dimercaprol has been researched along with Muscle Contraction in 8 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 6 (75.00) | 18.7374 |
1990's | 2 (25.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ashizawa, N | 1 |
Okumura, H | 1 |
Kobayashi, F | 1 |
Aotsuka, T | 1 |
Asakura, R | 1 |
Arai, K | 1 |
Ashikawa, N | 1 |
Matsuura, A | 1 |
Henriksen, EJ | 1 |
Schneider, MC | 1 |
Ritter, LS | 1 |
Auerswald, W | 1 |
Doleschel, W | 1 |
McCormick, JT | 1 |
Senior, J | 1 |
Caciagli, F | 1 |
Amato, G | 1 |
Bertelli, A | 1 |
Hall, DW | 1 |
Bonta, IL | 1 |
Camargo, A | 1 |
Ferreira, SH | 1 |
Dolovich, J | 1 |
Back, N | 1 |
Arbesman, CE | 1 |
8 other studies available for dimercaprol and Muscle Contraction
Article | Year |
---|---|
Inhibitory activities of metal chelators on endothelin-converting enzyme. II. In vivo studies.
Topics: Animals; Aorta, Thoracic; Aspartic Acid Endopeptidases; Blood Pressure; Chelating Agents; Death, Sud | 1994 |
Regulation of contraction-stimulated system A amino acid uptake in skeletal muscle: role of vicinal sulfhydryls.
Topics: Amino Acids; Animals; Arsenicals; beta-Alanine; Dimercaprol; Electric Stimulation; Insulin; Kinetics | 1993 |
On the potentiation of kinins by sulfhydrylic compounds.
Topics: Angiotensin II; Animals; beta-Aminoethyl Isothiourea; Bradykinin; Cysteamine; Cysteine; Dimercaprol; | 1967 |
Plasma kinin and kininogen levels in the female rat during the oestrous cycle, pregnancy, parturition and the puerperium.
Topics: Animals; Biological Assay; Blood Volume; Bradykinin; Chymotrypsin; Dimercaprol; Estrus; Female; In V | 1974 |
Substances released by trypsin potentiating bradykinin action on smooth muscle.
Topics: Acetylcholine; Animals; Bradykinin; Dimercaprol; Dose-Response Relationship, Drug; Drug Synergism; G | 1974 |
Potentiation of the biphasic bradykinin response of the guinea-pig ileum.
Topics: Acetylcholine; Animals; Bradykinin; Cysteine; Dimercaprol; Drug Synergism; Glycerol; Guinea Pigs; Il | 1974 |
Action of bradykinin potentiating factor (BPF) and dimercaprol (BAL) on the responses to bradykinin of isolated preparations of rat intestines.
Topics: Animals; Bradykinin; Depression, Chemical; Dimercaprol; Duodenum; Ileum; In Vitro Techniques; Muscle | 1971 |
Kinin-like activity in nasal secretions of allergic patients.
Topics: Aerosols; Carboxypeptidases; Chymotrypsin; Dimercaprol; Endopeptidases; Humans; Kinins; Mucus; Muscl | 1970 |