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dimercaprol and Diabetic Neuropathies

dimercaprol has been researched along with Diabetic Neuropathies in 3 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SCHNEIDER, RW1
Efimov, AS2
Tkach, SN2

Other Studies

3 other studies available for dimercaprol and Diabetic Neuropathies

ArticleYear
The use of British anti-lewisite (BAL) in the treatment of diabetic neuropathy; clinical study; preliminary report.
    Cleveland Clinic quarterly, 1950, Volume: 17, Issue:4

    Topics: Biomedical Research; Diabetes Mellitus; Diabetic Neuropathies; Dimercaprol; Humans

1950
[Unithiol in the treatment of diabetic polyneuropathies].
    Sovetskaia meditsina, 1981, Issue:9

    Topics: Adult; Diabetic Neuropathies; Dimercaprol; Female; Humans; Male; Middle Aged; Neural Conduction; Pol

1981
[Normalization of sorbitol dehydrogenase activity--an important factor in the treatment of neuropathies and angiopathies in patients with diabetes mellitus].
    Vrachebnoe delo, 1986, Issue:6

    Topics: Adolescent; Adult; Diabetic Angiopathies; Diabetic Neuropathies; Dimercaprol; Enzyme Activation; Hum

1986