Page last updated: 2024-10-26

dimercaprol and Alkalosis

dimercaprol has been researched along with Alkalosis in 1 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Alkalosis: A pathological condition that removes acid or adds base to the body fluids.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Littman, E1
Goldstein, MH1
Kasen, L1
Levitt, MF1
Wedeen, RP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Treatment of Lead-Exposed Children (TLC) Trial[NCT00342849]Phase 3780 participants (Actual)Interventional1994-07-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for dimercaprol and Alkalosis

ArticleYear
The relationship of the intrarenal distribution of Hg203-chlormerodrin to the diuretic effect.
    The Journal of pharmacology and experimental therapeutics, 1966, Volume: 152, Issue:1

    Topics: Acidosis; Alkalosis; Animals; Autoradiography; Chlormerodrin; Chloromercuribenzoates; Dimercaprol; D

1966