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dimercaprol and Dermatitis Medicamentosa

dimercaprol has been researched along with Dermatitis Medicamentosa in 11 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Research Excerpts

ExcerptRelevanceReference
"Fifty patients with a significant rheumatoid arthritis (RA) were treated with gold salts for 6 months to 4 years."5.05[Comparative analysis of the effectiveness and tolerance of chrysanol and myochrysine in patients with rheumatoid arthritis (preliminary report)]. ( Slobodina, GA, 1985)
"Although treatment has been well defined for childhood lead poisoning and for industrial lead exposure, the treatment of lead nephropathy has been poorly studied."3.65Chelation therapy in lead nephropathy. ( Morgan, JM, 1975)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199011 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BOAS, H2
DAUER, HJ1
BOHM, C1
SINGER, L1
GHIRINGHELLI, L1
BARTALINI, E1
MØLLER, P1
ROOS, S1
Morgan, JM1
Philips, VK1
Slobodina, GA1
Kalamkarian, AA1
Somov, BA1
Fedorov, SM1
Persina, IS1

Reviews

1 review available for dimercaprol and Dermatitis Medicamentosa

ArticleYear
Intramuscular gold for rheumatoid arthritis.
    Comprehensive therapy, 1977, Volume: 3, Issue:6

    Topics: Arthritis, Rheumatoid; Dimercaprol; Drug Administration Schedule; Drug Eruptions; Female; Gold; Huma

1977

Trials

1 trial available for dimercaprol and Dermatitis Medicamentosa

ArticleYear
[Comparative analysis of the effectiveness and tolerance of chrysanol and myochrysine in patients with rheumatoid arthritis (preliminary report)].
    Terapevticheskii arkhiv, 1985, Volume: 57, Issue:7

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Clinical Trials as Topic; Dimercaprol; Drug E

1985

Other Studies

9 other studies available for dimercaprol and Dermatitis Medicamentosa

ArticleYear
[A case of gold dermatitis, unchanged by BAL, healed by sodium thiosulfate].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1952, Volume: 3, Issue:9

    Topics: Cold Temperature; Dermatitis; Dimercaprol; Drug Eruptions; Gold; Humans; Thiosulfates

1952
[An unusually severe allergic dermatitis after use of BAL (sulfactin)].
    Dermatologische Wochenschrift, 1953, Volume: 127, Issue:6

    Topics: Dimercaprol; Drug Eruptions

1953
[Complications and one fatality, in exsudative spirotrypan dermatitis treated with sulfactin].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1954, Volume: 5, Issue:7

    Topics: Arsenicals; Arsphenamine; Bone Diseases; Dermatitis; Dimercaprol; Disease; Drug Eruptions; Muscles;

1954
[Dermatosis caused by hypersensitivity to arsenic compounds: case report].
    La Medicina del lavoro, 1956, Volume: 47, Issue:4

    Topics: Arsenic Poisoning; Dermatitis; Dermatitis, Contact; Dimercaprol; Drug Eruptions; Humans; Skin Diseas

1956
Treatment of a patient for sanocrysin dermatitis with BAL.
    Acta dermato-venereologica, 1950, Volume: 30, Issue:4

    Topics: Dermatitis; Dimercaprol; Drug Eruptions; Gold; Humans; Organogold Compounds

1950
Case of arsphenamine dermatitis treated with BAL.
    Acta dermato-venereologica, 1950, Volume: 30, Issue:5

    Topics: Arsphenamine; Dermatitis; Dimercaprol; Drug Eruptions

1950
[A case of gold dermatitis with negative BAL therapy, improved by sodium thiosulfate].
    Ugeskrift for laeger, 1952, Jun-12, Volume: 114, Issue:24

    Topics: Dermatitis; Dimercaprol; Drug Eruptions; Gold; Humans; Thiosulfates

1952
Chelation therapy in lead nephropathy.
    Southern medical journal, 1975, Volume: 68, Issue:8

    Topics: Acute Kidney Injury; Administration, Oral; Chelating Agents; Creatinine; Dimercaprol; Drug Eruptions

1975
[Gold-induced dermatitis (contact dermatitis and toxiderma)].
    Vestnik dermatologii i venerologii, 1985, Issue:8

    Topics: Adult; Dermatitis, Contact; Dermatitis, Occupational; Dimercaprol; Drug Eruptions; Female; Gold; Hum

1985