dimercaprol has been researched along with Leukopenia in 3 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
Leukopenia: A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty patients with a significant rheumatoid arthritis (RA) were treated with gold salts for 6 months to 4 years." | 5.05 | [Comparative analysis of the effectiveness and tolerance of chrysanol and myochrysine in patients with rheumatoid arthritis (preliminary report)]. ( Slobodina, GA, 1985) |
| "Lung injury following intravenous oleic acid is characterized by pulmonary edema, leukopenia and hypoxemia." | 3.67 | Oleic acid-induced pulmonary injury in rats: potential role of sulfidopeptide leukotrienes. ( Ball, HA; Cook, JA; Halushka, PV; Hsu, CY; Spicer, KM, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Devlin, HB | 1 |
| Sudlow, M | 1 |
| Ball, HA | 1 |
| Cook, JA | 1 |
| Spicer, KM | 1 |
| Hsu, CY | 1 |
| Halushka, PV | 1 |
| Slobodina, GA | 1 |
1 trial available for dimercaprol and Leukopenia
| Article | Year |
|---|---|
[Comparative analysis of the effectiveness and tolerance of chrysanol and myochrysine in patients with rheumatoid arthritis (preliminary report)].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Clinical Trials as Topic; Dimercaprol; Drug E | 1985 |
2 other studies available for dimercaprol and Leukopenia
| Article | Year |
|---|---|
Peripheral mercury embolization occurring during arterial blood sampling.
Topics: Adult; Blood Specimen Collection; Dimercaprol; Humans; Leukopenia; Male; Mercury; Mercury Poisoning; | 1967 |
Oleic acid-induced pulmonary injury in rats: potential role of sulfidopeptide leukotrienes.
Topics: Acetophenones; Animals; Capillary Permeability; Dimercaprol; Leukopenia; Leukotriene B4; Leukotriene | 1988 |