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dimercaprol and Nervous System Disorders

dimercaprol has been researched along with Nervous System Disorders in 13 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Research Excerpts

ExcerptRelevanceReference
"The importance of arsenic poisoning by herbal preparations is discussed, as there are no known reports of their association."5.25Arsenic poisoning from anti-asthmatic herbal preparations. ( Seah, CS; Tay, CH, 1975)
"The importance of arsenic poisoning by herbal preparations is discussed, as there are no known reports of their association."1.25Arsenic poisoning from anti-asthmatic herbal preparations. ( Seah, CS; Tay, CH, 1975)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199011 (84.62)18.7374
1990's2 (15.38)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MOORE, DF1
FURMANSKI, AR1
DOBRINA, D1
Dawson, MA1
Chhuttani, PN1
Chawla, LS1
Sharma, TD1
de Francisci, G1
Magalini, SI1
Scheinberg, IH1
Sternlieb, I1
Oishi, T1
Hasegawa, E1
Murai, Y1
Zimmer, L1
Carter, DE2
Zimmer, LJ1
Tay, CH1
Seah, CS1
Cumings, JN1
Jenkins, RB1

Reviews

1 review available for dimercaprol and Nervous System Disorders

ArticleYear
[Lead poisoning].
    Recenti progressi in medicina, 1983, Volume: 74, Issue:6

    Topics: Adrenal Cortex Hormones; Calcium Gluconate; Dimercaprol; Edetic Acid; Gastrointestinal Diseases; Hem

1983

Other Studies

12 other studies available for dimercaprol and Nervous System Disorders

ArticleYear
BAL and malnutrition of the nervous system.
    British medical journal, 1947, Dec-13, Volume: 2, Issue:4536

    Topics: Central Nervous System Depressants; Dimercaprol; Malnutrition; Nervous System Diseases

1947
BAL therapy in infectious and metabolic neuropathies.
    The Journal of nervous and mental disease, 1954, Volume: 119, Issue:5

    Topics: Dimercaprol; Humans; Nervous System Diseases

1954
[IMMUNITARY MODIFICATIONS INDUCED BY 2-3 DIMERCAPTOPROPANOL IN CHRONIC DISEASES OF THE NERVOUS SYSTEM].
    Clinica (Bologna, Italy), 1964, Volume: 23

    Topics: Central Nervous System Depressants; Chronic Disease; Dimercaprol; Immunity; Nervous System Diseases;

1964
Arsenic polyneuropathy.
    The Journal of the Kentucky Medical Association, 1967, Volume: 65, Issue:8

    Topics: Adult; Arsenic Poisoning; Dimercaprol; Humans; Male; Nervous System Diseases

1967
Arsenical neuropathy.
    Neurology, 1967, Volume: 17, Issue:3

    Topics: Adult; Aged; Arsenic Poisoning; Dimercaprol; Electrocardiography; Female; Follow-Up Studies; Humans;

1967
Treatment of the neurologic manifestations of Wilson's disease.
    Archives of neurology, 1995, Volume: 52, Issue:4

    Topics: Dimercaprol; Hepatolenticular Degeneration; Humans; Molybdenum; Nervous System Diseases; Penicillami

1995
Sulfhydryl drugs reduce neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the mouse.
    Journal of neural transmission. Parkinson's disease and dementia section, 1993, Volume: 6, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striat

1993
Effects of complexing treatment administered with the onset of methyl mercury neurotoxic signs.
    Toxicology and applied pharmacology, 1979, Volume: 51, Issue:1

    Topics: Animals; Body Weight; Chelating Agents; Dimercaprol; Female; Glucuronidase; Mercury; Methylmercury C

1979
The efficacy of 2,3-dimercaptopropanol and D-penicillamine on methyl mercury induced neurological signs and weight loss.
    Life sciences, 1978, Sep-11, Volume: 23, Issue:10

    Topics: Animals; Body Weight; Dimercaprol; Female; Methylmercury Compounds; Nervous System Diseases; Penicil

1978
Arsenic poisoning from anti-asthmatic herbal preparations.
    The Medical journal of Australia, 1975, Sep-13, Volume: 2, Issue:11

    Topics: Adolescent; Adult; Arsenic; Arsenic Poisoning; Asthma; Child; Child, Preschool; Dimercaprol; Female;

1975
Inborn errors of metabolism in neurology (Wilson's disease, Refsum's disease and lipidoses).
    Proceedings of the Royal Society of Medicine, 1971, Volume: 64, Issue:3

    Topics: Adolescent; Adult; Cerebral Cortex; Ceruloplasmin; Cholesterol; Copper; Dimercaprol; Fatty Acids; Fe

1971
Inorganic arsenic and the nervous system.
    Brain : a journal of neurology, 1966, Volume: 89, Issue:3

    Topics: Adolescent; Adult; Aged; Arsenic Poisoning; Child; Child, Preschool; Diagnosis, Differential; Dimerc

1966