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dimercaprol and Chemical Dependence

dimercaprol has been researched along with Chemical Dependence in 5 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Research Excerpts

ExcerptRelevanceReference
"These data suggest that neurological manifestations occur frequently in those abusing leaded gasoline and that chelation therapy has an important place in their management."1.26The neurological manifestations of chronic inhalation of leaded gasoline. ( Boeckx, RL; Chow, PN; Rjani, KR; Seshia, SS, 1978)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kurt, TL1
McAnalley, BH1
Garriott, JC1
Mattle, H1
Henn, V1
Baumgartner, G1
Burns, CB1
Currie, B1
Seshia, SS1
Rjani, KR1
Boeckx, RL1
Chow, PN1
Edminster, SC1
Bayer, MJ1

Other Studies

5 other studies available for dimercaprol and Chemical Dependence

ArticleYear
Lead encephalopathy from gasoline sniffing: successful treatment with chelation.
    Texas medicine, 1982, Volume: 78, Issue:9

    Topics: Adolescent; Brain Diseases; Chelating Agents; Dexamethasone; Dimercaprol; Edetic Acid; Gasoline; Hum

1982
[Acute delirium in bismuth poisoning].
    Schweizerische medizinische Wochenschrift, 1982, Sep-18, Volume: 112, Issue:38

    Topics: Bismuth; Chelating Agents; Delirium; Dexamethasone; Diagnosis, Differential; Dimercaprol; Drug Thera

1982
The efficacy of chelation therapy and factors influencing mortality in lead intoxicated petrol sniffers.
    Australian and New Zealand journal of medicine, 1995, Volume: 25, Issue:3

    Topics: Chelating Agents; Chelation Therapy; Dimercaprol; Edetic Acid; Gasoline; Humans; Lead; Lead Poisonin

1995
The neurological manifestations of chronic inhalation of leaded gasoline.
    Developmental medicine and child neurology, 1978, Volume: 20, Issue:3

    Topics: Adolescent; Adult; Child; Child, Preschool; Dimercaprol; Edetic Acid; Electrocardiography; Electroen

1978
Recreational gasoline sniffing: acute gasoline intoxication and latent organolead poisoning. Case reports and literature review.
    The Journal of emergency medicine, 1985, Volume: 3, Issue:5

    Topics: Adolescent; Adult; Dimercaprol; Edetic Acid; Gasoline; Humans; Male; Organometallic Compounds; Petro

1985