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dimercaprol and Hypersensitivity

dimercaprol has been researched along with Hypersensitivity in 4 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.

Research Excerpts

ExcerptRelevanceReference
"The arylsulfatase activity and histamine concentration of bronchoalveolar lavage fluid (BALF) were examined in patients with bronchial asthma in relation to the eosinophil count and asthma type (atopic and non-atopic)."3.67Eosinophilic leucocytes and arylsulfatase activity in bronchoalveolar lavage fluid of patients with bronchial asthma. ( Araki, H; Kimura, I; Kitani, H; Oki, K; Sudo, M; Takahashi, K; Tanizaki, Y; Tsuji, M, 1988)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
PASTINSZKY, E1
SIMON, N1
HASSELMANN, CM1
RICHTER, R1
BERGMANN, A1
EILLES, W1
JOHNE, HO1
Andersson, P1
Brange, C1
von Kogerer, B1
Sonmark, B1
Stahre, G1
Tanizaki, Y1
Sudo, M1
Kitani, H1
Araki, H1
Oki, K1
Tsuji, M1
Takahashi, K1
Kimura, I1

Other Studies

4 other studies available for dimercaprol and Hypersensitivity

ArticleYear
[Investigation of the sensitizing effect of BAL in the Schultz-Dale experiments].
    Acta dermato-venereologica, 1951, Volume: 31, Issue:1

    Topics: Dimercaprol; Humans; Hypersensitivity

1951
[Experimental and clinical observations on necrosis of muscle following injection of BAL and sulfactin (Homburg), and its relation to the Sanarelli-Shwartzman phenomenon].
    Archiv fur Dermatologie und Syphilis, 1951, Volume: 192, Issue:6

    Topics: Dimercaprol; Humans; Hypersensitivity; Immune System Diseases; Muscles; Necrosis; Shwartzman Phenome

1951
Effect of glucocorticosteroid treatment on ovalbumin-induced IgE-mediated immediate and late allergic response in guinea pig.
    International archives of allergy and applied immunology, 1988, Volume: 87, Issue:1

    Topics: Anaphylaxis; Animals; Antigens; Bronchi; Bronchial Provocation Tests; Budesonide; Cromolyn Sodium; D

1988
Eosinophilic leucocytes and arylsulfatase activity in bronchoalveolar lavage fluid of patients with bronchial asthma.
    Acta medica Okayama, 1988, Volume: 42, Issue:4

    Topics: Adult; Arylsulfatases; Asthma; Dimercaprol; Eosinophils; Histamine; Humans; Hypersensitivity; Immuno

1988