Page last updated: 2024-10-26

dimercaprol and Anemia, Sickle Cell

dimercaprol has been researched along with Anemia, Sickle Cell in 4 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Anemia, Sickle Cell: A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Suarez, CR1
Black, LE1
Hurley, RM1
Nelson, MS1
Chisolm, JJ1
Seeler, RA1
Anku, VD1
Harris, JW1

Other Studies

4 other studies available for dimercaprol and Anemia, Sickle Cell

ArticleYear
Elevated lead levels in a patient with sickle cell disease and inappropriate secretion of antidiuretic hormone.
    Pediatric emergency care, 1992, Volume: 8, Issue:2

    Topics: Anemia, Sickle Cell; Chelation Therapy; Child, Preschool; Dimercaprol; Edetic Acid; Female; Humans;

1992
Lead toxicity masquerading as sickle cell crisis.
    Annals of emergency medicine, 1986, Volume: 15, Issue:6

    Topics: Anemia, Sickle Cell; Child; Diagnostic Errors; Dimercaprol; Edetic Acid; Humans; Lead Poisoning; Mal

1986
Eight children with coexistent sickle cell anemia and plumbism.
    Clinical pediatrics, 1974, Volume: 13, Issue:6

    Topics: Anemia, Sickle Cell; Blood Transfusion; Chelating Agents; Dimercaprol; Edetic Acid; Female; Glucosep

1974
Peripheral neuropathy and lead poisoning in a child with sickle-cell anemia. Case report and review of the literature.
    The Journal of pediatrics, 1974, Volume: 85, Issue:3

    Topics: Anemia, Sickle Cell; Blood Urea Nitrogen; Calcium; Child; Diagnosis, Differential; Dimercaprol; Edet

1974