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dimercaprol and Muscle Contraction

dimercaprol has been researched along with Muscle Contraction in 8 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's2 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ashizawa, N1
Okumura, H1
Kobayashi, F1
Aotsuka, T1
Asakura, R1
Arai, K1
Ashikawa, N1
Matsuura, A1
Henriksen, EJ1
Schneider, MC1
Ritter, LS1
Auerswald, W1
Doleschel, W1
McCormick, JT1
Senior, J1
Caciagli, F1
Amato, G1
Bertelli, A1
Hall, DW1
Bonta, IL1
Camargo, A1
Ferreira, SH1
Dolovich, J1
Back, N1
Arbesman, CE1

Other Studies

8 other studies available for dimercaprol and Muscle Contraction

ArticleYear
Inhibitory activities of metal chelators on endothelin-converting enzyme. II. In vivo studies.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:2

    Topics: Animals; Aorta, Thoracic; Aspartic Acid Endopeptidases; Blood Pressure; Chelating Agents; Death, Sud

1994
Regulation of contraction-stimulated system A amino acid uptake in skeletal muscle: role of vicinal sulfhydryls.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:4

    Topics: Amino Acids; Animals; Arsenicals; beta-Alanine; Dimercaprol; Electric Stimulation; Insulin; Kinetics

1993
On the potentiation of kinins by sulfhydrylic compounds.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 168, Issue:1

    Topics: Angiotensin II; Animals; beta-Aminoethyl Isothiourea; Bradykinin; Cysteamine; Cysteine; Dimercaprol;

1967
Plasma kinin and kininogen levels in the female rat during the oestrous cycle, pregnancy, parturition and the puerperium.
    British journal of pharmacology, 1974, Volume: 50, Issue:2

    Topics: Animals; Biological Assay; Blood Volume; Bradykinin; Chymotrypsin; Dimercaprol; Estrus; Female; In V

1974
Substances released by trypsin potentiating bradykinin action on smooth muscle.
    Pharmacological research communications, 1974, Volume: 6, Issue:4

    Topics: Acetylcholine; Animals; Bradykinin; Dimercaprol; Dose-Response Relationship, Drug; Drug Synergism; G

1974
Potentiation of the biphasic bradykinin response of the guinea-pig ileum.
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 207, Issue:2

    Topics: Acetylcholine; Animals; Bradykinin; Cysteine; Dimercaprol; Drug Synergism; Glycerol; Guinea Pigs; Il

1974
Action of bradykinin potentiating factor (BPF) and dimercaprol (BAL) on the responses to bradykinin of isolated preparations of rat intestines.
    British journal of pharmacology, 1971, Volume: 42, Issue:2

    Topics: Animals; Bradykinin; Depression, Chemical; Dimercaprol; Duodenum; Ileum; In Vitro Techniques; Muscle

1971
Kinin-like activity in nasal secretions of allergic patients.
    International archives of allergy and applied immunology, 1970, Volume: 38, Issue:4

    Topics: Aerosols; Carboxypeptidases; Chymotrypsin; Dimercaprol; Endopeptidases; Humans; Kinins; Mucus; Muscl

1970