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dimercaprol and Mental Disorders

dimercaprol has been researched along with Mental Disorders in 9 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.

Research Excerpts

ExcerptRelevanceReference
"Acute arsenic poisoning is less frequent and it is most often lethal."1.33[A case of neuropathy mimicking Guillain-Barré syndrome after arsenic intoxication]. ( Defebvre, L; Destee, A; Devos, D; Hurtevent, JF; Perriol, MP; Saulnier, F; Tiffreau, V, 2006)
"Fifty-eight patients with Wilson's disease are reviewed, of whom 25 symptomatic patients experienced liver disease first and 28, brain disease."1.26Clinical spectrum of Wilson's disease (hepatolenticular degeneration). ( Dobyns, WB; Goldstein, NP; Gordon, H, 1979)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
PAYNE, RB1
BRADLEY, JE1
BALDWIN, RW1
MENON, G1
GULBRANDSEN, R1
WIGMOSTAD, K1
GRUNFELD, O1
PETERS, HA1
Perriol, MP1
Devos, D1
Hurtevent, JF1
Tiffreau, V1
Saulnier, F1
Destee, A1
Defebvre, L1
Dobyns, WB1
Goldstein, NP1
Gordon, H1
Greenberg, JO1
Tavolato, B1
De Zanche, L1

Other Studies

9 other studies available for dimercaprol and Mental Disorders

ArticleYear
The effects of drugs upon psychological efficiency.
    The Journal of aviation medicine, 1953, Volume: 24, Issue:6

    Topics: Aerospace Medicine; Aviation; Dimercaprol; Diphenhydramine; Medicine; Mental Disorders; Military Per

1953
The comparison of BAL (2, 3-dimercaptopropanol) and Ca EDTA (calcium ethylene diamine tetra acetate) in the treatment of lead encephalopathy.
    Bulletin. Georgetown University. Medical Center, 1957, Volume: 10, Issue:3

    Topics: Calcium, Dietary; Dimercaprol; Edetic Acid; Ethylenes; Humans; Lead Poisoning; Mental Disorders; Psy

1957
[Acute porphyria; 2 cases with distinctive neuropsychiatric symptoms treated with BAL].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1958, May-01, Volume: 78, Issue:9

    Topics: Dimercaprol; Mental Disorders; Porphyria, Acute Intermittent; Porphyrias

1958
THALLIUM POISONING TREATED WITH BAL.
    The New England journal of medicine, 1963, Nov-21, Volume: 269

    Topics: Dimercaprol; Heavy Metal Poisoning; Mental Disorders; Metals, Heavy; Poisoning; Psychotic Disorders;

1963
Porphyric psychosis and chelation therapy.
    Recent advances in biological psychiatry, 1961, Volume: 4

    Topics: Animals; Chelation Therapy; Dimercaprol; Edetic Acid; Humans; Mental Disorders; Porifera; Porphyrias

1961
[A case of neuropathy mimicking Guillain-Barré syndrome after arsenic intoxication].
    Revue neurologique, 2006, Volume: 162, Issue:3

    Topics: Acute Kidney Injury; Arsenic Poisoning; Chelating Agents; Chelation Therapy; Diagnosis, Differential

2006
Clinical spectrum of Wilson's disease (hepatolenticular degeneration).
    Mayo Clinic proceedings, 1979, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Brain Diseases; Child; Copper; Cornea; Dimercaprol; Female; Hepatolenticular Dege

1979
The neurological effects of methyl bromide poisoning.
    IMS, Industrial medicine and surgery, 1971, Volume: 40, Issue:4

    Topics: Adult; Amobarbital; Brain Diseases; Bromine; Cerebellar Ataxia; Diazepam; Dimercaprol; Electroenceph

1971
[Therapeutic considerations on Wilson's disease].
    Giornale di psichiatria e di neuropatologia, 1966, Volume: 94, Issue:4

    Topics: Adult; Dimercaprol; Hepatolenticular Degeneration; Humans; Male; Mental Disorders; Movement Disorder

1966