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dimercaprol and Neoplasms

dimercaprol has been researched along with Neoplasms in 4 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Treatment with dimercaprol remains the mainstay of therapy, and early treatment is necessary to prevent irreversible complications."1.26Arsenic poisoning. ( Schoolmeester, WL; White, DR, 1980)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BECK, LV1
PABLO BOSQ, FJ1
SANCHEZ CABELLERO, HJ1
FRANK, G1
Schoolmeester, WL1
White, DR1

Other Studies

4 other studies available for dimercaprol and Neoplasms

ArticleYear
Action of BAL on the tumor-damaging potency of certain trivalent arsenic compounds.
    Journal of the National Cancer Institute, 1952, Volume: 13, Issue:3

    Topics: Animals; Arsenicals; Dimercaprol; Neoplasms; Neoplasms, Experimental

1952
[Dimercaprol (BAL) in the treatment of basal cell cutaneous epitheliomas, with special application for palpebral localizations].
    El Dia medico, 1954, Dec-13, Volume: 26, Issue:91

    Topics: Carcinoma, Basal Cell; Dimercaprol; Eyelid Neoplasms; Eyelids; Face; Facial Neoplasms; Humans; Neopl

1954
A case of industrial arsenical cancer occurring for the first time in Hungary and a comprehensive analysis of it.
    Acta dermato-venereologica, 1950, Volume: 30, Issue:2

    Topics: Arsenic; Arsenicals; Dimercaprol; Humans; Hungary; Industry; Male; Neoplasms; Occupational Diseases;

1950
Arsenic poisoning.
    Southern medical journal, 1980, Volume: 73, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Arsenates; Arsenic; Arsenic Poisoning; Child, Preschool; Chronic D

1980