dimercaprol has been researched along with Jaundice in 6 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
Jaundice: A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The clinical signs were jaundice and amaurosis." | 1.27 | Icterus and amaurosis caused by lead poisoning in a cynomolgus monkey (Macaca fascicularis). ( Dorrestein, GM; Lumeij, JT, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grasso, IA | 1 |
| Blattner, MR | 1 |
| Short, T | 1 |
| Downs, JW | 1 |
| CERESA, C | 1 |
| JAKOBIEC, M | 1 |
| KRAUSS-ZAKI, J | 1 |
| JANOVICS, T | 1 |
| TAKO, J | 1 |
| Lumeij, JT | 1 |
| Dorrestein, GM | 1 |
| Blattner, RJ | 1 |
6 other studies available for dimercaprol and Jaundice
| Article | Year |
|---|---|
Severe Systemic Lead Toxicity Resulting From Extra-Articular Retained Shrapnel Presenting as Jaundice and Hepatitis: A Case Report and Review of the Literature.
Topics: Abdominal Pain; Adult; Chelating Agents; Chelation Therapy; Constipation; Dimercaprol; Foreign Bodie | 2017 |
[B.A.L. in therapy of jaundice caused by hepatitis].
Topics: Dimercaprol; Hepatitis; Humans; Jaundice | 1952 |
[Treatment of parenchymatous jaundice with BAL].
Topics: Communicable Diseases; Dimercaprol; Hepatitis; Hepatitis A; Jaundice | 1954 |
[Use of BAL in diffuse parenchymal disease of the liver].
Topics: Arsphenamine; Dimercaprol; Hepatitis; Hepatitis A; Jaundice | 1950 |
Icterus and amaurosis caused by lead poisoning in a cynomolgus monkey (Macaca fascicularis).
Topics: Animals; Blindness; Dimercaprol; Jaundice; Lead Poisoning; Macaca mulatta; Male; Monkey Diseases | 1986 |
Hemolytic anemia associated with Wilson's disease.
Topics: Adult; Anemia, Hemolytic; Ascites; Child; Copper; Cornea; Diet Therapy; Dimercaprol; Edetic Acid; Fe | 1967 |