dimercaprol has been researched along with Focal Neurologic Deficits in 10 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with dimercaprol remains the mainstay of therapy, and early treatment is necessary to prevent irreversible complications." | 1.26 | Arsenic poisoning. ( Schoolmeester, WL; White, DR, 1980) |
| "These data suggest that neurological manifestations occur frequently in those abusing leaded gasoline and that chelation therapy has an important place in their management." | 1.26 | The neurological manifestations of chronic inhalation of leaded gasoline. ( Boeckx, RL; Chow, PN; Rjani, KR; Seshia, SS, 1978) |
| "Treatment with dimercaprol produced a clinical improvement on the fourth day with a fall in blood mercury from 3." | 1.26 | [Encephalopathy due to organomercuric compounds]. ( Gil, R; Lefèvre, JP, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SMITH, HD | 1 |
| BOUDIN, G | 1 |
| PEPIN, B | 1 |
| LAURAS, A | 1 |
| BARRAINE, R | 1 |
| GRUNFELD, O | 1 |
| HINOSTROZA, G | 1 |
| Schoolmeester, WL | 1 |
| White, DR | 1 |
| Seshia, SS | 1 |
| Rjani, KR | 1 |
| Boeckx, RL | 1 |
| Chow, PN | 1 |
| Lefèvre, JP | 1 |
| Gil, R | 1 |
| Nagi, NA | 1 |
| Yassin, AK | 1 |
| Gharib, M | 1 |
| St Petery, J | 1 |
| Rennert, OM | 1 |
| Choi, H | 1 |
| Wolfson, S | 1 |
| Tavolato, B | 1 |
| De Zanche, L | 1 |
10 other studies available for dimercaprol and Focal Neurologic Deficits
| Article | Year |
|---|---|
PEDIATRIC LEAD POISONING.
Topics: Anemia; Anemia, Hypochromic; Blood Chemical Analysis; Body Fluids; Child; Dimercaprol; Edetic Acid; | 1964 |
[OUR EXPERIENCE IN THE TREATMENT OF WILSON'S DISEASE WITH PENICILLAMINE].
Topics: Adolescent; Copper; Dimercaprol; Edetic Acid; Hepatolenticular Degeneration; Humans; Neurologic Mani | 1963 |
THALLIUM POISONING.
Topics: Adolescent; Alopecia; Dimercaprol; Drug Therapy; Gastroenterology; Heavy Metal Poisoning; Metals, He | 1964 |
Arsenic poisoning.
Topics: Acute Disease; Adolescent; Adult; Arsenates; Arsenic; Arsenic Poisoning; Child, Preschool; Chronic D | 1980 |
The neurological manifestations of chronic inhalation of leaded gasoline.
Topics: Adolescent; Adult; Child; Child, Preschool; Dimercaprol; Edetic Acid; Electrocardiography; Electroen | 1978 |
[Encephalopathy due to organomercuric compounds].
Topics: Adult; Agricultural Workers' Diseases; Brain Diseases; Dimercaprol; Humans; Male; Mercury Poisoning; | 1977 |
Organic mercury poisoning in children.
Topics: Ataxia; Child; Diet; Dimercaprol; Edetic Acid; Female; Fungicides, Industrial; Hemoglobins; Humans; | 1974 |
Unusual problems tend to appear in crops.
Topics: Adult; Biopsy; Ceruloplasmin; Child; Diagnosis, Differential; Diet; Dimercaprol; Eye Manifestations; | 1971 |
Arsenic poisoning in childhood.
Topics: Accidents, Home; Arsenic; Arsenic Poisoning; Blood Chemical Analysis; Child, Preschool; Dimercaprol; | 1970 |
[Therapeutic considerations on Wilson's disease].
Topics: Adult; Dimercaprol; Hepatolenticular Degeneration; Humans; Male; Mental Disorders; Movement Disorder | 1966 |