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dimercaprol and Agranulocytosis

dimercaprol has been researched along with Agranulocytosis in 3 studies

Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.

Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HOLLEY, HL1
BENDER, CE1
HOXSEY, RJ1
DeMARSH, QB1
COSTE, F1
GALMICHE, P1

Other Studies

3 other studies available for dimercaprol and Agranulocytosis

ArticleYear
The use of BAL (2,3-dimercaptopropanol) in the treatment of agranulocytosis following intensive arsenotherapy for syphilis.
    Annals of internal medicine, 1947, Volume: 27, Issue:2

    Topics: Agranulocytosis; Arsenic; Dimercaprol; Syphilis

1947
Neutropenia in a patient treated with a mercurial diuretic and its response to BAL.
    Annals of internal medicine, 1950, Volume: 33, Issue:5

    Topics: Agranulocytosis; Dimercaprol; Diuretics; Mercury; Neutropenia; Organomercury Compounds

1950
Auric agranulocytosis treated only by the B.A.L .; healing.
    Revue du rhumatisme et des maladies osteo-articulaires, 1949, Volume: 16, Issue:5

    Topics: Agranulocytosis; Dimercaprol

1949