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dimercaprol and Delirium

dimercaprol has been researched along with Delirium in 4 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Delirium: A disorder characterized by CONFUSION; inattentiveness; disorientation; ILLUSIONS; HALLUCINATIONS; agitation; and in some instances autonomic nervous system overactivity. It may result from toxic/metabolic conditions or structural brain lesions. (From Adams et al., Principles of Neurology, 6th ed, pp411-2)

Research Excerpts

ExcerptRelevanceReference
"A 50-year-old chemical engineer, routinely screened for occupational arsenic exposure, was admitted with a delirium for which no known etiology was found."3.67Neuropsychological impairment following inorganic arsenic exposure. ( Bleecker, ML; Bolla-Wilson, K, 1987)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ABDEL-GHAFFAR, Y1
SHERIF, YA1
EL-MASSRY, ZH1
BARSOOM, KA1
Mattle, H1
Henn, V1
Baumgartner, G1
Dubowitz, MN1
Hughes, PJ1
Lane, RJ1
Wade, JP1
Bolla-Wilson, K1
Bleecker, ML1

Other Studies

4 other studies available for dimercaprol and Delirium

ArticleYear
LEAD ENCEPHALOPATHY: CASE REPORT.
    The Journal of the Egyptian Medical Association, 1963, Volume: 46

    Topics: Blood Chemical Analysis; Coma; Delirium; Dimercaprol; Lead Poisoning; Neurologic Examination; Neurot

1963
[Acute delirium in bismuth poisoning].
    Schweizerische medizinische Wochenschrift, 1982, Sep-18, Volume: 112, Issue:38

    Topics: Bismuth; Chelating Agents; Delirium; Dexamethasone; Diagnosis, Differential; Dimercaprol; Drug Thera

1982
Gold-induced neuroencephalopathy responding to dimercaprol.
    Lancet (London, England), 1991, Apr-06, Volume: 337, Issue:8745

    Topics: Arthritis, Rheumatoid; Delirium; Dimercaprol; Drug Administration Schedule; Gold Sodium Thiomalate;

1991
Neuropsychological impairment following inorganic arsenic exposure.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1987, Volume: 29, Issue:6

    Topics: Arsenic; Auditory Perceptual Disorders; Cognition Disorders; Consciousness Disorders; Delirium; Dime

1987