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dimercaprol and Amyloidosis

dimercaprol has been researched along with Amyloidosis in 3 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Amyloidosis: A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits.

Research Excerpts

ExcerptRelevanceReference
"Seventy-five patients with secondary amyloidosis were treated with unithiol."7.67[Unithiol in the treatment of secondary amyloidosis patients]. ( Postnikov, AV, 1984)
"Seventy-five patients with secondary amyloidosis were treated with unithiol."3.67[Unithiol in the treatment of secondary amyloidosis patients]. ( Postnikov, AV, 1984)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Postnikov, AV3
Dubinskiĭ, AA1
Bondarenko, IP1
Iakovtsova, AF1
Liss, ND1
Roslik, SM1

Other Studies

3 other studies available for dimercaprol and Amyloidosis

ArticleYear
[Unithiol in the treatment of secondary amyloidosis patients].
    Terapevticheskii arkhiv, 1984, Volume: 56, Issue:10

    Topics: Amyloidosis; Dimercaprol; Drug Evaluation; Humans; Injections, Intramuscular; Unithiol

1984
[Unithiol therapy of patients with secondary amyloidosis (preliminary report)].
    Terapevticheskii arkhiv, 1980, Volume: 52, Issue:8

    Topics: Amyloidosis; Dimercaprol; Humans; Unithiol

1980
[Use of unithiol in complex treatment of tuberculosis complicated by secondary amyloidosis].
    Problemy tuberkuleza, 1980, Issue:3

    Topics: Amyloidosis; Antitubercular Agents; Dimercaprol; Humans; Tuberculosis, Pulmonary; Unithiol

1980