dimercaprol has been researched along with Poisoning, Lead in 124 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Congenital lead poisoning is uncommon and there is no consensus on the management of the newborn." | 7.76 | Asymptomatic congenital lead poisoning - case report. ( Chinnakaruppan, NR; Marcus, SM, 2010) |
| "Congenital lead poisoning is uncommon and there is no consensus on the management of the newborn." | 3.76 | Asymptomatic congenital lead poisoning - case report. ( Chinnakaruppan, NR; Marcus, SM, 2010) |
| "The delayed treatment of lead poisoning may lead to irreversible motor neuron defect." | 3.74 | Quadriplegia due to lead-contaminated opium--case report. ( Aghdashi, M; Beigmohammadi, MT; Karvandian, K; Mojtahedzadeh, M; Najafi, A, 2008) |
| " The mother was prescribed a single course of oral succimer late in the third trimester of pregnancy, without any appreciable change in her blood lead." | 3.71 | Lead poisoning and chelation in a mother-neonate pair. ( Horowitz, BZ; Mirkin, DB, 2001) |
| "Although treatment has been well defined for childhood lead poisoning and for industrial lead exposure, the treatment of lead nephropathy has been poorly studied." | 3.65 | Chelation therapy in lead nephropathy. ( Morgan, JM, 1975) |
| " A dose-response study showed that the highest dose of DMPS (200 mumol/kg, ip) removed Pb from kidneys, liver, and bone, while the lower doses (25 and 50 mumol/kg) chelated Pb only from the kidneys." | 1.27 | Chelation of lead by dimercaptopropane sulfonate and a possible diagnostic use. ( Cherian, MG; Twarog, T, 1984) |
| "The clinical signs were jaundice and amaurosis." | 1.27 | Icterus and amaurosis caused by lead poisoning in a cynomolgus monkey (Macaca fascicularis). ( Dorrestein, GM; Lumeij, JT, 1986) |
| "These data suggest that neurological manifestations occur frequently in those abusing leaded gasoline and that chelation therapy has an important place in their management." | 1.26 | The neurological manifestations of chronic inhalation of leaded gasoline. ( Boeckx, RL; Chow, PN; Rjani, KR; Seshia, SS, 1978) |
| "Forty-seven children treated for lead poisoning (PbB 50 to 365 microgram/dl) were compared to siblings next in age (PbB less than 40 microgram/dl) by a battery of psychologic tests." | 1.26 | IQ following treatment of lead poisoning: a patient-sibling comparison. ( Growe, G; Krall, V; Lazar, BS; McCaughran, DA; Novar, L; O'Connell, L; Rayson, B; Rozenfeld, IH; Sachs, HK; Yongsmith, N, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 98 (79.03) | 18.7374 |
| 1990's | 14 (11.29) | 18.2507 |
| 2000's | 7 (5.65) | 29.6817 |
| 2010's | 4 (3.23) | 24.3611 |
| 2020's | 1 (0.81) | 2.80 |
| Authors | Studies |
|---|---|
| Hsiao, CY | 1 |
| Gresham, C | 1 |
| Marshall, MR | 1 |
| Stierman, B | 1 |
| Hauptman, M | 1 |
| Woolf, AD | 1 |
| Permar, S | 1 |
| Gorman, K | 1 |
| Lercher, D | 1 |
| Bradford, KK | 1 |
| Grasso, IA | 1 |
| Blattner, MR | 1 |
| Short, T | 1 |
| Downs, JW | 1 |
| Spitz, M | 1 |
| Lucato, LT | 1 |
| Haddad, MS | 1 |
| Barbosa, ER | 1 |
| LUSKY, LM | 1 |
| BRAUN, HA | 1 |
| LAUG, EP | 1 |
| WEATHERALL, M | 1 |
| GERMUTH, FG | 2 |
| EAGLE, H | 2 |
| CHIODI, H | 1 |
| SAMMARTINO, RA | 1 |
| Beigmohammadi, MT | 1 |
| Aghdashi, M | 1 |
| Najafi, A | 1 |
| Mojtahedzadeh, M | 1 |
| Karvandian, K | 1 |
| RYDER, HW | 1 |
| KEHOE, RA | 2 |
| Chinnakaruppan, NR | 1 |
| Marcus, SM | 1 |
| GIANNATTASIO, RC | 2 |
| PIROZZI, MJ | 2 |
| BEDO, AV | 1 |
| JENNINGS, KG | 1 |
| MOESCHLIN, S | 1 |
| SCHECHTERMAN, L | 1 |
| DEANE, GE | 1 |
| HELDRICH, FJ | 1 |
| BRADLEY, JE | 3 |
| SARTORELLI, E | 1 |
| MARCONI, E | 1 |
| BALDWIN, RW | 1 |
| MENON, G | 1 |
| BAUMGARTNER, RJ | 1 |
| GENTILE, G | 1 |
| BUSHEV, TA | 1 |
| HORIUCHI, K | 1 |
| SMITH, HD | 1 |
| JACOBZINER, H | 1 |
| RAYBIN, HW | 1 |
| ASTOLFI, E | 1 |
| ABDEL-GHAFFAR, Y | 1 |
| SHERIF, YA | 1 |
| EL-MASSRY, ZH | 1 |
| BARSOOM, KA | 1 |
| ARONSON, AL | 1 |
| HAMMOND, PB | 1 |
| CALVO MELENDRO, J | 1 |
| GRAZIANI, G | 1 |
| VIGLIANI, EC | 1 |
| ZURLO, N | 1 |
| Mycyk, MB | 1 |
| Leikin, JB | 1 |
| Domingo-Claros, A | 1 |
| Alonso, E | 1 |
| Banda Ed, Ede L | 1 |
| ANDERSON, AB | 1 |
| ENNIS, JM | 1 |
| HARRISON, HE | 1 |
| BASTRUP-MADSEN, P | 1 |
| Florin, TA | 1 |
| Brent, RL | 1 |
| Weitzman, M | 1 |
| Shaltout, A | 1 |
| Yaish, SA | 1 |
| Fernando, N | 1 |
| Aposhian, HV | 1 |
| Trimmer, LM | 1 |
| Sensirivatana, R | 1 |
| Supachadhiwong, O | 1 |
| Phancharoen, S | 1 |
| Mitrakul, C | 1 |
| de Francisci, G | 1 |
| Magalini, SI | 1 |
| Piomelli, S | 1 |
| Rosen, JF | 1 |
| Chisolm, JJ | 10 |
| Graef, JW | 2 |
| Twarog, T | 1 |
| Cherian, MG | 2 |
| Green, VA | 2 |
| Roberts, D | 1 |
| Wasserman, GS | 1 |
| Haust, HL | 1 |
| Ali, H | 1 |
| Haines, DS | 1 |
| Forret, CJ | 1 |
| Bratton, GR | 1 |
| Zmudzki, J | 1 |
| Kincaid, N | 1 |
| Joyce, J | 1 |
| Linden, MA | 1 |
| Manton, WI | 1 |
| Stewart, RM | 1 |
| Thal, ER | 1 |
| Feit, H | 1 |
| Kurt, TL | 1 |
| McAnalley, BH | 1 |
| Garriott, JC | 1 |
| Twarog, TA | 1 |
| Burns, CB | 1 |
| Currie, B | 1 |
| Royce, S | 1 |
| Rosenberg, J | 1 |
| Mortensen, ME | 1 |
| Walson, PD | 1 |
| Bhattacharya, A | 1 |
| Smelser, DT | 1 |
| Berger, O | 1 |
| Shukla, R | 1 |
| Medvedovic, M | 1 |
| Krishnaswamy, K | 1 |
| Kumar, BD | 1 |
| Gordon, RA | 1 |
| Roberts, G | 1 |
| Amin, Z | 1 |
| Williams, RH | 1 |
| Paloucek, FP | 1 |
| Horowitz, BZ | 1 |
| Mirkin, DB | 1 |
| Kon, T | 1 |
| Akiyama, K | 1 |
| Aiba, T | 1 |
| Seshia, SS | 1 |
| Rjani, KR | 1 |
| Boeckx, RL | 1 |
| Chow, PN | 1 |
| Sachs, HK | 2 |
| Krall, V | 1 |
| McCaughran, DA | 1 |
| Rozenfeld, IH | 1 |
| Yongsmith, N | 1 |
| Growe, G | 1 |
| Lazar, BS | 1 |
| Novar, L | 1 |
| O'Connell, L | 1 |
| Rayson, B | 1 |
| Gordon, NC | 1 |
| Brown, S | 1 |
| Khosla, VM | 1 |
| Hansen, LS | 1 |
| Pincus, D | 1 |
| Saccar, CV | 1 |
| Barltrop, D | 2 |
| Morgan, JM | 1 |
| Hornbostel, H | 1 |
| Kaufmann, W | 1 |
| Siegenthaler, W | 1 |
| Graziano, JH | 2 |
| Leong, JK | 1 |
| Friedheim, E | 1 |
| Janakiraman, N | 1 |
| Seeler, RA | 2 |
| Royal, JE | 1 |
| Chen, MF | 1 |
| Santhanakrishnan, BR | 1 |
| Bai, TP | 1 |
| Sitarz, AL | 1 |
| Cohen, DJ | 1 |
| Johnson, WT | 1 |
| Caparulo, BK | 1 |
| Molina-Ballesteros, G | 1 |
| Hofmann, U | 1 |
| Segewitz, G | 1 |
| Lolacono, NJ | 1 |
| Moulton, T | 1 |
| Mitchell, ME | 1 |
| Slavkovich, V | 1 |
| Zarate, C | 1 |
| Kosnett, MJ | 1 |
| Roberge, RJ | 1 |
| Martin, TG | 1 |
| Suarez, CR | 1 |
| Black, LE | 1 |
| Hurley, RM | 1 |
| O'Connor, ME | 1 |
| Yver, A | 1 |
| Leverger, G | 1 |
| Iniguez, JL | 1 |
| Gouraud, F | 1 |
| Lamour, C | 1 |
| Garnier, R | 1 |
| Turbier, C | 1 |
| Delour, M | 1 |
| Lasfargues, G | 1 |
| Tallis, GA | 1 |
| Cohen, N | 1 |
| Modai, D | 1 |
| Golik, A | 1 |
| Pik, A | 1 |
| Weissgarten, J | 1 |
| Sigler, E | 1 |
| Averbukh, Z | 1 |
| Nelson, MS | 1 |
| Abu Melha, A | 1 |
| Ahmed, NA | 1 |
| el Hassan, AY | 1 |
| Vincent, D | 1 |
| Lagarde, C | 1 |
| Peyronnet, P | 1 |
| Benevent, D | 1 |
| Aldigier, JC | 1 |
| Leroux-Robert, C | 1 |
| Nyhan, WL | 1 |
| Sawyer, M | 1 |
| Kearney, T | 1 |
| Spector, S | 2 |
| Hilton, S | 1 |
| Lumeij, JT | 1 |
| Dorrestein, GM | 1 |
| Flora, SS | 1 |
| Tandon, SK | 2 |
| Flora, SJ | 1 |
| Singh, S | 1 |
| Thomas, DJ | 1 |
| Wise, GW | 1 |
| Smull, NW | 1 |
| Fejerman, N | 1 |
| Gimenez, ER | 1 |
| Vallejo, NE | 1 |
| Medina, CS | 1 |
| Shellshear, ID | 1 |
| Schubert, J | 1 |
| Sheehan, TJ | 1 |
| Gravel, SR | 1 |
| Gras, G | 2 |
| Giono, H | 2 |
| Anku, VD | 1 |
| Harris, JW | 1 |
| Haenggeli, CA | 1 |
| Katakalidis, G | 1 |
| Stoll, E | 1 |
| Aaseth, J | 1 |
| Vitale, LF | 1 |
| Fine, BP | 1 |
| Barth, A | 1 |
| Filkin, K | 1 |
| Sundaravalli, N | 1 |
| Sundaram, VM | 1 |
| Raju, VB | 1 |
| Orson, J | 1 |
| May, JB | 1 |
| Coffin, R | 1 |
| Phillips, JL | 1 |
| Staples, WI | 1 |
| St George, IM | 1 |
| Blanksma, LA | 1 |
| Murray, EF | 1 |
| O'Connell, MJ | 1 |
| Clarkson, TW | 1 |
| Willemsens, LC | 1 |
| van der Kerk, GJ | 1 |
| van der Want, GM | 1 |
| Dolan, TF | 1 |
| Wang, SF | 1 |
| Meyers, A | 1 |
| Bartsocas, CS | 1 |
| Grunt, JA | 1 |
| Boylen, GW | 1 |
| Brandt, IK | 1 |
| Kopito, L | 1 |
| Shwachman, H | 1 |
| Alessio, L | 1 |
| Farina, G | 1 |
| Lange, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Transdermal Absorption of DMPS and Its Effect on Urinary Mercury Excretion[NCT01059474] | Phase 1 | 9 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
15 reviews available for dimercaprol and Poisoning, Lead
| Article | Year |
|---|---|
Treatment of lead and arsenic poisoning in anuric patients - a case report and narrative review of the literature.
Topics: Adult; Animals; Anuria; Arsenic Poisoning; Chelating Agents; Continuous Renal Replacement Therapy; D | 2019 |
DMSA and DMPS--water soluble antidotes for heavy metal poisoning.
Topics: Animals; Antidotes; Arsenic Poisoning; Biotransformation; Cadmium Poisoning; Dimercaprol; Forecastin | 1983 |
[Lead poisoning].
Topics: Adrenal Cortex Hormones; Calcium Gluconate; Dimercaprol; Edetic Acid; Gastrointestinal Diseases; Hem | 1983 |
Poisoning from heavy metals (mercury, lead, and cadmium).
Topics: Animals; Body Burden; Cadmium Poisoning; Chelating Agents; Child, Preschool; Dimercaprol; Disease Ou | 1980 |
Chelation therapy for childhood lead poisoning. The changing scene in the 1990s.
Topics: Chelation Therapy; Child; Dimercaprol; Edetic Acid; Humans; Lead; Lead Poisoning; Penicillamine; Suc | 1993 |
Lead toxicity.
Topics: Adult; Chelating Agents; Child; Child, Preschool; Dimercaprol; Edetic Acid; Female; Humans; Incidenc | 1998 |
Aggressive approach in the treatment of acute lead encephalopathy with an extraordinarily high concentration of lead.
Topics: Brain Diseases; Child, Preschool; Dimercaprol; Edetic Acid; Environmental Exposure; Female; Humans; | 1998 |
Recognition and management of children with increased lead absorption.
Topics: Absorption; Acute Disease; Behavior; Bone and Bones; Bone Marrow; Brain Diseases; Child; Dimercaprol | 1979 |
Unanswered questions in metal chelation.
Topics: Animals; Arsenic Poisoning; Chelating Agents; Chelation Therapy; Dimercaprol; Edetic Acid; Humans; L | 1992 |
Whole bowel irrigation in an acute oral lead intoxication.
Topics: Administration, Oral; Aged; Aged, 80 and over; Alzheimer Disease; Chelation Therapy; Dimercaprol; Hu | 1992 |
The use of chelating agents in the treatment of acute and chronic lead intoxication in childhood.
Topics: Acute Disease; Amino Acids; Animals; Brain Diseases; Child; Child, Preschool; Chronic Disease; Creat | 1968 |
Lead poisoning.
Topics: Air Pollution; Bone and Bones; Child, Preschool; Chronic Disease; Dexamethasone; Dimercaprol; Edetic | 1971 |
Epidemiological and experimental aspects of lead and mercury contamination of food.
Topics: Animals; Antidotes; Dimercaprol; Edetic Acid; Erythrocytes; Feces; Food Contamination; Humans; Intes | 1971 |
Treatment of lead poisoning.
Topics: Adult; Age Factors; Child; Child, Preschool; Dimercaprol; Diuresis; Edetic Acid; Humans; Infant; Inf | 1971 |
[Prevention and treatment of lead poisoning with chelating agents: critical review].
Topics: Dimercaprol; Edetic Acid; Humans; Injections, Intramuscular; Injections, Intravenous; Lead Poisoning | 1971 |
1 trial available for dimercaprol and Poisoning, Lead
| Article | Year |
|---|---|
Controlled study of meso-2,3-dimercaptosuccinic acid for the management of childhood lead intoxication.
Topics: Administration, Oral; Ambulatory Care; Aminolevulinic Acid; Calcium; Chelating Agents; Child; Child, | 1992 |
108 other studies available for dimercaprol and Poisoning, Lead
| Article | Year |
|---|---|
Severe lead poisoning requiring hospitalization: A case report.
Topics: Chelating Agents; Child, Preschool; Dimercaprol; Female; Hospitalization; Humans; Lead Poisoning; Ma | 2020 |
Rare etiology of abdominal pain in an adolescent female.
Topics: Abdominal Pain; Adolescent; Chelating Agents; Diagnosis, Differential; Dimercaprol; Edetic Acid; Fem | 2015 |
Severe Systemic Lead Toxicity Resulting From Extra-Articular Retained Shrapnel Presenting as Jaundice and Hepatitis: A Case Report and Review of the Literature.
Topics: Abdominal Pain; Adult; Chelating Agents; Chelation Therapy; Constipation; Dimercaprol; Foreign Bodie | 2017 |
Choreoathetosis secondary to lead toxicity.
Topics: Adult; Athetosis; Chelating Agents; Chorea; Dimercaprol; Edetic Acid; Humans; Lead; Lead Poisoning; | 2008 |
The protective action of BAL on experimental poisoning by lead, tungsten, copper and Paris green.
Topics: Arsenites; Copper; Dimercaprol; Lead Poisoning; Tungsten | 1948 |
Effects of BAL and BAL glucoside in acute lead acetate poisoning.
Topics: Acetates; Dimercaprol; Glucosides; Lead; Lead Poisoning; Organometallic Compounds | 1948 |
The efficacy of BAL (2,3-dimercaptopropanol) in the treatment of experimental lead poisoning in rabbits.
Topics: Animals; Dimercaprol; Lead; Lead Poisoning; Rabbits | 1948 |
Nephrotoxic and renotropic effects of lead on white rats and its prevention by B.A.L.
Topics: Animals; Dimercaprol; Kidney Diseases; Lead; Lead Poisoning; Rats | 1947 |
The efficacy of BAL in the treatment of experimental lead poisoning in rabbits.
Topics: Animals; Dimercaprol; Lagomorpha; Lead Poisoning; Rabbits | 1948 |
Quadriplegia due to lead-contaminated opium--case report.
Topics: Adult; Chelating Agents; Diagnosis, Differential; Dimercaprol; Drug Contamination; Edetic Acid; Huma | 2008 |
The effect of dithiopropanol (BAL) on human lead intoxication.
Topics: Dimercaprol; Humans; Lead Poisoning | 1947 |
Asymptomatic congenital lead poisoning - case report.
Topics: Adult; Dimercaprol; Exchange Transfusion, Whole Blood; Female; Humans; Infant, Newborn; Lead; Lead P | 2010 |
BAL therapy in chronic lead poisoning.
Topics: Chronic Disease; Dimercaprol; Humans; Lead; Lead Poisoning | 1952 |
[Comparison of the therapeutic effect of BAL or sodium citrate in experimental lead poisoning].
Topics: Citrates; Dimercaprol; Lead; Lead Poisoning; Sodium Citrate | 1952 |
The use of bal in the treatment of acute lead encephalopathy.
Topics: Dimercaprol; Humans; Lead Poisoning | 1953 |
BAL therapy in acute lead encephalopathy.
Topics: Brain; Brain Diseases; Dimercaprol; Humans; Lead Poisoning; Neurotoxicity Syndromes | 1953 |
[Case of chiropodal tetraplegia due to subacute lead and arsenic poisoning treated with BAL..].
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Humans; Lead Poisoning; Paralysis; Poisoning; Quadriplegia | 1954 |
[Subacute lead poisoning due to accidental penetration of lead treated with mercaprol; etiopathogenic and medico-legal aspects].
Topics: Dimercaprol; Humans; Lead Poisoning | 1954 |
The comparison of BAL (2, 3-dimercaptopropanol) and Ca EDTA (calcium ethylene diamine tetra acetate) in the treatment of lead encephalopathy.
Topics: Calcium, Dietary; Dimercaprol; Edetic Acid; Ethylenes; Humans; Lead Poisoning; Mental Disorders; Psy | 1957 |
Subsequent mental development of children with lead encephalopathy, as related to type of treatment.
Topics: Brain; Brain Diseases; Child; Dimercaprol; Edetic Acid; Humans; Infant; Lead Poisoning | 1958 |
[Experimental research on lead poisoning. IV. Lead nitrate poisoning & BAL].
Topics: Child; Dimercaprol; Humans; Infant; Lead; Lead Poisoning; Nitrates; Nitrogen Oxides | 1959 |
[On the problem of the use unithiol in lead poisoning].
Topics: Dimercaprol; Humans; Lead Poisoning; Unithiol | 1961 |
[Lead poisoning].
Topics: Dimercaprol; Humans; Lead Poisoning; Occupational Diseases | 1963 |
PEDIATRIC LEAD POISONING.
Topics: Anemia; Anemia, Hypochromic; Blood Chemical Analysis; Body Fluids; Child; Dimercaprol; Edetic Acid; | 1964 |
LEAD POISONING TREATED WITH BAL.
Topics: Dimercaprol; Edetic Acid; Humans; Infant; Lead Poisoning; Toxicology | 1964 |
[THERAPEUTICS AND PROPHYLAXIS OF INTOXICATIONS IN INFANCY].
Topics: Accident Prevention; Arsenic; Child; Dimercaprol; Edetic Acid; Emergency Service, Hospital; Health E | 1964 |
LEAD ENCEPHALOPATHY: CASE REPORT.
Topics: Blood Chemical Analysis; Coma; Delirium; Dimercaprol; Lead Poisoning; Neurologic Examination; Neurot | 1963 |
EFFECT OF TWO CHELATING AGENTS ON THE DISTRIBUTION AND EXCRETION OF LEAD.
Topics: Biological Transport; Body Fluids; Chelating Agents; Dimercaprol; Edetic Acid; Feces; Lead Poisoning | 1964 |
Value of calcium disodium ethylenediaminetetraacetate and British anti-lewisite in therapy of lead poisoning.
Topics: Calcium; Dimercaprol; Edetic Acid; Lead Poisoning | 1961 |
[Accidental lead poisoning].
Topics: Bone and Bones; Dimercaprol; Lead; Lead Poisoning | 1950 |
[Effect of BAL on hematic crasis and on the bone marrow picture in experimental lead poisoning].
Topics: Blood; Bone Marrow; Dimercaprol; Lead; Lead Poisoning | 1951 |
The effects of BAL on the metabolism of lead and on the symptomatology in lead intoxication.
Topics: Dimercaprol; Humans; Lead; Lead Poisoning | 1951 |
Combined exchange transfusion and chelation therapy for neonatal lead poisoning.
Topics: Adult; Ceramics; Chelating Agents; Chelation Therapy; Combined Modality Therapy; Dimercaprol; Edetic | 2004 |
Schizophrenia and refractory anaemia with ring sideroblasts.
Topics: Adult; Anemia, Sideroblastic; Blood Transfusion; Chelating Agents; Dimercaprol; Edetic Acid; Female; | 2004 |
The effect of dimercaprol on lead poisoning in mice.
Topics: Animals; Dimercaprol; Lead; Lead Poisoning; Mice | 1949 |
Treatment of lead encephalopathy with PAL (2.3-dimercaptopropanol).
Topics: Brain; Dimercaprol; Humans; Lead; Lead Poisoning; Neurotoxicity Syndromes | 1950 |
Dimercaprol in acute lead poisoning.
Topics: Dimercaprol; Humans; Lead; Lead Poisoning | 1950 |
The need for vigilance: the persistence of lead poisoning in children.
Topics: Cheek; Chelation Therapy; Child, Preschool; Dimercaprol; Drug Therapy, Combination; Edema; Edetic Ac | 2005 |
Lead encephalopathy in infants in Kuwait. A study of 20 infants with particular reference to clinical presentation and source of lead poisoning.
Topics: Brain Diseases; Dimercaprol; Edetic Acid; Female; Humans; Infant; Lead; Lead Poisoning; Male; Sulfid | 1981 |
Lead poisoning--a continuing adversary.
Topics: Brain Edema; Child; Child, Preschool; Dimercaprol; Edetic Acid; Environmental Pollutants; Humans; Le | 1983 |
Neonatal lead poisoning. An unusual clinical manifestation.
Topics: Adult; Bone and Bones; Diagnosis, Differential; Dimercaprol; Drug Therapy, Combination; Edetic Acid; | 1983 |
Management of childhood lead poisoning.
Topics: Brain Diseases; Chelating Agents; Child; Dimercaprol; Environmental Exposure; Glucosephosphate Dehyd | 1984 |
Chelation of lead by dimercaptopropane sulfonate and a possible diagnostic use.
Topics: Administration, Oral; Animals; Chelating Agents; Dimercaprol; Injections, Intraperitoneal; Kidney; L | 1984 |
Multiple chelations for chronic plumbism (a case report).
Topics: Child, Preschool; Dimercaprol; Edetic Acid; Humans; Lead Poisoning; Male | 1980 |
Short-term administration of dimercaptopropanol (BAL) and calcium disodium edetate (EDTA) for diagnostic and therapeutic lead mobilization.
Topics: Calcium; Child, Preschool; Dimercaprol; Edetic Acid; Female; Follow-Up Studies; Humans; Lead; Lead P | 1980 |
Thiamin as treatment of lead poisoning in ruminants.
Topics: Animals; Cattle; Cattle Diseases; Deer; Dimercaprol; Edetic Acid; Female; Goats; Lead Poisoning; Thi | 1981 |
Lead poisoning from retained bullets. Pathogenesis, diagnosis, and management.
Topics: Adult; Cysts; Dimercaprol; Edetic Acid; Female; Humans; Intervertebral Disc; Lead Poisoning; Male; M | 1982 |
Lead encephalopathy from gasoline sniffing: successful treatment with chelation.
Topics: Adolescent; Brain Diseases; Chelating Agents; Dexamethasone; Dimercaprol; Edetic Acid; Gasoline; Hum | 1982 |
Chelation of lead with DMPS and BAL in rats injected with lead.
Topics: Aminolevulinic Acid; Animals; Chelating Agents; Dimercaprol; Lead; Lead Poisoning; Male; Rats; Rats, | 1983 |
The efficacy of chelation therapy and factors influencing mortality in lead intoxicated petrol sniffers.
Topics: Chelating Agents; Chelation Therapy; Dimercaprol; Edetic Acid; Gasoline; Humans; Lead; Lead Poisonin | 1995 |
Treatment guidelines for lead exposure in children. American Academy of Pediatrics Committee on Drugs.
Topics: Chelating Agents; Child; Dimercaprol; Edetic Acid; Humans; Lead Poisoning; Penicillamine; Succimer | 1995 |
Chelation therapy in workers with lead exposure.
Topics: Chelation Therapy; Dimercaprol; Edetic Acid; Humans; Lead; Lead Poisoning; Occupational Exposure; Oc | 1993 |
The effect of succimer therapy in lead intoxication using postural balance as a measure: a case study in a nine year old child.
Topics: Administration, Oral; Child; Dimercaprol; Drug Administration Schedule; Edetic Acid; Humans; Lead Po | 1998 |
Lead poisoning and chelation in a mother-neonate pair.
Topics: Adult; Chelating Agents; Chelation Therapy; Dimercaprol; Edetic Acid; Female; Fetal Blood; Humans; I | 2001 |
[Shotgun injury of head and neck: case report].
Topics: Chelating Agents; Dimercaprol; Edetic Acid; Head Injuries, Penetrating; Humans; Lead Poisoning; Male | 2002 |
The neurological manifestations of chronic inhalation of leaded gasoline.
Topics: Adolescent; Adult; Child; Child, Preschool; Dimercaprol; Edetic Acid; Electrocardiography; Electroen | 1978 |
IQ following treatment of lead poisoning: a patient-sibling comparison.
Topics: Child; Child, Preschool; Dimercaprol; Edetic Acid; Family; Female; Humans; Infant; Intelligence; Int | 1978 |
Lead poisoning. A comprehensive review and report of a case.
Topics: Adult; Anemia; Child; Diagnosis, Differential; Dimercaprol; Edetic Acid; Gingival Hyperplasia; Hair; | 1979 |
Lead poisoning.
Topics: Child; Dimercaprol; Edetic Acid; Humans; Lead; Lead Poisoning; Penicillamine | 1979 |
Chelation therapy in lead nephropathy.
Topics: Acute Kidney Injury; Administration, Oral; Chelating Agents; Creatinine; Dimercaprol; Drug Eruptions | 1975 |
[Therapy of poisoning with heavy metals].
Topics: Aminolevulinic Acid; Cadmium Poisoning; Chromium; Deferoxamine; Dimercaprol; Edetic Acid; Ferrocyani | 1975 |
2,3-Dimercaptosuccinic acid: a new agent for the treatment of lead poisoning.
Topics: Animals; Dimercaprol; Lead; Lead Poisoning; Male; Mice; Rats; Succimer; Sulfhydryl Compounds | 1978 |
Hemolysis during BAL chelation therapy for high blood lead levels in two G6PD deficient children.
Topics: Child, Preschool; Dimercaprol; Edetic Acid; Glucosephosphate Dehydrogenase Deficiency; Hemolysis; Hu | 1978 |
Lead poisoning in children in Madras city.
Topics: Child, Preschool; Dimercaprol; Female; Humans; India; Infant; Lead Poisoning; Male; Urban Population | 1978 |
Letter: Severe lead poisoning in a 6-month-old infant.
Topics: Anemia; Bone Development; Ceramics; Citrus; Diagnosis, Differential; Dimercaprol; Edetic Acid; Femal | 1975 |
Pica and elevated blood lead level in autistic and atypical children.
Topics: Adolescent; Autistic Disorder; Cerebrospinal Fluid Proteins; Child; Child, Preschool; Dimercaprol; E | 1976 |
[Lead air pollution in industrial areas. VII. Therapy].
Topics: Dimercaprol; Drug Evaluation; Humans; Lead Poisoning; Penicillamine | 1977 |
Influence of chelation therapy on acute lead intoxication in rats.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Body Weight; Bone and Bones; Chelating Agents; Dimercap | 1975 |
BAL, EDTA, DMSA and DMPS in the treatment of lead poisoning in children.
Topics: Administration, Oral; Beverages; Chelation Therapy; Child; Child, Preschool; Dimercaprol; Edetic Aci | 1992 |
Elevated lead levels in a patient with sickle cell disease and inappropriate secretion of antidiuretic hormone.
Topics: Anemia, Sickle Cell; Chelation Therapy; Child, Preschool; Dimercaprol; Edetic Acid; Female; Humans; | 1992 |
CaEDTA vs CaEDTA plus BAL to treat children with elevated blood lead levels.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Chelating Agents; Child, Preschool; Dimercaprol; | 1992 |
[Lead poisoning in children. Apropos of 129 cases].
Topics: Chelating Agents; Child; Dimercaprol; Edetic Acid; Female; Humans; Lead Poisoning; Male | 1991 |
Acute lead arsenate poisoning.
Topics: Adult; Aged; Aged, 80 and over; Arsenates; Arsenic Poisoning; Chelation Therapy; Dimercaprol; Edetic | 1989 |
An esoteric occupational hazard for lead poisoning.
Topics: Adult; Aged; Dimercaprol; Edetic Acid; Epidemiologic Methods; Humans; Ink; Israel; Lead Poisoning; M | 1986 |
Lead toxicity masquerading as sickle cell crisis.
Topics: Anemia, Sickle Cell; Child; Diagnostic Errors; Dimercaprol; Edetic Acid; Humans; Lead Poisoning; Mal | 1986 |
Traditional remedies and lead intoxication.
Topics: Bone and Bones; Child, Preschool; Diarrhea; Dimercaprol; Edetic Acid; Female; Humans; Infant; Lead; | 1987 |
Treatment of lead poisoning with unithiol in chronic renal failure.
Topics: Aged; Dimercaprol; Female; Humans; Kidney Failure, Chronic; Lead Poisoning; Unithiol | 1986 |
Lead intoxication in children.
Topics: Child; Child, Preschool; Dimercaprol; Edetic Acid; Female; Heme; Humans; Infant; Lead; Lead Poisonin | 1985 |
Icterus and amaurosis caused by lead poisoning in a cynomolgus monkey (Macaca fascicularis).
Topics: Animals; Blindness; Dimercaprol; Jaundice; Lead Poisoning; Macaca mulatta; Male; Monkey Diseases | 1986 |
Chelation in metal intoxication. XV: Influence of dimercaptopropane sulphonate (DMPS) on lead poisoned rats with normal or damaged kidneys.
Topics: Animals; Chelating Agents; Dimercaprol; Kidney Diseases; Lead Poisoning; Male; Organometallic Compou | 1985 |
Bal therapy in human lead poisoning.
Topics: Adult; Dimercaprol; Humans; Lead Poisoning; Middle Aged | 1985 |
Use of 2,3-dimercaptopropane-1-sulfonate in treatment of lead poisoning in children.
Topics: Aspartate Aminotransferases; Child, Preschool; Copper; Dimercaprol; Female; Humans; Lead; Lead Poiso | 1985 |
Lead survey of selected children in Kansas City and some unusual cases.
Topics: Anemia, Hypochromic; Child, Preschool; Dimercaprol; Edetic Acid; Female; Health Surveys; Humans; Inf | 1973 |
Lennox's syndrome and lead intoxication.
Topics: Anticonvulsants; Child; Child, Preschool; Clinical Enzyme Tests; Dimercaprol; Edetic Acid; Electroen | 1973 |
Lead poisoning in childhood: a case report with environmental implications.
Topics: Adult; Child; Child, Preschool; Dimercaprol; Dust; Edetic Acid; Environmental Exposure; Female; Huma | 1973 |
Heavy metals--toxicity and environmental pollution.
Topics: Air Pollution; Animals; Antibody Formation; Beryllium; Cadmium; Cats; Chelating Agents; Chromosomes; | 1973 |
Childhood lead poisoning: medical review.
Topics: Child, Preschool; Dimercaprol; Edetic Acid; Heme; Humans; Infant; Lead Poisoning | 1974 |
Eight children with coexistent sickle cell anemia and plumbism.
Topics: Anemia, Sickle Cell; Blood Transfusion; Chelating Agents; Dimercaprol; Edetic Acid; Female; Glucosep | 1974 |
[Action of dimercaprol (BAL) on the experimental poisoning of the cynocephale monkey (Papio papio) with dibutyl lead diacetate (DPD). Comparison with toxicity to rats].
Topics: Animals; Cestode Infections; Dimercaprol; Haplorhini; Lead Poisoning; Rats | 1971 |
Peripheral neuropathy and lead poisoning in a child with sickle-cell anemia. Case report and review of the literature.
Topics: Anemia, Sickle Cell; Blood Urea Nitrogen; Calcium; Child; Diagnosis, Differential; Dimercaprol; Edet | 1974 |
[Lead encephalopathy in two infants].
Topics: Brain Diseases; Dimercaprol; Edetic Acid; Female; Humans; Infant; Knee; Lead Poisoning; Male; Penici | 1972 |
Heavy metal poisoning: mercury and lead.
Topics: Adolescent; Adult; Child; Child, Preschool; Diagnosis, Differential; Dimercaprol; Edetic Acid; Envir | 1972 |
[Recent advance in the therapy of metal poisoning with complexing agents].
Topics: Arsenic Poisoning; Carbon Isotopes; Chelating Agents; Deferoxamine; Dimercaprol; Edetic Acid; Humans | 1972 |
Urinary excretion of delta aminolevulinic acid after discontinuance of therapy for lead poisoning. A test for adequacy of therapy.
Topics: Child; Child, Preschool; Dimercaprol; Edetic Acid; Humans; Lead; Lead Poisoning; Levulinic Acids; Re | 1972 |
Treatment of lead poisoning.
Topics: Administration, Oral; Adult; Anemia, Aplastic; Chelating Agents; Child; Dimercaprol; Edetic Acid; En | 1972 |
Lead encephalopathy: report of a case.
Topics: Brain Diseases; Dimercaprol; Humans; Infant; Lead Poisoning; Male | 1972 |
Lead intoxication in children: a current problem in Providence, Rhode Island.
Topics: Child, Preschool; Dimercaprol; Edetic Acid; Female; Humans; Infant; Lead Poisoning; Rhode Island | 1965 |
Treatment of lead encephalopathy in children.
Topics: Brain Diseases; Calcium; Child, Preschool; Dimercaprol; Edetic Acid; Female; Humans; Infant; Lead Po | 1966 |
Prevention, diagnosis, and treatment of lead poisoning in childhood.
Topics: Adrenal Cortex Hormones; Child; Child, Preschool; Dimercaprol; Edetic Acid; Environment; Humans; Lea | 1969 |
Two men with lead poisoning.
Topics: Adult; Chelating Agents; Dimercaprol; Drug Hypersensitivity; Edetic Acid; Humans; Lead; Lead Poisoni | 1970 |
Ambulatory treatment of lead poisoning: report of 1,155 cases.
Topics: Ambulatory Care; Angioedema; Blood Chemical Analysis; Child; Child, Preschool; Diarrhea; Dimercaprol | 1970 |
Poisoning due to heavy metals.
Topics: Arsenic Poisoning; Cadmium Poisoning; Chelating Agents; Child; Child, Preschool; Copper; Deferoxamin | 1970 |
[Action of several thiols on experimental poisoning by dibutyl lead diacetate in rats].
Topics: Animals; Dimercaprol; Female; Glutathione; Injections, Intraperitoneal; Lead Poisoning; Penicillamin | 1971 |
Treatment of lead poisoning at Yale-New Haven Hospital 1970.
Topics: Chelating Agents; Dimercaprol; Edetic Acid; Injections, Intramuscular; Lead Poisoning | 1971 |
Treatment of acute lead intoxication--choice of chelating agents and supportive therapeutic measures.
Topics: Acute Kidney Injury; Chelating Agents; Dimercaprol; Edetic Acid; Environmental Exposure; Humans; Lea | 1970 |
Oral D-penicillamine and intramuscular BAL+EDTA in the treatment of lead accumulation.
Topics: Administration, Oral; Chelating Agents; Child; Child, Preschool; Diet; Dimercaprol; Edetic Acid; Ele | 1971 |
Lead intoxication in children. Diagnosis and treatment.
Topics: Age Factors; Chelating Agents; Child, Preschool; Dimercaprol; Edetic Acid; Female; Humans; Infant; L | 1971 |
[Chemica damage to the eye in industrial medicine].
Topics: Argyria; Burns, Chemical; Caustics; Chelating Agents; Chronic Disease; Copper; Deferoxamine; Dimerca | 1969 |