dimercaprol has been researched along with Leukemia, Promyelocytic, Acute in 1 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
Leukemia, Promyelocytic, Acute: An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present a rare case of a woman aged 62 years with refractory acute promyelocytic leukemia treated with arsenic trioxide leading to progressive, multilevel cardiac conduction block." | 3.79 | Cardiac conduction block at multiple levels caused by arsenic trioxide therapy. ( Angaran, P; Gula, LJ; Kathirgamanathan, K; Lazo-Langner, A, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kathirgamanathan, K | 1 |
| Angaran, P | 1 |
| Lazo-Langner, A | 1 |
| Gula, LJ | 1 |
1 other study available for dimercaprol and Leukemia, Promyelocytic, Acute
| Article | Year |
|---|---|
Cardiac conduction block at multiple levels caused by arsenic trioxide therapy.
Topics: Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Chelating Agents; Dimercaprol; Electrocardiogra | 2013 |