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dimercaprol and Nephrotic Syndrome

dimercaprol has been researched along with Nephrotic Syndrome in 7 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ENNEKING, JH1
PETERS, HJ1
SHER, DA1
NEFF, WS1
WARREN, DE1
Klepikov, PV1
Nikolaev, AIu1
VarshavskiÄ­, VA1
Pal'tsev, MA1
Androsova, SO1
Gaultier, M1
Fournier, E1
Gervais, P1
Morel-Maroger, L1
Bismuth, C1
Rain, JD1
Kaneda, H1
Nishio, M1
Kurokawa, K1
Mimura, N1

Reviews

1 review available for dimercaprol and Nephrotic Syndrome

ArticleYear
[Nephrotic syndrome--rare complication of gold therapy].
    Terapevticheskii arkhiv, 1983, Volume: 55, Issue:10

    Topics: Anti-Inflammatory Agents; Dimercaprol; Female; Gold; Humans; Middle Aged; Nephrotic Syndrome; Organo

1983

Other Studies

6 other studies available for dimercaprol and Nephrotic Syndrome

ArticleYear
[NEPHROTIC SYNDROME AFTER PROLONGED USE OF A MERCURIAL OINTMENT. MERCURY EXCRETION DURING TREATMENT WITH BAL AND N-ACETYL-DL-PENICILLAMINE].
    Nederlands tijdschrift voor geneeskunde, 1964, Feb-08, Volume: 108

    Topics: Adolescent; Body Fluids; Dimercaprol; Mercury; Mercury Poisoning; Nephrotic Syndrome; Ointments; Pen

1964
MERCURY INTOXICATION AND THE NEPHROTIC SYNDROME. A REPORT OF THREE CASES IN ONE FAMILY.
    Minnesota medicine, 1964, Volume: 47

    Topics: Adrenal Cortex Hormones; Child; Dimercaprol; Drug Therapy; Mercury; Mercury Poisoning; Minnesota; Ne

1964
NEPHROTIC SYNDROME CAUSED BY PROTIODIDE OF MERCURY.
    Archives of dermatology, 1965, Volume: 91

    Topics: Child; Dimercaprol; Drug Therapy; Humans; Mercury; Mercury Poisoning; Nephrotic Syndrome; Prednisone

1965
Treatment of lead poisoning.
    The Medical letter on drugs and therapeutics, 1972, Feb-04, Volume: 14, Issue:3

    Topics: Administration, Oral; Adult; Anemia, Aplastic; Chelating Agents; Child; Dimercaprol; Edetic Acid; En

1972
[2 cases of nephrotic syndrome in a thermometer factory].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1968, Volume: 119, Issue:1

    Topics: Adult; Dimercaprol; Female; Humans; Mercury Poisoning; Nephrotic Syndrome; Occupational Diseases

1968
[Case of nephrotic syndrome caused by gold preparations].
    Nihon rinsho. Japanese journal of clinical medicine, 1968, Volume: 26, Issue:5

    Topics: Asthma; Biopsy; Dimercaprol; Gold; Humans; Kidney; Male; Middle Aged; Nephrotic Syndrome

1968