dimercaprol has been researched along with Experimental Radiation Injuries in 5 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| USPENSKAIA, MS | 1 |
| IZERGINA, AG | 1 |
| POLUBOIARINOVA, ZI | 1 |
| ARBUZOV, SI | 1 |
| Laconi, A | 1 |
| Buscemi, M | 1 |
| Cardinale, A | 1 |
| De Simone, GF | 1 |
| Pasqualino, A | 1 |
| Tessitore, V | 1 |
| Manoĭlov, SE | 1 |
| Grannikova, AV | 1 |
5 other studies available for dimercaprol and Experimental Radiation Injuries
| Article | Year |
|---|---|
[THE EFFECT OF UNITHIOL ON THE EXCRETION OF DISCHE-POSITIVE COMPOUNDS IN THE URINE OF RATS EXPOSED TO POLONIUM-210].
Topics: Animals; Body Fluids; Dimercaprol; Pharmacology; Polonium; Radiation Injuries; Radiation Injuries, E | 1963 |
[THE ACTION OF UNITHIOL ON RENAL FUNCTION IN DOGS SUBJECTED TO IONIZING RADIATIONS].
Topics: Animals; Dimercaprol; Dogs; Kidney Diseases; Pharmacology; Radiation Injuries; Radiation Injuries, E | 1963 |
[ROLE OF THE CENTRAL NERVOUS SYSTEM IN RESTORATIVE AND COMPENSATORY PROCESSES FOLLOWING THE ACTION OF RADIATION-PROTECTIVE AGENTS].
Topics: Animals; Central Nervous System; Central Nervous System Stimulants; Cerebral Cortex; Chlorpromazine; | 1963 |
[Protective effect of complexogenic drugs (BAL, alpha-mercaptopropionyl-glycine) on some enzyme activities of the kidney of rats treated with chlormerodrin-Hg197. Histochemical studies].
Topics: Acetylglucosaminidase; Adenosine Triphosphatases; Amino Acids, Sulfur; Animals; Chlormerodrin; Dimer | 1975 |
[The protective action of dicaptol in acute radiation sickness].
Topics: Animals; Dimercaprol; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats | 1966 |