dimercaprol has been researched along with Aging in 2 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (50.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Subra, JF | 1 |
Cautain, B | 1 |
Xystrakis, E | 1 |
Mas, M | 1 |
Lagrange, D | 1 |
van der Heijden, H | 1 |
van de Gaar, MJ | 1 |
Druet, P | 1 |
FourniƩ, GJ | 1 |
Saoudi, A | 1 |
Damoiseaux, J | 1 |
Bakshy, S | 1 |
Gershbein, LL | 1 |
2 other studies available for dimercaprol and Aging
Article | Year |
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The balance between CD45RChigh and CD45RClow CD4 T cells in rats is intrinsic to bone marrow-derived cells and is genetically controlled.
Topics: Aging; Animals; Bone Marrow Cells; CD4-Positive T-Lymphocytes; Cells, Cultured; Cytokines; Dimercapr | 2001 |
In vivo depression of hepatic succinoxidase by sulfhydryl compounds.
Topics: Aging; Animals; Castration; Depression, Chemical; Dihydrolipoamide Dehydrogenase; Dimercaprol; Elect | 1971 |