOUNDS. II. TREATMENT AND PROGNOSIS.
Topics: Acute Kidney Injury; Antidotes; Anuria; Dimercaprol; Gastric Lavage; Kidneys, Artificial; Mercury Co | 1965 |
Accidental ingestion of a zinc and copper sulfate preparation.
Topics: Aged; Aged, 80 and over; Cardiovascular System; Chelating Agents; Copper Sulfate; Digestive System; | 1996 |
Acute mercuric chloride poisoning: effect of co-ingested milk on outcome and continued hyperamylasemia.
Topics: Administration, Oral; Aged; Aged, 80 and over; Animals; Binding Sites; Chelating Agents; Dimercaprol | 2001 |