dimercaprol has been researched along with Gastric Ulcer in 2 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sulfhydryl substances (cysteine, glutathione, cysteamine and BAL) provide protection against experimental gastric ulcer induced by indomethacin while being ulcerogenous in stress-ulcer." | 3.66 | On the cytoprotective action of sulfhydryl-containing substances. ( Bálint, GA; Varró, V, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bálint, GA | 1 |
| Varró, V | 1 |
| Peskar, BM | 1 |
| Ehrlich, K | 1 |
| Peskar, BA | 1 |
2 other studies available for dimercaprol and Gastric Ulcer
| Article | Year |
|---|---|
On the cytoprotective action of sulfhydryl-containing substances.
Topics: Animals; Cysteamine; Cysteine; Dimercaprol; Female; Gastric Mucosa; Glutathione; Rats; Rats, Inbred | 1982 |
Role of ATP-sensitive potassium channels in prostaglandin-mediated gastroprotection in the rat.
Topics: 16,16-Dimethylprostaglandin E2; Adaptation, Physiological; Adenosine Triphosphate; Administration, O | 2002 |