dimercaprol has been researched along with Innate Inflammatory Response in 9 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Song, HY | 1 |
| Chen, F | 1 |
| Park, HR | 1 |
| Han, JM | 1 |
| Ji, HJ | 1 |
| Byun, EB | 1 |
| Kwon, Y | 1 |
| Kim, MK | 1 |
| Ahn, KB | 1 |
| Seo, HS | 1 |
| Shlykova, O | 1 |
| Izmailova, O | 1 |
| Kabaliei, A | 1 |
| Palchyk, V | 1 |
| Shynkevych, V | 1 |
| Kaidashev, I | 1 |
| McElroy, PB | 1 |
| Sri Hari, A | 1 |
| Day, BJ | 1 |
| Patel, M | 1 |
| ZAROWITZ, H | 1 |
| NELSON, L | 1 |
| Lapenna, D | 1 |
| De Gioia, S | 1 |
| Ciofani, G | 1 |
| Mezzetti, A | 1 |
| Consoli, A | 1 |
| Di Ilio, C | 1 |
| Cuccurullo, F | 1 |
| Hantson, P | 1 |
| Lievens, M | 1 |
| Mahieu, P | 1 |
| McElvaney, NG | 1 |
| Nakamura, H | 1 |
| Birrer, P | 1 |
| Hébert, CA | 1 |
| Wong, WL | 1 |
| Alphonso, M | 1 |
| Baker, JB | 1 |
| Catalano, MA | 1 |
| Crystal, RG | 1 |
| Harmsen, AG | 1 |
| Pham Huy, D | 1 |
| Roch-Arveiller, M | 1 |
| Muntaner, O | 1 |
| Giroud, JP | 1 |
9 other studies available for dimercaprol and Innate Inflammatory Response
| Article | Year |
|---|---|
Low-dose radiation therapy suppresses viral pneumonia by enhancing broad-spectrum anti-inflammatory responses via transforming growth factor-β production.
Topics: Animals; Arthritis, Rheumatoid; COVID-19; Cytokines; Dimercaprol; Inflammation; Mice; Pneumonia, Vir | 2023 |
PPARG stimulation restored lung mRNA expression of core clock, inflammation- and metabolism-related genes disrupted by reversed feeding in male mice.
Topics: Animals; Dimercaprol; Inflammation; Interleukin-6; Lung; Male; Mice; Pioglitazone; PPAR gamma; RNA, | 2023 |
Post-translational Activation of Glutamate Cysteine Ligase with Dimercaprol: A NOVEL MECHANISM OF INHIBITING NEUROINFLAMMATION
Topics: Animals; Cell Line; Cytokines; Dimercaprol; Enzyme Activation; Glutamate-Cysteine Ligase; Glutathion | 2017 |
A case of acute BAL toxicity during treatment of gold glossitis.
Topics: Dimercaprol; Glossitis; Gold; Humans; Inflammation; Tongue | 1949 |
Hypochlorous acid-induced zinc release from thiolate bonds: a potential protective mechanism towards biomolecules oxidant damage during inflammation.
Topics: alpha-Linolenic Acid; Animals; Antioxidants; Deoxyribose; Dimercaprol; Humans; Hydrogen Peroxide; Hy | 1994 |
Accidental ingestion of a zinc and copper sulfate preparation.
Topics: Aged; Aged, 80 and over; Cardiovascular System; Chelating Agents; Copper Sulfate; Digestive System; | 1996 |
Modulation of airway inflammation in cystic fibrosis. In vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor.
Topics: Adult; Aerosols; Cystic Fibrosis; Dimercaprol; Epithelium; Female; Humans; Inflammation; Interleukin | 1992 |
Role of alveolar macrophages in lipopolysaccharide-induced neutrophil accumulation.
Topics: Aerosols; Animals; Cell Movement; Dimercaprol; Inflammation; Lipopolysaccharides; Macrophages; Mice; | 1988 |
In vitro and in vivo effects of gold salts on chemotaxis and random migration of rat polymorphonuclear leucocytes.
Topics: Animals; Auranofin; Aurothioglucose; Calcium Pyrophosphate; Cell Movement; Chemotaxis, Leukocyte; Di | 1985 |