Page last updated: 2024-10-26

dimercaprol and Purpura, Thrombopenic

dimercaprol has been researched along with Purpura, Thrombopenic in 8 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DE CORDOVA CASTRO, A1
PENALVER BALLINA, R1
SCHRUMPF, A1
WATSON, EM1
THOMPSON, M1
SINCLAIR, RJ1
DUTHIE, JJ1
NIEPEL, GA1
HONKAPOHJA, H1
Samara, AM1
Fernandes, SR1
Saphir, JR1
Ney, RG1

Other Studies

8 other studies available for dimercaprol and Purpura, Thrombopenic

ArticleYear
A case of arsical thrombocytopenic purpura treated with BAL.
    Boletin. Sociedad Cubana de Dermatologia y Sifilografia, 1948, Volume: 5, Issue:1

    Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Purpura; Purpura, Thrombocytopenic

1948
BAL therapy of thrombopenic purpura after arsphenamine treatment.
    Journal of the American Medical Association, 1947, Dec-27, Volume: 135, Issue:17

    Topics: Animals; Arsphenamine; Dimercaprol; Gastropoda; Humans; Purpura; Purpura, Thrombocytopenic

1947
The haematopathological complications of gold therapy: effects of splenectomy and bal.
    Canadian Medical Association journal, 1953, Volume: 69, Issue:1

    Topics: Anemia; Anemia, Aplastic; Arthritis; Arthritis, Rheumatoid; Dimercaprol; Gold; Humans; Purpura; Purp

1953
Thrombocytopenic purpura after administration of gold; comparison of treatment with dimercaprol, A.C.T.H., and cortisone.
    British medical journal, 1954, Apr-17, Volume: 1, Issue:4867

    Topics: Adrenocorticotropic Hormone; Arthritis; Arthritis, Rheumatoid; Cortisone; Dimercaprol; Gold; Purpura

1954
[Case of thrombopenic purpura following myochrisine treated with BAL].
    Bratislavske lekarske listy, 1951, Volume: 31, Issue:5-6

    Topics: Dimercaprol; Gold; Humans; Purpura; Purpura, Thrombocytopenic; Thrombocytopenia

1951
Treatment with BAL of a case of thrombocytopenic purpura.
    Annales medicinae internae Fenniae, 1949, Volume: 38, Issue:1

    Topics: Dimercaprol; IgA Vasculitis; Purpura; Purpura, Thrombocytopenic

1949
Dimercaprol in the treatment of thrombocytopenia purpura induced by gold salts.
    The Journal of rheumatology, 1985, Volume: 12, Issue:1

    Topics: Adult; Dimercaprol; Female; Gold; Humans; Middle Aged; Purpura, Thrombocytopenic

1985
Delayed thrombocytopenic purpura after diminutive gold therapy.
    JAMA, 1966, Feb-28, Volume: 195, Issue:9

    Topics: Dimercaprol; Gold; Humans; Male; Middle Aged; Purpura, Thrombocytopenic; Urine

1966