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dimercaprol and Kidney Failure

dimercaprol has been researched along with Kidney Failure in 7 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.

Research Excerpts

ExcerptRelevanceReference
"Inorganic mercury poisoning is uncommon, but when it occurs it can result in severe, life threatening features and acute renal failure."1.36Accidental inorganic mercury chloride poisoning in a 2-year old child. ( Khadwal, A; Kumar, R; Singhi, S; Verma, S, 2010)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cameron, GR1
Burgess, F1
Trenwith, VS1
Verma, S1
Kumar, R1
Khadwal, A1
Singhi, S1
SANCHEZ-SICILIA, L1
SETO, DS1
NAKAMOTO, S1
KOLFF, WJ1
SITBON, A1
VALEK, A1
Hantson, P1
Lievens, M1
Mahieu, P1
Kamijo, Y1
Soma, K1
Yosimura, K1
Ohwada, T1

Other Studies

7 other studies available for dimercaprol and Kidney Failure

ArticleYear
The possibility of toxic effects from 2:3-dimercaptopropanol in conditions of impaired renal or hepatic function.
    British journal of pharmacology and chemotherapy, 1947, Volume: 2, Issue:1

    Topics: Dimercaprol; Hepatic Insufficiency; Humans; Renal Insufficiency; Sulfhydryl Compounds

1947
Accidental inorganic mercury chloride poisoning in a 2-year old child.
    Indian journal of pediatrics, 2010, Volume: 77, Issue:10

    Topics: Chelating Agents; Child, Preschool; Dimercaprol; Humans; Male; Mercuric Chloride; Poisoning; Renal I

2010
ACUTE MERCURIAL INTOXICATION TREATED BY HEMODIALYSIS.
    Annals of internal medicine, 1963, Volume: 59

    Topics: Acute Kidney Injury; Dimercaprol; Infusions, Parenteral; Kidney; Kidneys, Artificial; Mercury Poison

1963
[RENAL INVOLVEMENT DURING ACUTE POISONINGS].
    Maroc medical, 1964, Volume: 43

    Topics: Acute Kidney Injury; Dimercaprol; Kidney; Kidneys, Artificial; Poisoning; Renal Insufficiency; Thiom

1964
ACUTE RENAL INSUFFICIENCY IN INTOXICATIONS WITH MERCURY COMPOUNDS. II. TREATMENT AND PROGNOSIS.
    Acta medica Scandinavica, 1965, Volume: 177

    Topics: Acute Kidney Injury; Antidotes; Anuria; Dimercaprol; Gastric Lavage; Kidneys, Artificial; Mercury Co

1965
Accidental ingestion of a zinc and copper sulfate preparation.
    Journal of toxicology. Clinical toxicology, 1996, Volume: 34, Issue:6

    Topics: Aged; Aged, 80 and over; Cardiovascular System; Chelating Agents; Copper Sulfate; Digestive System;

1996
Acute mercuric chloride poisoning: effect of co-ingested milk on outcome and continued hyperamylasemia.
    Veterinary and human toxicology, 2001, Volume: 43, Issue:5

    Topics: Administration, Oral; Aged; Aged, 80 and over; Animals; Binding Sites; Chelating Agents; Dimercaprol

2001