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dimercaprol and Central Nervous System Disease

dimercaprol has been researched along with Central Nervous System Disease in 5 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
SALZER, HM1
RAVIN, HA1
Scena, MR1
Vroom, FQ1
Greer, M1
Schergna, E1

Other Studies

5 other studies available for dimercaprol and Central Nervous System Disease

ArticleYear
BAL in the treatment of neurological syndromes.
    Diseases of the nervous system, 1954, Volume: 15, Issue:3

    Topics: Central Nervous System Diseases; Databases, Genetic; Dimercaprol; Syndrome

1954
WILSON'S DISEASE, AN INBORN ERROR OF METABOLISM AND A MODEL OF DEGENERATIVE CENTRAL NERVOUS SYSTEM DISEASE.
    Bulletin - Sinai Hospital of Detroit, 1964, Volume: 12

    Topics: Central Nervous System Diseases; Chelating Agents; Copper; Dimercaprol; Hepatolenticular Degeneratio

1964
Melarsoprol toxicity in the treatment of human African trypanosomiasis. Ten cases treated with dimercaprol.
    The Central African journal of medicine, 1988, Volume: 34, Issue:11

    Topics: Adolescent; Adult; Arsenicals; Central Nervous System Diseases; Dimercaprol; Female; Humans; Male; M

1988
Mercury vapour intoxication.
    Brain : a journal of neurology, 1972, Volume: 95, Issue:2

    Topics: Action Potentials; Adult; Aged; Bender-Gestalt Test; Central Nervous System Diseases; Dimercaprol; E

1972
[Recent therapeutic conquests in extrapyramidal syndromes].
    Minerva medica, 1970, Dec-19, Volume: 61, Issue:101

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Amantadine; Athetosis; Brain Diseases; Central

1970