dimercaprol has been researched along with Arsenic Encephalopathy in 117 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In massive arsenic poisoning, the use of hemodialysis and dimercaprol (BAL) therapy is still controversial." | 7.68 | Massive arsenic poisoning--effect of hemodialysis and dimercaprol on arsenic kinetics. ( Furon, D; Germain-Alonso, M; Mathieu, D; Mathieu-Nolf, M; Neviere, R; Wattel, F, 1992) |
| "An acute massive epidemic of arsenic poisoning in Argentina involved 718 subjects." | 7.68 | Mass poisoning by sodium arsenite. ( Camussa, N; García Fernández, JC; Martínez de Marco, M; Minetti, SA; Quiroga, PN; Rattay, P; Roses, OE; Sassone, A; Valle, G; Villaamil, EC, 1991) |
| "The importance of arsenic poisoning by herbal preparations is discussed, as there are no known reports of their association." | 5.25 | Arsenic poisoning from anti-asthmatic herbal preparations. ( Seah, CS; Tay, CH, 1975) |
| "1 Dimercaprol (BAL), 2,3-dimercaptopropanesulphonate sodium (DMPS) and meso-2,3-dimercaptosuccinic acid (DMSA) are effective arsenic antidotes, but the question which one is preferable for optimal therapy of arsenic poisoning is still open to discussion." | 4.79 | Are we ready to replace dimercaprol (BAL) as an arsenic antidote? ( Fichtl, B; Hunder, G; Liebl, B; Mückter, H; Reichl, FX; Walther, U, 1997) |
| "In massive arsenic poisoning, the use of hemodialysis and dimercaprol (BAL) therapy is still controversial." | 3.68 | Massive arsenic poisoning--effect of hemodialysis and dimercaprol on arsenic kinetics. ( Furon, D; Germain-Alonso, M; Mathieu, D; Mathieu-Nolf, M; Neviere, R; Wattel, F, 1992) |
| "An acute massive epidemic of arsenic poisoning in Argentina involved 718 subjects." | 3.68 | Mass poisoning by sodium arsenite. ( Camussa, N; García Fernández, JC; Martínez de Marco, M; Minetti, SA; Quiroga, PN; Rattay, P; Roses, OE; Sassone, A; Valle, G; Villaamil, EC, 1991) |
| "This report describes a case of acute arsenic poisoning, missed initially due to its gastroenteritis-like presentation, but suspected and confirmed much later, when the patient sought medical help for delayed complications after about 2 months." | 1.43 | Acute arsenic poisoning diagnosed late. ( Amin, MR; Anam, AM; Chowdhury, MA; Kamruzzaman, AK; Shumy, F, 2016) |
| "Acute arsenic poisoning is less frequent and it is most often lethal." | 1.33 | [A case of neuropathy mimicking Guillain-Barré syndrome after arsenic intoxication]. ( Defebvre, L; Destee, A; Devos, D; Hurtevent, JF; Perriol, MP; Saulnier, F; Tiffreau, V, 2006) |
| " The low toxicity of DMPS and DMSA compared to BAL enabled doses of 160 mumol kg-1 on a more prolonged dosing schedule to be used for DMPS and DMSA." | 1.29 | Efficacy of dimercapto chelating agents for the treatment of poisoning by percutaneously applied dichloro(2-chlorovinyl)arsine in rabbits. ( Inns, RH; Rice, P, 1993) |
| "We report three cases of arsenic poisoning in a chemical factory." | 1.29 | [Acute arsenic poisoning]. ( Abildtrup, A; Ebbehøj, NE; Eshøj, O; Johansen, JB; Kristensen, SR, 1996) |
| " Equimolar dosing schedules were used based upon realistic doses for the most toxic agent, BAL." | 1.28 | Evaluation of the efficacy of dimercapto chelating agents for the treatment of systemic organic arsenic poisoning in rabbits. ( Bright, JE; Inns, RH; Marrs, TC; Rice, P, 1990) |
| "It was concluded that the use of DPA in arsenic poisoning needs to be reevaluated." | 1.28 | Lack of effectiveness of D-penicillamine in experimental arsenic poisoning. ( Fichtl, B; Forth, W; Kreppel, H; Reichl, FX, 1989) |
| "Dimercaprol was among the first therapeutically useful metal chelating agents and was developed originally as an anti-lewisite agent." | 1.26 | Anti-lewisite activity and stability of meso-dimercaptosuccinic acid and 2,3-dimercapto-1-propanesulfonic acid. ( Aposhian, HV; Brinkley, FB; Hackley, BE; Hsu, CA; Mershon, MM, 1982) |
| "Treatment with dimercaprol remains the mainstay of therapy, and early treatment is necessary to prevent irreversible complications." | 1.26 | Arsenic poisoning. ( Schoolmeester, WL; White, DR, 1980) |
| "The use of D-penicillamine in arsenic poisoning has not been generally appreciated." | 1.26 | D-penicillamine therapy of acute arsenic poisoning. ( Peterson, RG; Rumack, BH, 1977) |
| "The importance of arsenic poisoning by herbal preparations is discussed, as there are no known reports of their association." | 1.25 | Arsenic poisoning from anti-asthmatic herbal preparations. ( Seah, CS; Tay, CH, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 88 (75.21) | 18.7374 |
| 1990's | 14 (11.97) | 18.2507 |
| 2000's | 7 (5.98) | 29.6817 |
| 2010's | 7 (5.98) | 24.3611 |
| 2020's | 1 (0.85) | 2.80 |
| Authors | Studies |
|---|---|
| Hsiao, CY | 1 |
| Gresham, C | 1 |
| Marshall, MR | 1 |
| Nurchi, VM | 1 |
| Djordjevic, AB | 1 |
| Crisponi, G | 1 |
| Alexander, J | 1 |
| Bjørklund, G | 1 |
| Aaseth, J | 2 |
| Hu, J | 1 |
| Wang, KY | 1 |
| Wang, T | 1 |
| Fernández Fernández, N | 1 |
| Estevez Boullosa, P | 1 |
| Gómez Rodríguez, A | 1 |
| Rodríguez Prada, JI | 1 |
| Mouret, S | 1 |
| Wartelle, J | 1 |
| Emorine, S | 1 |
| Bertoni, M | 1 |
| Nguon, N | 1 |
| Cléry-Barraud, C | 1 |
| Dorandeu, F | 1 |
| Boudry, I | 1 |
| Shumy, F | 1 |
| Anam, AM | 1 |
| Kamruzzaman, AK | 1 |
| Amin, MR | 1 |
| Chowdhury, MA | 1 |
| Li, C | 1 |
| Srivastava, RK | 1 |
| Athar, M | 1 |
| DE CORDOVA CASTRO, A | 1 |
| PENALVER BALLINA, R | 1 |
| GRAY, JJ | 1 |
| CHOTKOWSKI, LA | 1 |
| ARMSTRONG, CD | 1 |
| FLEMING, WJ | 1 |
| THALMANN, WG | 1 |
| MASTERS, JB | 1 |
| FRIEDENBERG, S | 1 |
| WOODY, NC | 1 |
| KOMETANI, JT | 1 |
| PROSSER-THOMAS, EW | 1 |
| SRIVASTAVA, SC | 1 |
| FERRARI, AV | 1 |
| Yilmaz, Y | 1 |
| Armagan, E | 1 |
| Olmez, O | 1 |
| Esen, M | 1 |
| Alkis, N | 1 |
| Dolar, E | 1 |
| STOCKEN, LA | 2 |
| THOMPSON, RH | 2 |
| COHEN, A | 1 |
| GOLDMAN, J | 1 |
| DUBBS, AW | 1 |
| WHITTAKER, VP | 1 |
| EAGLE, H | 4 |
| MAGNUSON, HJ | 2 |
| FLEISCHMAN, R | 2 |
| HUGHES, WF | 1 |
| LUETSCHER, JA | 1 |
| LONG-COPE, WT | 1 |
| Cox, RD | 1 |
| Orledge, J | 1 |
| WADE, HJ | 1 |
| FRAZER, ES | 1 |
| CORDERO, AA | 1 |
| MOSIG, A | 1 |
| SARTORELLI, E | 1 |
| FORNEY, RB | 1 |
| DAS GUPTA, A | 1 |
| PRASAD, B | 1 |
| HEYMAN, A | 1 |
| PFEIFFER, JB | 1 |
| WILLETT, RW | 1 |
| TAYLOR, HM | 1 |
| GHIRINGHELLI, L | 1 |
| BARTALINI, E | 1 |
| KEPLINGER, ML | 1 |
| TEBROCK, HE | 1 |
| DEICHMANN, WB | 1 |
| LASCH, F | 1 |
| SCHNEIBERG, K | 1 |
| IZAR, G | 1 |
| DELGA, J | 2 |
| GRIFFON, H | 1 |
| CLEMENT, Y | 1 |
| LEGAULT-DEMARE, J | 1 |
| ZINNY, M | 1 |
| BERLANGA, R | 1 |
| MENDIZABAL, J | 1 |
| MALHOTRA, SL | 1 |
| MARTINEZ PRADO, G | 1 |
| COMEZ DEL VALLE, C | 1 |
| PETERS, RA | 3 |
| MONTERO, R | 1 |
| BEATO, J | 1 |
| Namera, A | 1 |
| Yashiki, M | 1 |
| Aposhian, HV | 7 |
| Aposhian, MM | 1 |
| Perriol, MP | 1 |
| Devos, D | 1 |
| Hurtevent, JF | 1 |
| Tiffreau, V | 1 |
| Saulnier, F | 1 |
| Destee, A | 1 |
| Defebvre, L | 1 |
| Wang, EE | 1 |
| Mahajan, N | 1 |
| Wills, B | 1 |
| Leikin, J | 1 |
| Magdalan, J | 1 |
| Smolarek, M | 1 |
| Porebska, B | 1 |
| Zawadzki, M | 1 |
| Dyś, P | 1 |
| Flora, SJ | 1 |
| Bhadauria, S | 1 |
| Kannan, GM | 1 |
| Singh, N | 1 |
| BERMUDEZ ABREU, VP | 1 |
| LUSKY, LM | 1 |
| BRAUN, HA | 1 |
| LAUG, EP | 1 |
| Dawson, MA | 1 |
| Chhuttani, PN | 1 |
| Chawla, LS | 1 |
| Sharma, TD | 1 |
| Trinus, FP | 1 |
| Braber-Chernobul'skaia, BS | 1 |
| Chubenko, AV | 1 |
| Luĭk, AI | 1 |
| Grigor'eva, AS | 1 |
| Tadlock, CH | 1 |
| Mershon, MM | 1 |
| Brinkley, FB | 1 |
| Hsu, CA | 3 |
| Hackley, BE | 1 |
| Carter, DE | 1 |
| Hoover, TD | 1 |
| Maiorino, RM | 1 |
| Stine, E | 1 |
| Maehashi, H | 2 |
| Yamaguchi, Y | 1 |
| Tsutsumi, S | 1 |
| Heydolph, S | 1 |
| Parr, W | 1 |
| Christensen, P | 1 |
| Frost, JW | 1 |
| Søjbjerg, JO | 1 |
| Shum, S | 1 |
| Skarbovig, J | 1 |
| Habersang, R | 1 |
| Mahieu, P | 1 |
| Buchet, JP | 1 |
| Roels, HA | 1 |
| Lauwerys, R | 1 |
| Schoolmeester, WL | 1 |
| White, DR | 1 |
| Reichl, FX | 3 |
| Kreppel, H | 2 |
| Szinicz, L | 2 |
| Mückter, H | 4 |
| Fichtl, B | 5 |
| Forth, W | 4 |
| Liebl, B | 2 |
| Doklea, E | 2 |
| Inns, RH | 2 |
| Rice, P | 2 |
| Islambouli, S | 1 |
| Hopfer, C | 1 |
| Johansen, JB | 1 |
| Abildtrup, A | 1 |
| Ebbehøj, NE | 1 |
| Kristensen, SR | 1 |
| Eshøj, O | 1 |
| Hunder, G | 1 |
| Walther, U | 1 |
| Kamijo, Y | 1 |
| Soma, K | 1 |
| Asari, Y | 1 |
| Ohwada, T | 1 |
| Garb, LG | 1 |
| Hine, CH | 1 |
| Graziano, JH | 1 |
| Cuccia, D | 1 |
| Friedheim, E | 1 |
| Greenberg, C | 1 |
| Davies, S | 1 |
| McGowan, T | 1 |
| Schorer, A | 1 |
| Drage, C | 1 |
| Fernando, PR | 1 |
| Feldman, RG | 1 |
| Baker, EL | 1 |
| Dittrich, C | 1 |
| Panzer, S | 1 |
| Lomoschitz, KH | 1 |
| Vycudilik, W | 1 |
| Peterson, RG | 1 |
| Rumack, BH | 1 |
| Balatskiĭ, KP | 1 |
| Tay, CH | 1 |
| Seah, CS | 1 |
| Fleay, RF | 1 |
| Thomas, BW | 1 |
| Kosnett, MJ | 1 |
| Mathieu, D | 1 |
| Mathieu-Nolf, M | 1 |
| Germain-Alonso, M | 1 |
| Neviere, R | 1 |
| Furon, D | 1 |
| Wattel, F | 1 |
| Hilmy, AM | 1 |
| el-Domiaty, NA | 1 |
| Kamal, MA | 1 |
| Mohamed, MA | 1 |
| Abou Samra, WE | 1 |
| Jolliffe, DM | 1 |
| Budd, AJ | 1 |
| Gwilt, DJ | 1 |
| Roses, OE | 1 |
| García Fernández, JC | 1 |
| Villaamil, EC | 1 |
| Camussa, N | 1 |
| Minetti, SA | 1 |
| Martínez de Marco, M | 1 |
| Quiroga, PN | 1 |
| Rattay, P | 1 |
| Sassone, A | 1 |
| Valle, G | 1 |
| Goebel, HH | 1 |
| Schmidt, PF | 1 |
| Bohl, J | 1 |
| Tettenborn, B | 1 |
| Krämer, G | 1 |
| Gutmann, L | 1 |
| Bright, JE | 1 |
| Marrs, TC | 1 |
| Tallis, GA | 1 |
| Hall, JC | 1 |
| Harruff, R | 1 |
| Murata, Y | 1 |
| Fesmire, FM | 1 |
| Schauben, JL | 1 |
| Roberge, RJ | 1 |
| Kersjes, MP | 1 |
| Maurer, JR | 1 |
| Trestrail, JH | 1 |
| McCoy, DJ | 1 |
| Huang, YZ | 1 |
| Qian, XC | 1 |
| Wang, GQ | 1 |
| Xiao, BY | 1 |
| Ren, DD | 1 |
| Feng, ZY | 1 |
| Wu, JY | 1 |
| Xu, RJ | 1 |
| Zhang, FE | 1 |
| Miziukova, IG | 1 |
| Petrun'kin, VE | 1 |
| Oehme, FW | 1 |
| Zavon, MR | 1 |
| Gitter, E | 1 |
| Bonitz, G | 1 |
| Schütz, W | 1 |
| Pétenyi, M | 1 |
| Wolf, R | 1 |
| Chisolm, JJ | 1 |
| St Petery, J | 1 |
| Rennert, OM | 1 |
| Choi, H | 1 |
| Wolfson, S | 1 |
| Kobayashi, A | 1 |
| Obe, Y | 1 |
| Lugo, G | 1 |
| Cassady, G | 1 |
| Palmisano, P | 1 |
| Teitelbaum, DT | 1 |
| Kier, LC | 1 |
| Jenkins, RB | 1 |
| McCutchen, JJ | 1 |
| Utterback, RA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Transdermal Absorption of DMPS and Its Effect on Urinary Mercury Excretion[NCT01059474] | Phase 1 | 9 participants (Actual) | Interventional | 2010-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for dimercaprol and Arsenic Encephalopathy
| Article | Year |
|---|---|
Treatment of lead and arsenic poisoning in anuric patients - a case report and narrative review of the literature.
Topics: Adult; Animals; Anuria; Arsenic Poisoning; Chelating Agents; Continuous Renal Replacement Therapy; D | 2019 |
Arsenic Toxicity: Molecular Targets and Therapeutic Agents.
Topics: Animals; Antidotes; Arsenic; Arsenic Poisoning; Arsenicals; Chelating Agents; Dimercaprol; Drinking | 2020 |
Biological and environmental hazards associated with exposure to chemical warfare agents: arsenicals.
Topics: Animals; Arsenic Poisoning; Arsenicals; Chemical Warfare; Chemical Warfare Agents; Dimercaprol; Envi | 2016 |
[Practical analysis of toxic substances useful for clinical toxicology--14--arsenics].
Topics: Aged; Arsenic; Arsenic Poisoning; Biomarkers; Blood Transfusion; Chelating Agents; Chromatography, H | 2005 |
Arsenic toxicology: five questions.
Topics: Animals; Arsenic; Arsenic Poisoning; Arsenites; Aryl Hydrocarbon Hydroxylases; Chelating Agents; Cyt | 2006 |
Arsenic induced oxidative stress and the role of antioxidant supplementation during chelation: a review.
Topics: Acetylcysteine; Animals; Antioxidants; Arsenic Poisoning; Ascorbic Acid; Chelating Agents; Chelation | 2007 |
[Molecular mechanism of action of dithiols].
Topics: Animals; Antidotes; Arsenic Poisoning; Chelating Agents; Cholinesterase Inhibitors; Dimercaprol; Dru | 1984 |
DMSA and DMPS--water soluble antidotes for heavy metal poisoning.
Topics: Animals; Antidotes; Arsenic Poisoning; Biotransformation; Cadmium Poisoning; Dimercaprol; Forecastin | 1983 |
Are we ready to replace dimercaprol (BAL) as an arsenic antidote?
Topics: Animals; Antidotes; Arsenic Poisoning; Dimercaprol; Dogs; Guinea Pigs; Humans; Mice; Poisoning; Rats | 1997 |
Survival after massive arsenic poisoning self-treated by high fluid intake.
Topics: Adult; Antidotes; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Dimercaprol; Fluid Therapy; Human | 1998 |
Unanswered questions in metal chelation.
Topics: Animals; Arsenic Poisoning; Chelating Agents; Chelation Therapy; Dimercaprol; Edetic Acid; Humans; L | 1992 |
Poisoning from pesticides: diagnosis and treatment.
Topics: Antidotes; Arsenic Poisoning; Atropine; Carbamates; Child; Cholinesterase Inhibitors; Cholinesterase | 1974 |
105 other studies available for dimercaprol and Arsenic Encephalopathy
| Article | Year |
|---|---|
Diffuse palmoplantar keratotic papules and melanosis.
Topics: Arsenic Poisoning; Arsenicals; Chelating Agents; Child; Dimercaprol; Epilepsy; Humans; Keratoderma, | 2019 |
A Rare Cause of Gastric Injury: Arsenic Intake.
Topics: Arsenic Poisoning; Arsenicals; Burns, Chemical; Chelating Agents; Chlorides; Dimercaprol; Gastric La | 2019 |
Topical efficacy of dimercapto-chelating agents against lewisite-induced skin lesions in SKH-1 hairless mice.
Topics: Administration, Topical; Animals; Arsenic Poisoning; Arsenicals; Chelating Agents; Dermatitis; Dimer | 2013 |
Acute arsenic poisoning diagnosed late.
Topics: Adolescent; Arsenic Poisoning; Chelating Agents; Diagnosis, Differential; Dimercaprol; Humans; Injec | 2016 |
A case of arsical thrombocytopenic purpura treated with BAL.
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Purpura; Purpura, Thrombocytopenic | 1948 |
A case of arsenical dermatitis treated with BAL.
Topics: Arsenic; Arsenic Poisoning; Dermatitis; Dimercaprol | 1948 |
B.A.L. in the treatment of acute arsenic poisoning; a case report.
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Humans | 1948 |
BAL in the treatment of massive overdosage with mapharsen.
Topics: Arsenic; Arsenic Poisoning; Arsenicals; Dimercaprol; Drug Overdose; Humans | 1948 |
A case of arsenic encephalopathy successfully treated with BAL.
Topics: Arsenic; Arsenic Poisoning; Brain Diseases; Dimercaprol | 1948 |
Tryparsamide optic neuritis treated by 2,3 dimercaptopropanol (BAL).
Topics: Arsenic Poisoning; Arsenicals; Dimercaprol; Humans; Neuritis; Optic Neuritis | 1947 |
BAL in the treatment of arsenic ingestion of children.
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Eating; Humans | 1948 |
Treatment of arsenical reaction with BAL.
Topics: Antiprotozoal Agents; Antitrichomonal Agents; Arsenic; Arsenic Poisoning; Dimercaprol; Humans | 1948 |
OX-217 (B.A.L.) as an antidote in complication of arsenic therapy.
Topics: Antidotes; Antiprotozoal Agents; Antitrichomonal Agents; Arsenic; Arsenic Poisoning; Dimercaprol; Hu | 1947 |
BAL, a new remedy for the treatment of poisoning from arsenic and other heavy metals.
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Humans; Poisoning; Poisons | 1947 |
Acute arsenic self-poisoning for suicidal purpose in a dentist: a case report.
Topics: Acute Disease; Aged; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Charcoal; Chelating Agents; Ch | 2009 |
British anti-lewisite; arsenic and thiol excretion in animals after treatment of lewisite burns.
Topics: Animals; Arsenic; Arsenic Poisoning; Arsenicals; Burns; Dimercaprol; Gas Poisoning; Gases; Sulfhydry | 1946 |
The treatment of acute gold and arsenic poisoning; use of BAL (2,3-dimercaptopropanol, British anti-lewisite).
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Gold; Humans | 1947 |
British anti-lewisite; antidotal effects against therapeutic arsenicals.
Topics: Arsenic; Arsenic Poisoning; Arsenicals; Dimercaprol; Humans; Sulfhydryl Compounds | 1947 |
BAL (British anti-lewisite) in the treatment of arsenic and mercury poisoning.
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Humans; Mercury; Mercury Poisoning | 1946 |
Clinical uses of 2,2-dimercaptopropanol (BAL); the systemic treatment of experimental arsenic poisoning (mapharsen, lewisite, phenyl arsenoxide) with BAL.
Topics: Arsenic; Arsenic Poisoning; Arsenicals; Dimercaprol | 1946 |
Clinical uses of 2,3-dimercaptopropanol (BAL); the treatment of lewisite burns of the eye with BAL.
Topics: Arsenic Poisoning; Arsenicals; Burns; Dimercaprol; Eye Injuries; Gas Poisoning | 1946 |
Clinical uses of 2,3-dimercaptopropanol (BAL); the effect of BAL on the excretion of arsenic in arsenical intoxication.
Topics: Arsenic; Arsenic Poisoning; Arsenicals; Biological Transport; Body Fluids; Dimercaprol; Humans | 1946 |
The systemic treatment of arsenic poisoning with BAL (2,3-dimercaptopropanol).
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Humans | 1946 |
2,3 Dithiolpropanol ("BAL") as a specific detoxifying agent for arsenic.
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Humans; Inactivation, Metabolic; Sulfhydryl Compounds | 1946 |
Inadvertent poisoning of seven teenagers with monosodium methanearsonate.
Topics: Accidents, Home; Adolescent; Antidotes; Arsenic Poisoning; Arsenicals; Chelating Agents; Cooking; Di | 2011 |
Toxipathic hepatitis due to Fowler's solution; a case treated with dimercaprol.
Topics: Arsenic; Arsenic Poisoning; Arsenites; Dimercaprol; Hepatitis; Humans; Potassium Compounds | 1953 |
[Arsenical erythroderma; diagnosis of erythrodermas, accidents in arsenical medication, BAL, and present orientation in the treatment of syphilis].
Topics: Accidents; Arsenic Poisoning; Dermatitis, Exfoliative; Dimercaprol; Humans; Syphilis | 1953 |
[Dimercaptropropanol preparations in therapy of arsenic and heavy metal poisoning].
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Heavy Metal Poisoning; Humans; Metals, Heavy; Poisoning | 1953 |
[Case of chiropodal tetraplegia due to subacute lead and arsenic poisoning treated with BAL..].
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Humans; Lead Poisoning; Paralysis; Poisoning; Quadriplegia | 1954 |
Arsenic intoxication.
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Humans; Poisoning | 1954 |
Treatment of arsenic and gold encephalopathy with BAL.
Topics: Arsenic; Arsenic Poisoning; Brain; Brain Diseases; Dimercaprol; Gold; Humans; Poisoning | 1954 |
Peripheral neuropathy caused by arsenical intoxication; a study of 41 cases with observations on the effects of BAL (2, 3, dimercapto-propanol).
Topics: 1-Propanol; Arsenic Poisoning; Dimercaprol; Disease; Humans; Peripheral Nerves; Peripheral Nervous S | 1956 |
[Dermatosis caused by hypersensitivity to arsenic compounds: case report].
Topics: Arsenic Poisoning; Dermatitis; Dermatitis, Contact; Dimercaprol; Drug Eruptions; Humans; Skin Diseas | 1956 |
The pharmacological effects of magnesium arsenate phosphor upon experimental animals.
Topics: Animals; Arsenates; Arsenic Poisoning; Dimercaprol; Magnesium | 1958 |
[Successful treatment of a case of acute severe arsenic poisoning].
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Kidney; Kidneys, Artificial | 1961 |
[A case of reticuloendothelial system reaction to arsenical compounds, with clinical and hematological features of reticulosis, treated with BAL].
Topics: Arsenic Poisoning; Dimercaprol; Humans; Mononuclear Phagocyte System | 1955 |
[Acute arsenic poisoning; treatment with BAL].
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Humans | 1950 |
[Value of B. A. L. in the treatment of arsine poisoning].
Topics: Arsenic Poisoning; Arsenicals; Dimercaprol; Humans | 1951 |
[Value of B. A. L. in the treatment of arsine poisoning].
Topics: Arsenic Poisoning; Arsenicals; Dimercaprol; Humans | 1951 |
[BAL therapy of chronic arsenic poisoning from drinking water].
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Drinking Water; Humans | 1951 |
Use of BAL in the treatment of arsenical neuropathy.
Topics: Arsenic; Arsenic Poisoning; Arsenicals; Dimercaprol; Humans; Neuritis; Peripheral Nervous System Dis | 1951 |
[First applications of BAL in Montevideo in the treatment of arsenic and mercury poisoning].
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Humans; Mercury; Mercury Poisoning | 1950 |
British anti-Lewisite. II. Dithiols as antidotes.
Topics: Antidotes; Arsenic; Arsenic Poisoning; Dimercaprol; Humans; Toluene | 1952 |
British anti-Lewisite. III. Developments and applications.
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Humans | 1952 |
[Arsenical encephalopathy; clinical case cured with BAL, similar case without treatment with fatal outcome].
Topics: Arsenic Poisoning; Brain; Brain Diseases; Dimercaprol; Fatal Outcome; Humans | 1952 |
[Action of dimercapto-2-3-propanol in some arsenic poisonings].
Topics: 1-Propanol; Arsenic; Arsenic Poisoning; Arsenicals; Dimercaprol; Propanols | 1950 |
[A case of neuropathy mimicking Guillain-Barré syndrome after arsenic intoxication].
Topics: Acute Kidney Injury; Arsenic Poisoning; Chelating Agents; Chelation Therapy; Diagnosis, Differential | 2006 |
Successful treatment of potentially fatal heavy metal poisonings.
Topics: Adult; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Chelation Therapy; Decontamination; Dimercap | 2007 |
[Two different clinical cases of acute arsenic trioxide intoxication].
Topics: Adult; Alcoholic Intoxication; Antidotes; Arsenic; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; | 2007 |
Biochemical injury in arsenical intoxication and the British Anti-Lewisite.
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Humans | 1948 |
EI BAL in the treatment of poisoning by arsenical and auric preparations.
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Gold; Gold Compounds; Organogold Compounds | 1949 |
The effect of BAL on experimental lead, tungsten, vanadium, uranium, copper and copper-arsenic poisoning.
Topics: Arsenic; Arsenic Poisoning; Copper; Dimercaprol; Drug-Related Side Effects and Adverse Reactions; He | 1949 |
Arsenic polyneuropathy.
Topics: Adult; Arsenic Poisoning; Dimercaprol; Humans; Male; Nervous System Diseases | 1967 |
Arsenical neuropathy.
Topics: Adult; Aged; Arsenic Poisoning; Dimercaprol; Electrocardiography; Female; Follow-Up Studies; Humans; | 1967 |
Protection of mice against the lethal effects of sodium arsenite by 2,3 dimercapto-1-propane-sulfonic acid and dimercaptosuccinic acid.
Topics: Animals; Arsenic; Arsenic Poisoning; Chelating Agents; Dimercaprol; Disease Models, Animal; Mice; Su | 1980 |
Biological chelation: 2,3-dimercapto-propanesulfonic acid and meso-dimercaptosuccinic acid.
Topics: Animals; Arsenic Poisoning; Arsenites; Cadmium Poisoning; Chelating Agents; Dimercaprol; Lethal Dose | 1982 |
Anti-lewisite activity and stability of meso-dimercaptosuccinic acid and 2,3-dimercapto-1-propanesulfonic acid.
Topics: Administration, Oral; Animals; Arsenic Poisoning; Arsenicals; Dimercaprol; Dose-Response Relationshi | 1982 |
DMSA, DMPS, and DMPA--as arsenic antidotes.
Topics: Animals; Antidotes; Arsenates; Arsenic; Arsenic Poisoning; Arsenicals; Arsenites; Brain; Dimercaprol | 1984 |
Arsenic and copper excretion after treatment of arsenic poisoning in rats with heavy-metal antagonists.
Topics: Animals; Arsenic; Arsenic Poisoning; Chelating Agents; Copper; Dimercaprol; Male; Rats; Rats, Inbred | 1983 |
Optical isomers of 2,3-dimercapto-1-propanesulfonate: antidotal activity, in vitro and in vivo, against sodium arsenite.
Topics: Administration, Oral; Animals; Arsenic Poisoning; Arsenites; Dimercaprol; Injections, Intraperitonea | 1983 |
[Acute arsenic poisoning].
Topics: Acute Disease; Arsenic Poisoning; Dimercaprol; Humans; Male; Middle Aged | 1981 |
Acute lethal arsenite poisoning in mice: effect of treatment with N-acetylcysteine, D-penicillamine and dimercaprol on survival time.
Topics: Acetylcysteine; Animals; Arsenic Poisoning; Dimercaprol; Dose-Response Relationship, Drug; Mice; Pen | 1981 |
The metabolism of arsenic in humans acutely intoxicated by As2O3. Its significance for the duration of BAL therapy.
Topics: Adult; Arsenic; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Child; Dimercaprol; Female; Humans; | 1981 |
Arsenic poisoning.
Topics: Acute Disease; Adolescent; Adult; Arsenates; Arsenic; Arsenic Poisoning; Child, Preschool; Chronic D | 1980 |
Atypical ventricular tachycardia after arsenic poisoning.
Topics: Arsenic Poisoning; Dimercaprol; Humans; Phenytoin; Tachycardia | 1981 |
Effect of various antidotes on the biliary and intestinal excretion of arsenic in situ and into the feces in vivo in guinea-pigs after injection of As2O3.
Topics: Animals; Antidotes; Arsenic; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Bile; Colon; Dimercapr | 1994 |
Reversal of oxophenylarsine-induced inhibition of glucose uptake in MDCK cells.
Topics: Adenosine Triphosphate; Animals; Antidotes; Arsenic Poisoning; Arsenicals; Biological Transport; Cel | 1995 |
Efficacy of dimercapto chelating agents for the treatment of poisoning by percutaneously applied dichloro(2-chlorovinyl)arsine in rabbits.
Topics: Administration, Topical; Animals; Arsenic Poisoning; Arsenicals; Chelating Agents; Chemical and Drug | 1993 |
Isolated rat kidney tubules as a screening system for arsenic antidotes.
Topics: Animals; Antidotes; Arsenates; Arsenic; Arsenic Poisoning; Arsenicals; Arsenites; Chelating Agents; | 1993 |
[Acute arsenic poisoning].
Topics: Accidents, Occupational; Acute Disease; Adult; Arsenic Poisoning; Chelating Agents; Dimercaprol; Hum | 1996 |
Arsenical neuropathy: residual effects following acute industrial exposure.
Topics: Accidents, Occupational; Arsenic Poisoning; Burns, Chemical; Dimercaprol; Environmental Exposure; Hu | 1977 |
The pharmacology of 2,3-dimercaptosuccinic acid and its potential use in arsenic poisoning.
Topics: Animals; Arsenic; Arsenic Poisoning; Dimercaprol; Dogs; Female; Lethal Dose 50; Male; Mice; Minerals | 1978 |
Acute respiratory failure following severe arsenic poisoning.
Topics: Arsenic Poisoning; Dimercaprol; Humans; Male; Middle Aged; Peripheral Nervous System Diseases; Psych | 1979 |
Atempted homicide with arsenic.
Topics: Adult; Arsenic Poisoning; Digestive System; Dimercaprol; Female; Homicide; Humans; Male; Nervous Sys | 1979 |
Therapy of arsenical encephalopathy.
Topics: Arsenic Poisoning; Brain Diseases; Dimercaprol; Humans | 1979 |
[Acute self-poisoning with arsenic and treatment with BAL (author's transl)].
Topics: Arsenic Poisoning; Carbon; Dimercaprol; Female; Gastric Lavage; Humans; Suicide, Attempted | 1978 |
D-penicillamine therapy of acute arsenic poisoning.
Topics: Acute Disease; Arsenic Poisoning; Child, Preschool; Dimercaprol; Humans; Infant; Male; Penicillamine | 1977 |
[Arsenic poisoning in animals].
Topics: Acute Disease; Animals; Antidotes; Arsenic Poisoning; Cattle; Cattle Diseases; Dimercaprol; Drug The | 1976 |
Arsenic poisoning from anti-asthmatic herbal preparations.
Topics: Adolescent; Adult; Arsenic; Arsenic Poisoning; Asthma; Child; Child, Preschool; Dimercaprol; Female; | 1975 |
Test of chelation process to remove arsenic from a biological system using neutron activation.
Topics: Activation Analysis; Arsenic; Arsenic Poisoning; Dimercaprol; Humans; Neutron Activation Analysis; S | 1975 |
Massive arsenic poisoning--effect of hemodialysis and dimercaprol on arsenic kinetics.
Topics: Adult; Arsenic; Arsenic Poisoning; Dimercaprol; Humans; Male; Metabolic Clearance Rate; Poisoning; R | 1992 |
Effect of some arsenic antagonists on the toxicity, distribution and excretion of arsenite and arsenate in rats.
Topics: Animals; Arsenates; Arsenic; Arsenic Poisoning; Arsenites; Dimercaprol; Feces; Male; Metals; Penicil | 1991 |
Massive acute arsenic poisoning.
Topics: Acute Disease; Adult; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Charcoal; Dimercaprol; Fluid | 1991 |
Mass poisoning by sodium arsenite.
Topics: Adolescent; Adult; Argentina; Arsenic; Arsenic Poisoning; Arsenites; Crime; Dimercaprol; Disease Out | 1991 |
Polyneuropathy due to acute arsenic intoxication: biopsy studies.
Topics: Acute Disease; Adult; Arsenic Poisoning; Biopsy; Dimercaprol; Humans; Leg; Male; Microscopy, Electro | 1990 |
Evaluation of the efficacy of dimercapto chelating agents for the treatment of systemic organic arsenic poisoning in rabbits.
Topics: Animals; Arsenic; Arsenic Poisoning; Arsenicals; Body Weight; Chelating Agents; Dimercaprol; Gallbla | 1990 |
Acute lead arsenate poisoning.
Topics: Adult; Aged; Aged, 80 and over; Arsenates; Arsenic Poisoning; Chelation Therapy; Dimercaprol; Edetic | 1989 |
Lack of effectiveness of D-penicillamine in experimental arsenic poisoning.
Topics: Animals; Arsenic; Arsenic Poisoning; Dimercaprol; Guinea Pigs; Male; Mice; Penicillamine; Succimer; | 1989 |
Fatal cardiac arrhythmia in a patient with interstitial myocarditis related to chronic arsenic poisoning.
Topics: Adult; Agricultural Workers' Diseases; Arsenic; Arsenic Poisoning; Chronic Disease; Dimercaprol; Ele | 1989 |
Arsenic excretion after treatment of arsenic poisoning with DMSA or DMPS in mice.
Topics: Animals; Arsenic; Arsenic Poisoning; Dimercaprol; Feces; Male; Mice; Mice, Inbred ICR; Succimer; Sul | 1986 |
Survival following massive arsenic ingestion.
Topics: Adult; Arsenic; Arsenic Poisoning; Dimercaprol; Emergencies; Fluid Therapy; Humans; Male; Naloxone; | 1988 |
An analysis of arsenic exposures referred to the Blodgett Regional Poison Center.
Topics: Arsenic; Arsenic Poisoning; Dimercaprol; Humans; Insecticides; Michigan; Penicillamine; Poison Contr | 1987 |
Endemic chronic arsenism in Xinjiang.
Topics: Adolescent; Adult; Aged; Arsenic; Arsenic Poisoning; Child; China; Dimercaprol; Humans; Keratosis; M | 1985 |
[Unithiol and mecaptid as antidotes in poisoning with arsenic-containing substances].
Topics: Antidotes; Arsenic Poisoning; Dimercaprol; Drug Evaluation; Humans; Sulfhydryl Compounds; Unithiol | 1974 |
British anti-lewisite (BAL), the classic heavy metal antidote.
Topics: Arsenic Poisoning; Arsenicals; Chemistry; Dimercaprol; History, 20th Century; Humans; Lethal Dose 50 | 1972 |
[Recent advance in the therapy of metal poisoning with complexing agents].
Topics: Arsenic Poisoning; Carbon Isotopes; Chelating Agents; Deferoxamine; Dimercaprol; Edetic Acid; Humans | 1972 |
[Chronic arsenic intoxication with atypical involvement of the nervous system].
Topics: Adult; Arsenic; Arsenic Poisoning; Cerebrospinal Fluid Proteins; Chronic Disease; Dimercaprol; Hair; | 1972 |
[Excretion of arsenic in human urine after treatment with BAL].
Topics: Adult; Arsenic; Arsenic Poisoning; Dimercaprol; Humans; Male; Middle Aged; Poisoning; Time Factors | 1973 |
Poisoning due to heavy metals.
Topics: Arsenic Poisoning; Cadmium Poisoning; Chelating Agents; Child; Child, Preschool; Copper; Deferoxamin | 1970 |
Arsenic poisoning in childhood.
Topics: Accidents, Home; Arsenic; Arsenic Poisoning; Blood Chemical Analysis; Child, Preschool; Dimercaprol; | 1970 |
Protein-losing enteropathy associated with arsenic poisoning.
Topics: Administration, Oral; Arsenic; Arsenic Poisoning; Biopsy; Child; Dimercaprol; Edema; Female; Hair; H | 1971 |
Acute maternal arsenic intoxication with neonatal death.
Topics: Acute Kidney Injury; Adolescent; Arsenic; Arsenic Poisoning; Brain; Dimercaprol; Female; Humans; Hya | 1969 |
Arsine poisoning. Report of five cases in the petroleum industry and a discussion of the indications for exchange transfusion and hemodialysis.
Topics: Acute Kidney Injury; Arsenic; Arsenic Poisoning; Arsenicals; Body Weight; Dimercaprol; Environmental | 1969 |
Inorganic arsenic and the nervous system.
Topics: Adolescent; Adult; Aged; Arsenic Poisoning; Child; Child, Preschool; Diagnosis, Differential; Dimerc | 1966 |
Chronic arsenic poisoning resembling muscular dystrophy.
Topics: Arsenic; Arsenic Poisoning; Diagnosis, Differential; Dimercaprol; Hair; Humans; Male; Middle Aged; M | 1966 |