dimercaprol has been researched along with Diseases of Immune System in 2 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (50.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
HASSELMANN, CM | 1 |
RICHTER, R | 1 |
BERGMANN, A | 1 |
EILLES, W | 1 |
JOHNE, HO | 1 |
Mas, M | 1 |
Cavaillès, P | 1 |
Colacios, C | 1 |
Subra, JF | 1 |
Lagrange, D | 1 |
Calise, M | 1 |
Christen, MO | 1 |
Druet, P | 1 |
Pelletier, L | 1 |
Gauguier, D | 1 |
Fournié, GJ | 1 |
2 other studies available for dimercaprol and Diseases of Immune System
Article | Year |
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[Experimental and clinical observations on necrosis of muscle following injection of BAL and sulfactin (Homburg), and its relation to the Sanarelli-Shwartzman phenomenon].
Topics: Dimercaprol; Humans; Hypersensitivity; Immune System Diseases; Muscles; Necrosis; Shwartzman Phenome | 1951 |
Studies of congenic lines in the Brown Norway rat model of Th2-mediated immunopathological disorders show that the aurothiopropanol sulfonate-induced immunological disorder (Aiid3) locus on chromosome 9 plays a major role compared to Aiid2 on chromosome 1
Topics: Animals; Animals, Congenic; Chromosome Mapping; Crosses, Genetic; Dimercaprol; Disease Models, Anima | 2004 |