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dimercaprol and Alopecia Cicatrisata

dimercaprol has been researched along with Alopecia Cicatrisata in 2 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Research Excerpts

ExcerptRelevanceReference
"In the German Federal Republic it has recently become known that generalised disorders of chronic mercury poisoning (loss of weight, stomatitis, hearing and sensory loss, emotional disturbances) have accompanied the cardinal signs of nail discolouration and loss of hair."7.65[Nail changes and loss of hair: cardinal signs of mercury poisoning from hair bleaches (author's transl)]. ( Herpers, H; Käferstein, H; Orfanos, CE; Steinbach, H; Wüstner, H, 1975)
"In the German Federal Republic it has recently become known that generalised disorders of chronic mercury poisoning (loss of weight, stomatitis, hearing and sensory loss, emotional disturbances) have accompanied the cardinal signs of nail discolouration and loss of hair."3.65[Nail changes and loss of hair: cardinal signs of mercury poisoning from hair bleaches (author's transl)]. ( Herpers, H; Käferstein, H; Orfanos, CE; Steinbach, H; Wüstner, H, 1975)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GRUNFELD, O1
HINOSTROZA, G1
Wüstner, H1
Orfanos, CE1
Steinbach, H1
Käferstein, H1
Herpers, H1

Other Studies

2 other studies available for dimercaprol and Alopecia Cicatrisata

ArticleYear
THALLIUM POISONING.
    Archives of internal medicine, 1964, Volume: 114

    Topics: Adolescent; Alopecia; Dimercaprol; Drug Therapy; Gastroenterology; Heavy Metal Poisoning; Metals, He

1964
[Nail changes and loss of hair: cardinal signs of mercury poisoning from hair bleaches (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1975, Aug-22, Volume: 100, Issue:34

    Topics: Alopecia; Chronic Disease; Cosmetics; Dimercaprol; Female; Humans; Mercury; Mercury Poisoning; Middl

1975