Page last updated: 2024-10-26

dimercaprol and Prosthesis Durability

dimercaprol has been researched along with Prosthesis Durability in 2 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Research Excerpts

ExcerptRelevanceReference
" These cobalt ions can result in local toxic effects-including peri-implant toxicity, aseptic loosening, and pseudotumor-as well as systemic toxic effects-including neurological, cardiovascular, and endocrine disorders."1.91Hyaluronic acid-British anti-Lewisite as a safer chelation therapy for the treatment of arthroplasty-related metallosis. ( Arnold, AM; Esdaille, J; Holt, BD; Kan, HM; Laurencin, CT; Laurencin, S; Nair, LS; Schmidt, SJ; Shah, S; Sydlik, SA; Ude, CC; Wolf, ME, 2023)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Ude, CC1
Schmidt, SJ1
Laurencin, S1
Shah, S1
Esdaille, J1
Kan, HM1
Holt, BD1
Arnold, AM1
Wolf, ME1
Nair, LS1
Sydlik, SA1
Laurencin, CT1
Zhang, H1
Tang, J1
Meng, X1
Tsang, J1
Tsang, TK1

Other Studies

2 other studies available for dimercaprol and Prosthesis Durability

ArticleYear
Hyaluronic acid-British anti-Lewisite as a safer chelation therapy for the treatment of arthroplasty-related metallosis.
    Proceedings of the National Academy of Sciences of the United States of America, 2023, Nov-07, Volume: 120, Issue:45

    Topics: Arthroplasty, Replacement, Hip; Chelating Agents; Chelation Therapy; Cobalt; Dimercaprol; Hip Prosth

2023
Inhibition of bacterial adherence on the surface of stents and bacterial growth in bile by bismuth dimercaprol.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Bacterial Adhesion; Bacterial Infections; Bile; Biofilms; Bismuth; D

2005