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dimercaprol and Anemia, Hypoplastic

dimercaprol has been researched along with Anemia, Hypoplastic in 8 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Research Excerpts

ExcerptRelevanceReference
"Three patients receiving gold salt treatment for rheumatoid arthritis developed severe aplastic anemia."1.27Gold-induced aplastic anemia. ( Immesoete, C; Joos, R; Proot, F; Williame, LM, 1987)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BOWER, JS1
WATSON, EM1
INDYK, JS1
BASTRUP-MADSEN, P1
Gorokhovskaia, GN1
Kozhurin, SV1
Fedotenkov, SA1
Omel'ianenko, NM1
Kriuchkova, LS1
Williame, LM1
Joos, R1
Proot, F1
Immesoete, C1
Ganzoni, A1
Böhni, P1

Other Studies

8 other studies available for dimercaprol and Anemia, Hypoplastic

ArticleYear
Aplastic anemia due to gold therapy unsuccessfully treated with BAL.
    North Carolina medical journal, 1952, Volume: 13, Issue:7

    Topics: Anemia; Anemia, Aplastic; Dimercaprol; Gold; Humans; North Carolina

1952
The haematopathological complications of gold therapy: effects of splenectomy and bal.
    Canadian Medical Association journal, 1953, Volume: 69, Issue:1

    Topics: Anemia; Anemia, Aplastic; Arthritis; Arthritis, Rheumatoid; Dimercaprol; Gold; Humans; Purpura; Purp

1953
A case of aplastic anaemia due to gold therapy treated with BAL.
    The Medical journal of Australia, 1949, Jul-02, Volume: 2, Issue:1

    Topics: Anemia, Aplastic; Dimercaprol; Gold; Gold Compounds; Organogold Compounds

1949
Late Cases Of Aplastic Anemia Following Sanocrysin Treatment; Treatment With B.A.L. (2.3-Dimercapto Propanol)
    Ugeskrift for laeger, 1949, Apr-07, Volume: 111, Issue:14

    Topics: Anemia; Anemia, Aplastic; Dimercaprol; Gold; Gold Compounds; Gold Sodium Thiosulfate; Humans; Organo

1949
[Complications of the treatment of rheumatoid arthritis with chrysanol].
    Sovetskaia meditsina, 1989, Issue:8

    Topics: Anemia, Aplastic; Antirheumatic Agents; Arthritis, Rheumatoid; Dimercaprol; Female; Humans; Metallop

1989
Gold-induced aplastic anemia.
    Clinical rheumatology, 1987, Volume: 6, Issue:4

    Topics: Adult; Aged; Anemia, Aplastic; Arthritis, Rheumatoid; Dimercaprol; Female; Humans; Metalloproteins;

1987
Treatment of lead poisoning.
    The Medical letter on drugs and therapeutics, 1972, Feb-04, Volume: 14, Issue:3

    Topics: Administration, Oral; Adult; Anemia, Aplastic; Chelating Agents; Child; Dimercaprol; Edetic Acid; En

1972
[Panmyelopathy following gold therapy of primary chronic polyarthritis. Pathogenetic aspects of gold damage].
    Schweizerische medizinische Wochenschrift, 1965, Oct-16, Volume: 95, Issue:42

    Topics: Anemia, Aplastic; Arthritis, Rheumatoid; Bone Marrow Examination; Cortisone; Dimercaprol; Drug Hyper

1965