dimercaprol has been researched along with Kidney Diseases in 13 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Analysis is made of the results of the treatment with parenteral (crysanol and myochrysine) and oral (ridaura) gold drugs as well as with small doses of D-penicillamine (DP) of patients suffering from rheumatoid arthritis with the signs of nephropathy." | 5.07 | [A comparative evaluation of parenteral and oral preparations of gold and D-penicillamine in the treatment of rheumatoid nephropathy]. ( Chichasova, NV; Kanevskaia, MZ; Krel', AA; Krel', OV; Slobodina, GA; Varshavskiĭ, VA, 1991) |
| "Although treatment has been well defined for childhood lead poisoning and for industrial lead exposure, the treatment of lead nephropathy has been poorly studied." | 3.65 | Chelation therapy in lead nephropathy. ( Morgan, JM, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (92.31) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| CHIODI, H | 1 |
| SAMMARTINO, RA | 1 |
| DOOLAN, PD | 1 |
| HESS, WC | 1 |
| KYLE, LH | 1 |
| POLUBOIARINOVA, ZI | 1 |
| de Francisci, G | 1 |
| Magalini, SI | 1 |
| Morgan, JM | 1 |
| Laconi, A | 1 |
| Buscemi, M | 1 |
| Cardinale, A | 1 |
| De Simone, GF | 1 |
| Pasqualino, A | 1 |
| Tessitore, V | 1 |
| Liniecki, J | 1 |
| Surma, M | 1 |
| Mlodkowska, E | 1 |
| Ogiński, M | 2 |
| Rembelska, M | 1 |
| Chichasova, NV | 1 |
| Kanevskaia, MZ | 1 |
| Slobodina, GA | 1 |
| Varshavskiĭ, VA | 1 |
| Krel', OV | 1 |
| Krel', AA | 1 |
| Kojima, S | 1 |
| Shimada, H | 1 |
| Kiyozumi, M | 1 |
| Malaise, MG | 1 |
| Davin, JC | 1 |
| Mahieu, PR | 1 |
| Franchimont, P | 1 |
| Flora, SS | 1 |
| Tandon, SK | 1 |
| Viol, GW | 1 |
| Keane, PM | 1 |
| Speed, JF | 1 |
| Smith, EK | 1 |
1 review available for dimercaprol and Kidney Diseases
| Article | Year |
|---|---|
[Lead poisoning].
Topics: Adrenal Cortex Hormones; Calcium Gluconate; Dimercaprol; Edetic Acid; Gastrointestinal Diseases; Hem | 1983 |
1 trial available for dimercaprol and Kidney Diseases
| Article | Year |
|---|---|
[A comparative evaluation of parenteral and oral preparations of gold and D-penicillamine in the treatment of rheumatoid nephropathy].
Topics: Administration, Oral; Antirheumatic Agents; Arthritis, Rheumatoid; Auranofin; Dimercaprol; Drug Ther | 1991 |
11 other studies available for dimercaprol and Kidney Diseases
| Article | Year |
|---|---|
Nephrotoxic and renotropic effects of lead on white rats and its prevention by B.A.L.
Topics: Animals; Dimercaprol; Kidney Diseases; Lead; Lead Poisoning; Rats | 1947 |
Acute renal insufficiency due to bichloride of mercury; observations on gastrointestinal hemorrhage and BAL therapy.
Topics: Acute Kidney Injury; Dimercaprol; Gastrointestinal Hemorrhage; Gastrointestinal Tract; Hemorrhage; H | 1953 |
[THE ACTION OF UNITHIOL ON RENAL FUNCTION IN DOGS SUBJECTED TO IONIZING RADIATIONS].
Topics: Animals; Dimercaprol; Dogs; Kidney Diseases; Pharmacology; Radiation Injuries; Radiation Injuries, E | 1963 |
Chelation therapy in lead nephropathy.
Topics: Acute Kidney Injury; Administration, Oral; Chelating Agents; Creatinine; Dimercaprol; Drug Eruptions | 1975 |
[Protective effect of complexogenic drugs (BAL, alpha-mercaptopropionyl-glycine) on some enzyme activities of the kidney of rats treated with chlormerodrin-Hg197. Histochemical studies].
Topics: Acetylglucosaminidase; Adenosine Triphosphatases; Amino Acids, Sulfur; Animals; Chlormerodrin; Dimer | 1975 |
99MTechnetium-Unithiol complex, a new pharmaceutical for kidney scintigraphy. II. Comparison of renal scintigrams in man, obtained by means of 197Hg-chlormerodrin or 99mTc-Unithiol complex.
Topics: Adult; Aged; Chlormerodrin; Dimercaprol; Female; Humans; Kidney Diseases; Male; Mercury Radioisotope | 1977 |
99mTechnetium-unithiol complex, a new pharmaceutical for kidney scintigraphy.
Topics: Animals; Dimercaprol; Dogs; Kidney Diseases; Rabbits; Radionuclide Imaging; Rats; Technetium; Unithi | 1976 |
Comparative effects of chelating agents on distribution, excretion, and renal toxicity of inorganic mercury in rats.
Topics: Animals; Bile; Chelating Agents; Dimercaprol; Glucose; Kidney Diseases; Male; Mercury; Mercury Radio | 1989 |
Elevated antigalactosyl antibody titers reflect renal injury after gold or D-penicillamine in rheumatoid arthritis.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Antibody Formation; Antibody Specificit | 1986 |
Chelation in metal intoxication. XV: Influence of dimercaptopropane sulphonate (DMPS) on lead poisoned rats with normal or damaged kidneys.
Topics: Animals; Chelating Agents; Dimercaprol; Kidney Diseases; Lead Poisoning; Male; Organometallic Compou | 1985 |
Assay of plasma renin activity using commercially available reagents.
Topics: Angiotensin II; Binding Sites, Antibody; Blood Proteins; Charcoal; Dialysis; Dimercaprol; Drug Stabi | 1972 |