dimercaprol has been researched along with African Sleeping Sickness in 8 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ROBERTSON, DH | 2 |
| CAHILL, KM | 1 |
| WALLS, LP | 1 |
| Siguier, F | 1 |
| Betourne, C | 1 |
| Lanza, M | 1 |
| Herreman, G | 1 |
| Piette, F | 1 |
| Jennings, FW | 1 |
| Atouguia, JM | 1 |
| Murray, M | 1 |
| Hamon, JF | 1 |
| Seri, B | 1 |
| Doua, F | 1 |
| Camara, P | 1 |
| Aba, L | 1 |
| Scena, MR | 1 |
1 review available for dimercaprol and African Sleeping Sickness
| Article | Year |
|---|---|
THE CHEMOTHERAPY OF TRYPANOSOMIASIS.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antimony; Antiprotozoal Agents; Arsenic | 1963 |
7 other studies available for dimercaprol and African Sleeping Sickness
| Article | Year |
|---|---|
The treatment of sleeping sickness (mainly due to Trypanosoma rhodesiense) with melarsoprol. I. Reactions observed during treatment.
Topics: Animals; Arsenicals; Dimercaprol; Humans; Melarsoprol; Trypanosoma brucei rhodesiense; Trypanosomias | 1963 |
The treatment of sleeping sickness (mainly due to Trypanosoma rhodesiense) with melarsoprol.
Topics: Animals; Arsenicals; Dimercaprol; Humans; Melarsoprol; Trypanosoma brucei rhodesiense; Trypanosomias | 1963 |
THE HUMAN TRYPANOSOMATIDAE. I.
Topics: Amidines; Animals; Dimercaprol; Humans; Pathology; Suramin; Trypanosomatina; Trypanosomiasis; Trypan | 1963 |
[Trypanosomal meningo-encephalitis observed in France. Reflections concerning the use of arsobal].
Topics: Adult; Antiprotozoal Agents; Arsenicals; Dimercaprol; Female; Glucocorticoids; Humans; Trypanosomias | 1967 |
The importance of 2,3-dimercaptopropinol (British anti-lewisite, BAL) in the trypanocidal activity of topical melarsoprol.
Topics: Administration, Topical; Animals; Arsenicals; Dimercaprol; Drug Combinations; Female; Gels; Melarsop | 1996 |
Effects of Mel B arsobal and alpha-difluoromethylornithine on the awakening electroencephalogram of humans with gambiense trypanosomiasis disease: preliminary report.
Topics: Adolescent; Adult; Arsenicals; Dimercaprol; Drug Combinations; Eflornithine; Electroencephalography; | 1990 |
Melarsoprol toxicity in the treatment of human African trypanosomiasis. Ten cases treated with dimercaprol.
Topics: Adolescent; Adult; Arsenicals; Central Nervous System Diseases; Dimercaprol; Female; Humans; Male; M | 1988 |