dimercaprol has been researched along with Proteinuria in 4 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One hundred sixty-two consecutive patients with rheumatoid arthritis (RA) were studied for possible association between HLA antigens, particularly DR antigens, and disease characteristics and adverse reactions to gold or D-penicillamine treatment." | 3.67 | A systematic survey of HLA-A,B,C and D antigens and drug toxicity in rheumatoid arthritis. ( Dequeker, J; Van Wanghe, P; Verdickt, W, 1984) |
| " Seven groups of adult male rats were given a single sc toxic dose of HgCl2 (0." | 1.30 | Comparison of the effectiveness of 2,3-dimercaptopropanol (BAL) and meso-2,3-dimercaptosuccinic acid (DMSA) as protective agents against mercuric chloride-induced nephrotoxicity in rats. ( Bellés, M; de la Torre, A; Domingo, JL; Llobet, JM; Mayayo, E, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Devlin, HB | 1 |
| Sudlow, M | 1 |
| Dequeker, J | 1 |
| Van Wanghe, P | 1 |
| Verdickt, W | 1 |
| de la Torre, A | 1 |
| Bellés, M | 1 |
| Llobet, JM | 1 |
| Mayayo, E | 1 |
| Domingo, JL | 1 |
| Damrau, J | 1 |
4 other studies available for dimercaprol and Proteinuria
| Article | Year |
|---|---|
Peripheral mercury embolization occurring during arterial blood sampling.
Topics: Adult; Blood Specimen Collection; Dimercaprol; Humans; Leukopenia; Male; Mercury; Mercury Poisoning; | 1967 |
A systematic survey of HLA-A,B,C and D antigens and drug toxicity in rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Cytotoxicity Tests, Immunologic; Dermatitis; Dimerca | 1984 |
Comparison of the effectiveness of 2,3-dimercaptopropanol (BAL) and meso-2,3-dimercaptosuccinic acid (DMSA) as protective agents against mercuric chloride-induced nephrotoxicity in rats.
Topics: Animals; Antidotes; Chelating Agents; Creatinine; Dimercaprol; Kidney; Male; Mercuric Chloride; Merc | 1998 |
[Treatment of mercury-induced organ damage].
Topics: Acute Kidney Injury; Adult; Dimercaprol; Drug Therapy, Combination; Humans; Indomethacin; Kidney Fun | 1990 |