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dimercaprol and Porphyria

dimercaprol has been researched along with Porphyria in 17 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Research

Studies (17)

Timeframe	Studies, this research(%)	All Research%
pre-1990	17 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
SCHRUMPF, A	1
PETERS, HA	5
PAUL, KG	1
THYRESSON, N	1
WOODS, S	1
EICHMAN, PL	2
REESE, HH	2
GULBRANDSEN, R	1
WIGMOSTAD, K	1
DOGRAMACI, I	1
CORNIL, A	1
THYS, O	1
DURET, RL	1
GOULON, M	1
MARGAIRAZ, A	1
NOUAILHAT, F	1
McCABE, ES	1
PAINTER, JT	1
MORROW, EJ	1
REDEKER, AG	1
STERLING, RE	1
ARCHER, B	1
Trux, F	1
Grossmann, K	1
Giegler, I	1
Czarnecki, J	1
Kawiak, W	1
Nowakowski, A	1
Soyka, D	1

Reviews

2 reviews available for dimercaprol and Porphyria

Article	Year
PORPHYRIAS AND PORPHYRIN METABOLISM, WITH SPECIAL REFERENCE TO PORPHYRIA IN CHILDHOOD. Advances in pediatrics, 1964, Volume: 13 Topics: Adrenocorticotropic Hormone; Antifungal Agents; Child; Dermatology; Dimercaprol; Edetic Acid; Enzyme	1964
[RECENT DATA ON PORPHYRIA]. Acta clinica Belgica, 1964, Volume: 19 Topics: Adenine Nucleotides; Adrenocorticotropic Hormone; Biochemical Phenomena; Biochemistry; Cortisone; Di	1964

Other Studies

15 other studies available for dimercaprol and Porphyria

Article	Year
Porphyria improved after treatment with BAL. Acta medica Scandinavica, 1953, Volume: 145, Issue:5 Topics: Animals; Dimercaprol; Porifera; Porphyrias	1953
BAL therapy of acute porphyrinuria. Neurology, 1954, Volume: 4, Issue:6 Topics: Dimercaprol; Porphyrias; Porphyrins	1954
The effect of BAL on a case of cutaneous porphyria. Acta dermato-venereologica, 1954, Volume: 34, Issue:5 Topics: Administration, Cutaneous; Dimercaprol; Porphyrias; Skin Diseases	1954
Therapy of acute porphyria with BAL and other agents; a report of 19 additional cases. Diseases of the nervous system, 1956, Volume: 17, Issue:6 Topics: Animals; Dimercaprol; Humans; Porifera; Porphyria, Acute Intermittent; Porphyrias	1956
The treatment of acute porphyria with chelating agents: a report of 21 cases. Annals of internal medicine, 1957, Volume: 47, Issue:5 Topics: Chelating Agents; Dimercaprol; Edetic Acid; Humans; Porphyria, Acute Intermittent; Porphyrias	1957
Therapy of acute, chronic and mixed hepatic porphyria patients with chelating agents. Neurology, 1958, Volume: 8, Issue:8 Topics: Chelating Agents; Dimercaprol; Edetic Acid; Humans; Porphyrias; Porphyrias, Hepatic	1958
[Acute porphyria; 2 cases with distinctive neuropsychiatric symptoms treated with BAL]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1958, May-01, Volume: 78, Issue:9 Topics: Dimercaprol; Mental Disorders; Porphyria, Acute Intermittent; Porphyrias	1958
[REANIMATION AND VALUE OF RECENT TREATMENT OF ACUTE PORPHYRIAS]. Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1964, Nov-13, Volume: 115 Topics: Adenine Nucleotides; Barbiturates; Dimercaprol; Drug Therapy; Edetic Acid; Exchange Transfusion, Who	1964
Recovery in a case of ascending Landry paralysis due to porphyria. American practitioner and digest of treatment, 1955, Volume: 6, Issue:6 Topics: Biological Phenomena; Dimercaprol; Guillain-Barre Syndrome; Humans; Paralysis; Porphyrias	1955
Porphyria; its manifestations and treatment with chelating agents. Texas state journal of medicine, 1959, Volume: 55 Topics: Animals; Chelating Agents; Dimercaprol; Edetic Acid; Porifera; Porphyrias	1959
Porphyria cutanea tarda: report of a case effectively treated with dimercaprol (BAL). Archives of internal medicine, 1959, Volume: 104 Topics: Dimercaprol; Humans; Porphyria Cutanea Tarda; Porphyrias	1959
Porphyric psychosis and chelation therapy. Recent advances in biological psychiatry, 1961, Volume: 4 Topics: Animals; Chelation Therapy; Dimercaprol; Edetic Acid; Humans; Mental Disorders; Porifera; Porphyrias	1961
[Acute intermittent porphyria (our personal observations in a family)]. Zeitschrift fur arztliche Fortbildung, 1971, Feb-15, Volume: 65, Issue:4 Topics: Acute Disease; Adrenocorticotropic Hormone; Adult; Biopsy; Chlorpromazine; Cytochromes; Dimercaprol;	1971
[A case of acute intermittent porphyria]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1969, Oct-17, Volume: 24, Issue:46 Topics: Abdomen, Acute; Acute Disease; Adult; Diagnosis, Differential; Dimercaprol; Humans; Male; Porphyrias	1969
[Surgical aspects of acute intermittent porphyria]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1966, Volume: 37, Issue:7 Topics: Abdomen, Acute; Barbiturates; Dimercaprol; Humans; Muscle Cramp; Muscle, Smooth; Porphyrias; Porphyr	1966