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dimercaprol and Heart Failure

dimercaprol has been researched along with Heart Failure in 2 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KRAYER, O1
FARAH, A1
SUSSMAN, RM1
SCHACK, JA1

Other Studies

2 other studies available for dimercaprol and Heart Failure

ArticleYear
Action of cysteine and of dimercaptopropanol in heart failure caused by sodium bismuth tartrate.
    Federation proceedings, 1948, Volume: 7, Issue:1 Pt 1

    Topics: Bismuth; Cysteine; Dimercaprol; Heart Failure; Humans; Organometallic Compounds; Sodium; Tartrates

1948
BAL inhibition of mercurial diuresis in congestive heart failure.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1947, Volume: 66, Issue:1

    Topics: Dimercaprol; Diuresis; Diuretics; Heart Arrest; Heart Failure; Humans

1947