dimercaprol and Autoimmune Disease
dimercaprol has been researched along with Autoimmune Disease in 4 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Field, AC | 1 |
| Bloch, MF | 1 |
| Bellon, B | 1 |
| Tournade, H | 3 |
| Guery, JC | 3 |
| Pasquier, R | 2 |
| Vial, MC | 1 |
| Mandet, C | 1 |
| Druet, E | 2 |
| Dansette, PM | 1 |
| Druet, P | 3 |
| Pelletier, L | 3 |
| Nochy, D | 1 |
| Hinglais, N | 1 |
| Guilbert, B | 1 |
Other Studies
4 other studies available for dimercaprol and Autoimmune Disease
| Article | Year |
|---|---|
Neonatal tolerance to a Th2-mediated autoimmune disease generates CD8+ Tc1 regulatory cells.
Topics: Adoptive Transfer; Animals; Animals, Newborn; Apoptosis; Autoimmune Diseases; CD4 Antigens; CD4-Posi | 2003 |
Effect of the thiol group on experimental gold-induced autoimmunity.
Topics: Animals; Antirheumatic Agents; Autoimmune Diseases; Autoimmunity; Dimercaprol; Disease Models, Anima | 1991 |
Experimental gold-induced autoimmunity.
Topics: Animals; Autoantibodies; Autoimmune Diseases; Autoimmunity; Dimercaprol; Female; Glomerulonephritis, | 1991 |
Rat anti-glomerular basement membrane antibodies in toxin-induced autoimmunity and in chronic graft-vs.-host reaction share recurrent idiotypes.
Topics: Animals; Autoantibodies; Autoimmune Diseases; Basement Membrane; Cross Reactions; Dimercaprol; Fluor | 1990 |