dimercaprol has been researched along with Polyarthritis in 10 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral gold (auranofin) has been used in 31 patients, 20 with active rheumatoid arthritis and 11 with active psoriatic arthritis." | 9.05 | Longterm experience with oral gold in rheumatoid arthritis and psoriatic arthritis. ( Dequeker, J; Gevers, G; Vanschoubroek, K; Verdickt, W, 1984) |
| "The authors describe the association of gold salt-induced cholestasis and lymphocytic alveolitis proved by liver biopsy and broncho-alveolar lavage." | 7.67 | Cholestasis and pneumonitis induced by gold therapy. ( Colombel, JF; Delcambre, B; Duquesnoy, B; Farre, JM; Hautefeuille, P; Perez, T; Tonnel, F, 1989) |
| "Oral gold (auranofin) has been used in 31 patients, 20 with active rheumatoid arthritis and 11 with active psoriatic arthritis." | 5.05 | Longterm experience with oral gold in rheumatoid arthritis and psoriatic arthritis. ( Dequeker, J; Gevers, G; Vanschoubroek, K; Verdickt, W, 1984) |
| "The authors describe the association of gold salt-induced cholestasis and lymphocytic alveolitis proved by liver biopsy and broncho-alveolar lavage." | 3.67 | Cholestasis and pneumonitis induced by gold therapy. ( Colombel, JF; Delcambre, B; Duquesnoy, B; Farre, JM; Hautefeuille, P; Perez, T; Tonnel, F, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MCMAHON, JM | 1 |
| WATSON, EM | 1 |
| THOMPSON, M | 1 |
| SINCLAIR, RJ | 1 |
| DUTHIE, JJ | 1 |
| EDSTROM, G | 1 |
| GARDNER, GM | 1 |
| FAIRLEY, DL | 1 |
| KUZELL, WC | 1 |
| Dequeker, J | 1 |
| Verdickt, W | 1 |
| Gevers, G | 1 |
| Vanschoubroek, K | 1 |
| Farre, JM | 1 |
| Perez, T | 1 |
| Hautefeuille, P | 1 |
| Tonnel, F | 1 |
| Colombel, JF | 1 |
| Duquesnoy, B | 1 |
| Delcambre, B | 1 |
| Fraisse, P | 1 |
| Sutter, B | 1 |
| Tritschler, JL | 1 |
| Niederberger, P | 1 |
| Kuntz, JL | 1 |
| Asch, L | 1 |
| Burdeĭnyĭ, AP | 1 |
| Sigidin, IaA | 1 |
| Novoselova, TM | 1 |
| Maslennikov, EIu | 1 |
| Perepechaĭ, LD | 1 |
| Vulkov, GA | 1 |
2 trials available for dimercaprol and Polyarthritis
| Article | Year |
|---|---|
Longterm experience with oral gold in rheumatoid arthritis and psoriatic arthritis.
Topics: Adult; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Clini | 1984 |
[Treatment of psoriatic arthritis with gold salts (chrysotherapy)].
Topics: Adult; Arthritis; Clinical Trials as Topic; Dimercaprol; Drug Therapy, Combination; Female; Gold; Hu | 1986 |
8 other studies available for dimercaprol and Polyarthritis
| Article | Year |
|---|---|
Toxic reaction from gold appearing during ACTH administration; report of a case.
Topics: Adrenocorticotropic Hormone; Arthritis; Arthritis, Rheumatoid; Dimercaprol; Gold; Postoperative Comp | 1952 |
The haematopathological complications of gold therapy: effects of splenectomy and bal.
Topics: Anemia; Anemia, Aplastic; Arthritis; Arthritis, Rheumatoid; Dimercaprol; Gold; Humans; Purpura; Purp | 1953 |
Thrombocytopenic purpura after administration of gold; comparison of treatment with dimercaprol, A.C.T.H., and cortisone.
Topics: Adrenocorticotropic Hormone; Arthritis; Arthritis, Rheumatoid; Cortisone; Dimercaprol; Gold; Purpura | 1954 |
The effects of 2.3-dimercaptopropanol (BAL) on gold reactions.
Topics: Arthritis; Dimercaprol; Gold; Organogold Compounds | 1950 |
Effect of BAL on experimental polyarthritis of rats.
Topics: Animals; Arthritis; Dimercaprol; Rats | 1949 |
Cholestasis and pneumonitis induced by gold therapy.
Topics: Aged; Arthritis; Cholestasis; Dimercaprol; Gold; Humans; Male; Metalloproteins; Organogold Compounds | 1989 |
[Morvan's fibrillary chorea after gold therapy].
Topics: Anti-Inflammatory Agents; Arthritis; Chorea; Dimercaprol; Female; Gold; Humans; Middle Aged; Organog | 1985 |
[Experimental and clinical substantiation of the intra-articular administration of unithiol in reactive traumatic arthritis].
Topics: Animals; Arthritis; Dimercaprol; Female; Injections, Intra-Articular; Knee Injuries; Knee Joint; Mal | 1985 |