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dimercaprol and Gas Poisoning

dimercaprol has been researched along with Gas Poisoning in 12 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Gas Poisoning: Poisoning that results from exposure to gases such as CARBON MONOXIDE; NOBLE GASES; OXYGEN; or NATURAL GAS.

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199012 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GRAHAM, JD1
HOOD, J1
MANN, I1
PIRIE, A1
PULLINGER, BD1
ADLER, FH1
FRY, WE1
LEOPOLD, IH1
STOCKEN, LA2
THOMPSON, RH2
HARRISON, HE2
ORDWAY, NK1
DURLACHER, SH1
HUGHES, WF2
Jaeger, A1
Kopferschmitt, J1
Sauder, P1
Mantz, JM1
Greenberg, JO1
Teitelbaum, DT1
Kier, LC1

Other Studies

12 other studies available for dimercaprol and Gas Poisoning

ArticleYear
Actions of British anti-lewisite (2:3-dimercaptopropanol).
    British journal of pharmacology and chemotherapy, 1948, Volume: 3, Issue:1

    Topics: Dimercaprol; Gas Poisoning

1948
The treatment of lewisite and other arsenical vesicant lesions of the eyes of rabbits with British anti-lewisite (BAL).
    American journal of ophthalmology, 1947, Volume: 30, Issue:4

    Topics: Animals; Arsenicals; Dimercaprol; Eye; Eye Injuries; Gas Poisoning; Irritants; Rabbits

1947
Pathologic study of ocular lesions due to lewisite (B-chlorovinyldichloroarsine) changes with and without BAL (2,3-dimercaptopropanol) therapy.
    Archives of ophthalmology (Chicago, Ill. : 1929), 1947, Volume: 38, Issue:1

    Topics: Arsenicals; Dimercaprol; Eye; Eye Diseases; Gas Poisoning; Humans

1947
British anti-lewisite; arsenic and thiol excretion in animals after treatment of lewisite burns.
    The Biochemical journal, 1946, Volume: 40, Issue:4

    Topics: Animals; Arsenic; Arsenic Poisoning; Arsenicals; Burns; Dimercaprol; Gas Poisoning; Gases; Sulfhydry

1946
Poisoning from inhalation of the vapors of lewisite and phenyldichlorarsine; its pathology in the dog and treatment with 2,3-dimercaptopropanol (BAL).
    The Journal of pharmacology and experimental therapeutics, 1946, Volume: 87, Issue:4 Suppl

    Topics: Animals; Arsenic; Arsenicals; Dimercaprol; Dogs; Gas Poisoning; Gases

1946
The treatment by 2,3-dimercaptopropanol (BAL) of the systemic toxic effects of skin contamination with lewisite and phenyldichlorarsine.
    The Journal of pharmacology and experimental therapeutics, 1946, Volume: 87, Issue:4 Suppl

    Topics: Arsenic; Arsenicals; Dimercaprol; Gas Poisoning; Gases; Skin

1946
Treatment of lewisite burns of the eye with dimercaprol (BAL).
    Archives of ophthalmology (Chicago, Ill. : 1929), 1947, Volume: 37, Issue:1

    Topics: Arsenicals; Burns; Dimercaprol; Eye Injuries; Gas Poisoning; Humans

1947
Clinical uses of 2,3-dimercaptopropanol (BAL); the treatment of lewisite burns of the eye with BAL.
    The Journal of clinical investigation, 1946, Volume: 25, Issue:4

    Topics: Arsenic Poisoning; Arsenicals; Burns; Dimercaprol; Eye Injuries; Gas Poisoning

1946
Reactions of British anti-lewisite with arsenic and other metals in living systems.
    Physiological reviews, 1949, Volume: 29, Issue:2

    Topics: Arsenic; Dimercaprol; Gas Poisoning; Humans; Metals

1949
[Acute poisoning by inhalation of metallic vapors].
    Toxicological European research. Recherche europeenne en toxicologie, 1983, Volume: 5, Issue:5

    Topics: Adult; Aged; Dimercaprol; Female; Gas Poisoning; Humans; Male; Mercury Poisoning; Metals; Tin; Zinc

1983
The neurological effects of methyl bromide poisoning.
    IMS, Industrial medicine and surgery, 1971, Volume: 40, Issue:4

    Topics: Adult; Amobarbital; Brain Diseases; Bromine; Cerebellar Ataxia; Diazepam; Dimercaprol; Electroenceph

1971
Arsine poisoning. Report of five cases in the petroleum industry and a discussion of the indications for exchange transfusion and hemodialysis.
    Archives of environmental health, 1969, Volume: 19, Issue:1

    Topics: Acute Kidney Injury; Arsenic; Arsenic Poisoning; Arsenicals; Body Weight; Dimercaprol; Environmental

1969