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dimercaprol and Gastrointestinal Hemorrhage

dimercaprol has been researched along with Gastrointestinal Hemorrhage in 3 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.

Research Excerpts

ExcerptRelevanceReference
"Cimetidine was administered at a low dose that did not inhibit hydrogen ion secretion."1.27Role of the adrenal cortex in gastric mucosal protection by prostaglandins, sulfhydryls, and cimetidine in the rat. ( Brzozowski, T; Frankel, PW; Gallagher, GT; Horner, HC; Konturek, SJ; Szabo, S; Trier, JS; Underwood, RH, 1983)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DOOLAN, PD1
HESS, WC1
KYLE, LH1
Szabo, S1
Gallagher, GT1
Horner, HC1
Frankel, PW1
Underwood, RH1
Konturek, SJ1
Brzozowski, T1
Trier, JS1
Fairbanks, VF1

Other Studies

3 other studies available for dimercaprol and Gastrointestinal Hemorrhage

ArticleYear
Acute renal insufficiency due to bichloride of mercury; observations on gastrointestinal hemorrhage and BAL therapy.
    The New England journal of medicine, 1953, Aug-13, Volume: 249, Issue:7

    Topics: Acute Kidney Injury; Dimercaprol; Gastrointestinal Hemorrhage; Gastrointestinal Tract; Hemorrhage; H

1953
Role of the adrenal cortex in gastric mucosal protection by prostaglandins, sulfhydryls, and cimetidine in the rat.
    Gastroenterology, 1983, Volume: 85, Issue:6

    Topics: Adrenal Cortex; Animals; Cimetidine; Corticosterone; Dimercaprol; Female; Gastric Mucosa; Gastrointe

1983
Copper sulfate-induced hemolytic anemia. Inhibition of glucose-6-phosphate dehydrogenase and other possible etiologic mechanisms.
    Archives of internal medicine, 1967, Volume: 120, Issue:4

    Topics: Adult; Anemia, Hemolytic; Copper; Dimercaprol; Erythrocytes; Female; Gastrointestinal Hemorrhage; Gl

1967