Page last updated: 2024-10-26

dimercaprol and Atherosclerotic Parkinsonism

dimercaprol has been researched along with Atherosclerotic Parkinsonism in 2 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Research Excerpts

ExcerptRelevanceReference
"DP reduced acrolein and reversed the upregulation of pain-sensing transient receptor potential ankyrin 1 (TRPA1) channels in the substantia nigra, striatum, and cortex."4.02Acrolein scavenger dimercaprol offers neuroprotection in an animal model of Parkinson's disease: implication of acrolein and TRPA1. ( Chen, Z; Herr, SA; Jiao, Y; Lin, Y; Rogers, E; Shi, L; Shi, R; Tang, J, 2021)
"Two cases of myoclonic encephalopathy due to bismuth salts intoxication are reported."1.28Myoclonic encephalopathy due to bismuth salts: treatment with dimercaprol and analysis of CSF transmitters. ( Bermejo, F; Calandre, L; Molina, JA, 1989)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Shi, L1
Lin, Y1
Jiao, Y1
Herr, SA1
Tang, J1
Rogers, E1
Chen, Z1
Shi, R1
Molina, JA1
Calandre, L1
Bermejo, F1

Other Studies

2 other studies available for dimercaprol and Atherosclerotic Parkinsonism

ArticleYear
Acrolein scavenger dimercaprol offers neuroprotection in an animal model of Parkinson's disease: implication of acrolein and TRPA1.
    Translational neurodegeneration, 2021, 04-28, Volume: 10, Issue:1

    Topics: Acrolein; Animals; Behavior, Animal; Cerebral Cortex; Dimercaprol; Dopaminergic Neurons; Hydroxydopa

2021
Myoclonic encephalopathy due to bismuth salts: treatment with dimercaprol and analysis of CSF transmitters.
    Acta neurologica Scandinavica, 1989, Volume: 79, Issue:3

    Topics: Adult; Aged; Dimercaprol; Epilepsies, Myoclonic; Female; Gallic Acid; Humans; Male; Neurotransmitter

1989