Page last updated: 2024-10-26

dimercaprol and Complications, Pregnancy

dimercaprol has been researched along with Complications, Pregnancy in 5 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Research Excerpts

ExcerptRelevanceReference
" The mother was prescribed a single course of oral succimer late in the third trimester of pregnancy, without any appreciable change in her blood lead."3.71Lead poisoning and chelation in a mother-neonate pair. ( Horowitz, BZ; Mirkin, DB, 2001)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mycyk, MB1
Leikin, JB1
Horowitz, BZ1
Mirkin, DB1
Pierce, PE1
Thompson, JF1
Likosky, WH1
Nickey, LN1
Barthel, WF1
Hinman, AR1
Lugo, G1
Cassady, G1
Palmisano, P1
Dreifuss, FE1
McKinney, WM1

Other Studies

5 other studies available for dimercaprol and Complications, Pregnancy

ArticleYear
Combined exchange transfusion and chelation therapy for neonatal lead poisoning.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:5

    Topics: Adult; Ceramics; Chelating Agents; Chelation Therapy; Combined Modality Therapy; Dimercaprol; Edetic

2004
Lead poisoning and chelation in a mother-neonate pair.
    Journal of toxicology. Clinical toxicology, 2001, Volume: 39, Issue:7

    Topics: Adult; Chelating Agents; Chelation Therapy; Dimercaprol; Edetic Acid; Female; Fetal Blood; Humans; I

2001
Alkyl mercury poisoning in humans. Report of an outbreak.
    JAMA, 1972, Jun-12, Volume: 220, Issue:11

    Topics: Adolescent; Adult; Amniocentesis; Animal Feed; Ataxia; Cerebellum; Child; Child, Preschool; Coma; Di

1972
Acute maternal arsenic intoxication with neonatal death.
    American journal of diseases of children (1960), 1969, Volume: 117, Issue:3

    Topics: Acute Kidney Injury; Adolescent; Arsenic; Arsenic Poisoning; Brain; Dimercaprol; Female; Humans; Hya

1969
Wilson's disease (hepatolenticular degeneration) and pregnancy.
    JAMA, 1966, Mar-14, Volume: 195, Issue:11

    Topics: Adult; Ceruloplasmin; Dimercaprol; Female; Hepatolenticular Degeneration; Humans; Pregnancy; Pregnan

1966