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dimercaprol and Dermatitis

dimercaprol has been researched along with Dermatitis in 29 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Dermatitis: Any inflammation of the skin.

Research Excerpts

ExcerptRelevanceReference
"One hundred sixty-two consecutive patients with rheumatoid arthritis (RA) were studied for possible association between HLA antigens, particularly DR antigens, and disease characteristics and adverse reactions to gold or D-penicillamine treatment."3.67A systematic survey of HLA-A,B,C and D antigens and drug toxicity in rheumatoid arthritis. ( Dequeker, J; Van Wanghe, P; Verdickt, W, 1984)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199028 (96.55)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mouret, S1
Wartelle, J1
Emorine, S1
Bertoni, M1
Nguon, N1
Cléry-Barraud, C1
Dorandeu, F1
Boudry, I1
GRAY, JJ1
LAINE, VA1
GREEN, B1
RUSSELL, BF1
CARLETON, AB1
PETERS, RA1
THOMPSON, RH1
SIMPSON, NR1
EDSTROM, G3
BURNETT, JA1
SLOT, G1
McDONALD, AD1
LONGCOPE, WT1
LUETSCHER, JA1
BOAS, H2
COLE, HN1
KRESBACH, H2
SCHWARZBAUER, R1
BOHM, C1
SINGER, L1
GHIRINGHELLI, L1
BARTALINI, E1
KEILLER, FE1
WARIN, RP1
VOIGT, GE1
LANGHOF, H1
MUTING, D1
MØLLER, P1
ROOS, S1
CERESA, C1
KIRSCH, N1
HAGEMANN, PO1
BAGBY, JW1
RITTEY, DA1
MOSS, LF1
TOONE, EC1
Dequeker, J1
Van Wanghe, P1
Verdickt, W1

Other Studies

29 other studies available for dimercaprol and Dermatitis

ArticleYear
Topical efficacy of dimercapto-chelating agents against lewisite-induced skin lesions in SKH-1 hairless mice.
    Toxicology and applied pharmacology, 2013, Oct-15, Volume: 272, Issue:2

    Topics: Administration, Topical; Animals; Arsenic Poisoning; Arsenicals; Chelating Agents; Dermatitis; Dimer

2013
A case of arsenical dermatitis treated with BAL.
    Journal. Medical Association of Eire, 1948, Volume: 23, Issue:135

    Topics: Arsenic; Arsenic Poisoning; Dermatitis; Dimercaprol

1948
[Not Available].
    Duodecim; laaketieteellinen aikakauskirja, 1948, Volume: 64, Issue:3

    Topics: Dermatitis; Dimercaprol; Gold; Humans; Organogold Compounds; Poisoning

1948
Gold dermatitis, treated with B.A.L.; toxic manifestations; related (?) to calcium deprivation.
    Proceedings of the Royal Society of Medicine, 1948, Volume: 41, Issue:2

    Topics: Calcium, Dietary; Dermatitis; Dimercaprol; Gold

1948
The treatment of arsenical dermatitis with dimercaptopropanol (BAL).
    The Quarterly journal of medicine, 1948, Volume: 17, Issue:65

    Topics: Arsenicals; Dermatitis; Dimercaprol

1948
Treatment of gold dermatitis by BAL.
    British medical journal, 1948, Mar-20, Volume: 1, Issue:4550

    Topics: Dermatitis; Dimercaprol; Gold

1948
BAL therapy for gold dermatitis.
    Nordisk medicin, 1948, Jan-02, Volume: 37, Issue:1

    Topics: Dermatitis; Dimercaprol; Gold; Gold Compounds; Organogold Compounds

1948
BAL in the treatment of gold dermatitis.
    British medical journal, 1947, Oct-25, Volume: 2, Issue:4529

    Topics: Dermatitis; Dimercaprol; Gold; Humans

1947
The use and value of BAL in gold dermatitis.
    British medical journal, 1947, Nov-15, Volume: 2, Issue:4532

    Topics: Dermatitis; Dimercaprol; Gold; Humans

1947
Clinical uses of 2,3-dimercaptopropanol (BAL); the treatment of arsenical dermatitis with preparations of BAL.
    The Journal of clinical investigation, 1946, Volume: 25, Issue:4

    Topics: Arsenic; Arsenicals; Dermatitis; Dimercaprol

1946
[A case of gold dermatitis, unchanged by BAL, healed by sodium thiosulfate].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1952, Volume: 3, Issue:9

    Topics: Cold Temperature; Dermatitis; Dimercaprol; Drug Eruptions; Gold; Humans; Thiosulfates

1952
Use of dimercaprol (BAL) ointment in chronic chrome dermatitis.
    A.M.A. archives of dermatology and syphilology, 1953, Volume: 67, Issue:1

    Topics: Chromium; Chromium Radioisotopes; Chronic Disease; Dermatitis; Dermatitis, Contact; Dimercaprol; Hum

1953
[Severe DDT dermatitis with considerable disturbance of general health and symptoms in internal organs; cure with BAL].
    Wiener klinische Wochenschrift, 1953, Jul-03, Volume: 65, Issue:27

    Topics: DDT; Dermatitis; Dermatitis, Contact; Dimercaprol

1953
[Experimental studies on the therapeutic effects of BAL in a severe contact dermatitis caused by DDT].
    Klinische Medizin; osterreichische Zeitschrift fur wissenschaftliche und praktische Medizin, 1953, Oct-01, Volume: 8, Issue:10

    Topics: DDT; Dermatitis; Dermatitis, Contact; Dimercaprol

1953
[Complications and one fatality, in exsudative spirotrypan dermatitis treated with sulfactin].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1954, Volume: 5, Issue:7

    Topics: Arsenicals; Arsphenamine; Bone Diseases; Dermatitis; Dimercaprol; Disease; Drug Eruptions; Muscles;

1954
[Dermatosis caused by hypersensitivity to arsenic compounds: case report].
    La Medicina del lavoro, 1956, Volume: 47, Issue:4

    Topics: Arsenic Poisoning; Dermatitis; Dermatitis, Contact; Dimercaprol; Drug Eruptions; Humans; Skin Diseas

1956
Mercury dermatitis in a tattoo: treated with dimercaprol.
    British medical journal, 1957, Mar-23, Volume: 1, Issue:5020

    Topics: Dermatitis; Dimercaprol; Humans; Mercury; Tattooing

1957
[Histochemical studies on gold in gold dermatitis before and after BAL treatment].
    Acta rheumatologica Scandinavica, 1959, Volume: 5

    Topics: Dermatitis; Dermatitis, Contact; Dimercaprol; Gold

1959
[Amino acid balance and BAL therapy of photodermatitis].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1955, Volume: 6, Issue:1

    Topics: Amino Acids; Dermatitis; Dimercaprol; Photosensitivity Disorders

1955
Treatment of a patient for sanocrysin dermatitis with BAL.
    Acta dermato-venereologica, 1950, Volume: 30, Issue:4

    Topics: Dermatitis; Dimercaprol; Drug Eruptions; Gold; Humans; Organogold Compounds

1950
Case of arsphenamine dermatitis treated with BAL.
    Acta dermato-venereologica, 1950, Volume: 30, Issue:5

    Topics: Arsphenamine; Dermatitis; Dimercaprol; Drug Eruptions

1950
[Occupational manganese poisoning treated with 2-3 mercaptopropanol].
    La Medicina del lavoro, 1951, Volume: 42, Issue:1

    Topics: Dermatitis; Dimercaprol; Humans; Manganese; Manganese Poisoning

1951
Acute gold dermatitis successfully treated with BAL.
    Connecticut state medical journal, 1951, Volume: 15, Issue:3

    Topics: Dermatitis; Dimercaprol; Gold; Humans; Organogold Compounds

1951
[A case of gold dermatitis with negative BAL therapy, improved by sodium thiosulfate].
    Ugeskrift for laeger, 1952, Jun-12, Volume: 114, Issue:24

    Topics: Dermatitis; Dimercaprol; Drug Eruptions; Gold; Humans; Thiosulfates

1952
Dermatitis due to BAL (2,3-dithiopropanol) a complication in the treatment of gold dermatitis.
    Missouri medicine, 1949, Volume: 46, Issue:11

    Topics: Dermatitis; Dimercaprol; Gold

1949
Dimercaprol in acute antimony dermatitis.
    Lancet (London, England), 1950, Feb-11, Volume: 1, Issue:6598

    Topics: Acute Disease; Antimony; Dermatitis; Dimercaprol; Humans

1950
The successful treatment of gold dermatitis with British antilewisite; a case report.
    Virginia medical monthly, 1949, Volume: 76, Issue:1

    Topics: Antidotes; Dermatitis; Dermatitis, Allergic Contact; Dimercaprol; Gold; Gold Compounds; Humans; Orga

1949
Bal-therapy for gold dermatitis.
    Nordisk medicin, 1949, Jan-14, Volume: 41, Issue:2

    Topics: Dermatitis; Dimercaprol; Gold; Gold Compounds; Organogold Compounds

1949
A systematic survey of HLA-A,B,C and D antigens and drug toxicity in rheumatoid arthritis.
    The Journal of rheumatology, 1984, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Cytotoxicity Tests, Immunologic; Dermatitis; Dimerca

1984