dimercaprol has been researched along with Acute Kidney Injury in 20 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The renal tubular necrosis and calcification as well as the mortality induced by mercuric chloride in the rat are readily prevented by prior treatment with well-tolerated amounts of spironolactone." | 7.65 | Mercury poisoning: prevention by spironolactone. ( Selye, H, 1970) |
| "Although treatment has been well defined for childhood lead poisoning and for industrial lead exposure, the treatment of lead nephropathy has been poorly studied." | 3.65 | Chelation therapy in lead nephropathy. ( Morgan, JM, 1975) |
| "The renal tubular necrosis and calcification as well as the mortality induced by mercuric chloride in the rat are readily prevented by prior treatment with well-tolerated amounts of spironolactone." | 3.65 | Mercury poisoning: prevention by spironolactone. ( Selye, H, 1970) |
| "Acute arsenic poisoning is less frequent and it is most often lethal." | 1.33 | [A case of neuropathy mimicking Guillain-Barré syndrome after arsenic intoxication]. ( Defebvre, L; Destee, A; Devos, D; Hurtevent, JF; Perriol, MP; Saulnier, F; Tiffreau, V, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (80.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hassan, S | 1 |
| Shaikh, MU | 1 |
| Ali, N | 1 |
| Riaz, M | 1 |
| DOOLAN, PD | 1 |
| HESS, WC | 1 |
| KYLE, LH | 1 |
| SANCHEZ-SICILIA, L | 1 |
| SETO, DS | 1 |
| NAKAMOTO, S | 1 |
| KOLFF, WJ | 1 |
| SITBON, A | 1 |
| VALEK, A | 1 |
| Perriol, MP | 1 |
| Devos, D | 1 |
| Hurtevent, JF | 1 |
| Tiffreau, V | 1 |
| Saulnier, F | 1 |
| Destee, A | 1 |
| Defebvre, L | 1 |
| Mitchell, WM | 1 |
| Basinger, MA | 1 |
| Jones, MM | 1 |
| Debray, P | 1 |
| Besson-Leaud, M | 1 |
| Lavaud, J | 1 |
| Mselati, JC | 1 |
| Quattrocchi, F | 1 |
| Cloup, M | 1 |
| Morgan, JM | 1 |
| Stevens, E | 2 |
| Ectors, M | 2 |
| Cornil, A | 2 |
| Damrau, J | 1 |
| Aguado, S | 1 |
| de Quirós, IF | 1 |
| Marín, R | 1 |
| Gago, E | 1 |
| Gómez, E | 1 |
| Fernández-Vega, F | 1 |
| Alvarez Grande, J | 1 |
| Ganeval, D | 1 |
| Lachand, AT | 1 |
| Kleinknecht, D | 1 |
| Jungers, P | 1 |
| Lowenthal, DT | 1 |
| Chardo, F | 1 |
| Reidenberg, MM | 1 |
| Witzgall, H | 1 |
| Chisolm, JJ | 1 |
| Selye, H | 1 |
| Lugo, G | 1 |
| Cassady, G | 1 |
| Palmisano, P | 1 |
| Teitelbaum, DT | 1 |
| Kier, LC | 1 |
20 other studies available for dimercaprol and Acute Kidney Injury
| Article | Year |
|---|---|
Copper sulphate toxicity in a young male complicated by methemoglobinemia, rhabdomyolysis and renal failure.
Topics: Acute Kidney Injury; Chelating Agents; Copper Sulfate; Dimercaprol; Humans; Male; Methemoglobinemia; | 2010 |
Acute renal insufficiency due to bichloride of mercury; observations on gastrointestinal hemorrhage and BAL therapy.
Topics: Acute Kidney Injury; Dimercaprol; Gastrointestinal Hemorrhage; Gastrointestinal Tract; Hemorrhage; H | 1953 |
ACUTE MERCURIAL INTOXICATION TREATED BY HEMODIALYSIS.
Topics: Acute Kidney Injury; Dimercaprol; Infusions, Parenteral; Kidney; Kidneys, Artificial; Mercury Poison | 1963 |
[RENAL INVOLVEMENT DURING ACUTE POISONINGS].
Topics: Acute Kidney Injury; Dimercaprol; Kidney; Kidneys, Artificial; Poisoning; Renal Insufficiency; Thiom | 1964 |
ACUTE RENAL INSUFFICIENCY IN INTOXICATIONS WITH MERCURY COMPOUNDS. II. TREATMENT AND PROGNOSIS.
Topics: Acute Kidney Injury; Antidotes; Anuria; Dimercaprol; Gastric Lavage; Kidneys, Artificial; Mercury Co | 1965 |
[A case of neuropathy mimicking Guillain-Barré syndrome after arsenic intoxication].
Topics: Acute Kidney Injury; Arsenic Poisoning; Chelating Agents; Chelation Therapy; Diagnosis, Differential | 2006 |
Antagonism of acute copper(II)-induced renal lesions by sodium 2,3-dimercaptopropanesulfonate.
Topics: Acute Kidney Injury; Animals; Copper; Copper Sulfate; Dimercaprol; Kidney; Kidney Tubular Necrosis, | 1982 |
[Acute mercury poisoning in children (author's transl)].
Topics: Acute Disease; Acute Kidney Injury; Child; Child, Preschool; Dimercaprol; Female; Humans; Infant, Ne | 1979 |
Chelation therapy in lead nephropathy.
Topics: Acute Kidney Injury; Administration, Oral; Chelating Agents; Creatinine; Dimercaprol; Drug Eruptions | 1975 |
Acute intoxication by ingestion of inorganic mercury salts.
Topics: Acute Kidney Injury; Adult; Chelating Agents; Cyanides; Dimercaprol; Disinfectants; Female; Humans; | 1990 |
[Treatment of mercury-induced organ damage].
Topics: Acute Kidney Injury; Adult; Dimercaprol; Drug Therapy, Combination; Humans; Indomethacin; Kidney Fun | 1990 |
Acute mercury vapour intoxication: report of six cases.
Topics: Acute Disease; Acute Kidney Injury; Adult; Dimercaprol; Humans; Male; Mercury Poisoning; Middle Aged | 1989 |
[Case of acute poisoning by mercuric oxycyanide].
Topics: Acute Kidney Injury; Adult; Cyanides; Dimercaprol; Female; Humans; Mercury; Mercury Compounds; Mercu | 1989 |
[Acute mercury poisoning after bladder lavage using mercury oxycyanide (3 cases)].
Topics: Acute Kidney Injury; Aged; Anti-Infective Agents, Urinary; Anuria; Blindness; Cyanides; Diarrhea; Di | 1973 |
Removal of mercury by peritoneal dialysis.
Topics: Acute Kidney Injury; Adult; Dimercaprol; Humans; Injections, Intramuscular; Male; Mercury Poisoning; | 1974 |
[Gold therapy in chronic joint rheumatism].
Topics: Acute Kidney Injury; Arthritis, Rheumatoid; Dimercaprol; Drug Hypersensitivity; Gold; Hematologic Di | 1967 |
Treatment of acute lead intoxication--choice of chelating agents and supportive therapeutic measures.
Topics: Acute Kidney Injury; Chelating Agents; Dimercaprol; Edetic Acid; Environmental Exposure; Humans; Lea | 1970 |
Mercury poisoning: prevention by spironolactone.
Topics: Acute Kidney Injury; Animals; Chelating Agents; Dimercaprol; Female; Kidney Tubules; Mercury Poisoni | 1970 |
Acute maternal arsenic intoxication with neonatal death.
Topics: Acute Kidney Injury; Adolescent; Arsenic; Arsenic Poisoning; Brain; Dimercaprol; Female; Humans; Hya | 1969 |
Arsine poisoning. Report of five cases in the petroleum industry and a discussion of the indications for exchange transfusion and hemodialysis.
Topics: Acute Kidney Injury; Arsenic; Arsenic Poisoning; Arsenicals; Body Weight; Dimercaprol; Environmental | 1969 |