dimercaprol has been researched along with Prosthesis Durability in 2 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These cobalt ions can result in local toxic effects-including peri-implant toxicity, aseptic loosening, and pseudotumor-as well as systemic toxic effects-including neurological, cardiovascular, and endocrine disorders." | 1.91 | Hyaluronic acid-British anti-Lewisite as a safer chelation therapy for the treatment of arthroplasty-related metallosis. ( Arnold, AM; Esdaille, J; Holt, BD; Kan, HM; Laurencin, CT; Laurencin, S; Nair, LS; Schmidt, SJ; Shah, S; Sydlik, SA; Ude, CC; Wolf, ME, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ude, CC | 1 |
| Schmidt, SJ | 1 |
| Laurencin, S | 1 |
| Shah, S | 1 |
| Esdaille, J | 1 |
| Kan, HM | 1 |
| Holt, BD | 1 |
| Arnold, AM | 1 |
| Wolf, ME | 1 |
| Nair, LS | 1 |
| Sydlik, SA | 1 |
| Laurencin, CT | 1 |
| Zhang, H | 1 |
| Tang, J | 1 |
| Meng, X | 1 |
| Tsang, J | 1 |
| Tsang, TK | 1 |
2 other studies available for dimercaprol and Prosthesis Durability
| Article | Year |
|---|---|
Hyaluronic acid-British anti-Lewisite as a safer chelation therapy for the treatment of arthroplasty-related metallosis.
Topics: Arthroplasty, Replacement, Hip; Chelating Agents; Chelation Therapy; Cobalt; Dimercaprol; Hip Prosth | 2023 |
Inhibition of bacterial adherence on the surface of stents and bacterial growth in bile by bismuth dimercaprol.
Topics: Animals; Anti-Bacterial Agents; Bacterial Adhesion; Bacterial Infections; Bile; Biofilms; Bismuth; D | 2005 |