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dimercaprol and Dermatoses

dimercaprol has been researched along with Dermatoses in 9 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Research Excerpts

ExcerptRelevanceReference
"In the German Federal Republic it has recently become known that generalised disorders of chronic mercury poisoning (loss of weight, stomatitis, hearing and sensory loss, emotional disturbances) have accompanied the cardinal signs of nail discolouration and loss of hair."7.65[Nail changes and loss of hair: cardinal signs of mercury poisoning from hair bleaches (author's transl)]. ( Herpers, H; Käferstein, H; Orfanos, CE; Steinbach, H; Wüstner, H, 1975)
"The importance of arsenic poisoning by herbal preparations is discussed, as there are no known reports of their association."5.25Arsenic poisoning from anti-asthmatic herbal preparations. ( Seah, CS; Tay, CH, 1975)
"In the German Federal Republic it has recently become known that generalised disorders of chronic mercury poisoning (loss of weight, stomatitis, hearing and sensory loss, emotional disturbances) have accompanied the cardinal signs of nail discolouration and loss of hair."3.65[Nail changes and loss of hair: cardinal signs of mercury poisoning from hair bleaches (author's transl)]. ( Herpers, H; Käferstein, H; Orfanos, CE; Steinbach, H; Wüstner, H, 1975)
"Acute arsenic poisoning is less frequent and it is most often lethal."1.33[A case of neuropathy mimicking Guillain-Barré syndrome after arsenic intoxication]. ( Defebvre, L; Destee, A; Devos, D; Hurtevent, JF; Perriol, MP; Saulnier, F; Tiffreau, V, 2006)
"The importance of arsenic poisoning by herbal preparations is discussed, as there are no known reports of their association."1.25Arsenic poisoning from anti-asthmatic herbal preparations. ( Seah, CS; Tay, CH, 1975)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MULLER, M1
PAUL, KG1
THYRESSON, N1
PESSAGNO ESPORA, MA1
GHIRINGHELLI, L1
BARTALINI, E1
Perriol, MP1
Devos, D1
Hurtevent, JF1
Tiffreau, V1
Saulnier, F1
Destee, A1
Defebvre, L1
Tsyganok, SS1
Wüstner, H1
Orfanos, CE1
Steinbach, H1
Käferstein, H1
Herpers, H1
Tay, CH1
Seah, CS1
Witzgall, H1

Trials

1 trial available for dimercaprol and Dermatoses

ArticleYear
[Unithiol in the treatment of dermatoses].
    Vestnik dermatologii i venerologii, 1978, Issue:9

    Topics: Adolescent; Adult; Chronic Disease; Clinical Trials as Topic; Dimercaprol; Drug Evaluation; Eczema;

1978

Other Studies

8 other studies available for dimercaprol and Dermatoses

ArticleYear
[The practical value of dithioglycerin (BAL) in dermatology].
    Das Deutsche Gesundheitswesen, 1953, Jun-25, Volume: 8, Issue:26

    Topics: Dermatology; Dimercaprol; Metals; Skin Diseases

1953
The effect of BAL on a case of cutaneous porphyria.
    Acta dermato-venereologica, 1954, Volume: 34, Issue:5

    Topics: Administration, Cutaneous; Dimercaprol; Porphyrias; Skin Diseases

1954
[Current status of BAL therapy].
    El Dia medico, 1955, Aug-29, Volume: 27, Issue:61

    Topics: Dimercaprol; Heavy Metal Poisoning; Humans; Liver Diseases; Metals; Metals, Heavy; Poisoning; Skin D

1955
[Dermatosis caused by hypersensitivity to arsenic compounds: case report].
    La Medicina del lavoro, 1956, Volume: 47, Issue:4

    Topics: Arsenic Poisoning; Dermatitis; Dermatitis, Contact; Dimercaprol; Drug Eruptions; Humans; Skin Diseas

1956
[A case of neuropathy mimicking Guillain-Barré syndrome after arsenic intoxication].
    Revue neurologique, 2006, Volume: 162, Issue:3

    Topics: Acute Kidney Injury; Arsenic Poisoning; Chelating Agents; Chelation Therapy; Diagnosis, Differential

2006
[Nail changes and loss of hair: cardinal signs of mercury poisoning from hair bleaches (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1975, Aug-22, Volume: 100, Issue:34

    Topics: Alopecia; Chronic Disease; Cosmetics; Dimercaprol; Female; Humans; Mercury; Mercury Poisoning; Middl

1975
Arsenic poisoning from anti-asthmatic herbal preparations.
    The Medical journal of Australia, 1975, Sep-13, Volume: 2, Issue:11

    Topics: Adolescent; Adult; Arsenic; Arsenic Poisoning; Asthma; Child; Child, Preschool; Dimercaprol; Female;

1975
[Gold therapy in chronic joint rheumatism].
    Der Internist, 1967, Volume: 8, Issue:7

    Topics: Acute Kidney Injury; Arthritis, Rheumatoid; Dimercaprol; Drug Hypersensitivity; Gold; Hematologic Di

1967