dimercaprol has been researched along with Acute Disease in 33 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
Acute Disease: Disease having a short and relatively severe course.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of self-poisoning with sodium selenate sheep drench, along with blood and urine levels of selenium, is reported." | 7.66 | Acute selenium poisoning: case report. ( Civil, ID; McDonald, MJ, 1978) |
| "A case of self-poisoning with sodium selenate sheep drench, along with blood and urine levels of selenium, is reported." | 3.66 | Acute selenium poisoning: case report. ( Civil, ID; McDonald, MJ, 1978) |
| "We report three cases of arsenic poisoning in a chemical factory." | 1.29 | [Acute arsenic poisoning]. ( Abildtrup, A; Ebbehøj, NE; Eshøj, O; Johansen, JB; Kristensen, SR, 1996) |
| "Treatment with dimercaprol remains the mainstay of therapy, and early treatment is necessary to prevent irreversible complications." | 1.26 | Arsenic poisoning. ( Schoolmeester, WL; White, DR, 1980) |
| "The use of D-penicillamine in arsenic poisoning has not been generally appreciated." | 1.26 | D-penicillamine therapy of acute arsenic poisoning. ( Peterson, RG; Rumack, BH, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (75.76) | 18.7374 |
| 1990's | 5 (15.15) | 18.2507 |
| 2000's | 3 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yilmaz, Y | 1 |
| Armagan, E | 1 |
| Olmez, O | 1 |
| Esen, M | 1 |
| Alkis, N | 1 |
| Dolar, E | 1 |
| LAMBIC, IC | 1 |
| LEVNTAL, Z | 1 |
| RITTEY, DA | 1 |
| Ellis, EN | 1 |
| Brouhard, BH | 1 |
| Lynch, RE | 1 |
| Dawson, EB | 1 |
| Tisdell, R | 1 |
| Nichols, MM | 1 |
| Ramirez, F | 1 |
| Christensen, P | 1 |
| Frost, JW | 1 |
| Søjbjerg, JO | 1 |
| Schoolmeester, WL | 1 |
| White, DR | 1 |
| McKinney, PE | 1 |
| Brent, J | 1 |
| Kulig, K | 1 |
| Johansen, JB | 1 |
| Abildtrup, A | 1 |
| Ebbehøj, NE | 1 |
| Kristensen, SR | 1 |
| Eshøj, O | 1 |
| De Groote, WJ | 1 |
| Sabbe, MB | 1 |
| Meulemans, AI | 1 |
| Desmet, KJ | 1 |
| Delooz, HH | 1 |
| Ozuah, PO | 1 |
| Takeda, T | 1 |
| Yukioka, T | 1 |
| Shimazaki, S | 1 |
| Debray, P | 1 |
| Besson-Leaud, M | 1 |
| Lavaud, J | 1 |
| Mselati, JC | 1 |
| Quattrocchi, F | 1 |
| Cloup, M | 1 |
| Chisolm, JJ | 2 |
| Barltrop, D | 1 |
| Jones, MM | 1 |
| Basinger, MA | 1 |
| Civil, ID | 1 |
| McDonald, MJ | 1 |
| Shakhnazarov, AM | 1 |
| Pocheptsov, VG | 1 |
| Shaposhnikova, LB | 1 |
| Walsh, FM | 1 |
| Crosson, FJ | 1 |
| Bayley, M | 1 |
| McReynolds, J | 1 |
| Pearson, BJ | 1 |
| Peterson, RG | 1 |
| Rumack, BH | 1 |
| Balatskiĭ, KP | 1 |
| Hofmann, U | 1 |
| Segewitz, G | 1 |
| Jolliffe, DM | 1 |
| Budd, AJ | 1 |
| Gwilt, DJ | 1 |
| Goebel, HH | 1 |
| Schmidt, PF | 1 |
| Bohl, J | 1 |
| Tettenborn, B | 1 |
| Krämer, G | 1 |
| Gutmann, L | 1 |
| Aguado, S | 1 |
| de Quirós, IF | 1 |
| Marín, R | 1 |
| Gago, E | 1 |
| Gómez, E | 1 |
| Fernández-Vega, F | 1 |
| Alvarez Grande, J | 1 |
| Ivanov, N | 1 |
| Zheliazkov, D | 1 |
| Mangŭrova, M | 1 |
| Belcheva, A | 1 |
| Kalitsin, I | 1 |
| Henderson, P | 1 |
| Hale, TW | 1 |
| Shum, S | 1 |
| Habersang, RW | 1 |
| Trux, F | 1 |
| Grossmann, K | 1 |
| Giegler, I | 1 |
| Spellberg, MA | 1 |
| Sundwall, A | 1 |
| Werner, B | 1 |
| Czarnecki, J | 1 |
| Kawiak, W | 1 |
| Nowakowski, A | 1 |
| Kaufman, DB | 1 |
| DiNicola, W | 1 |
| McIntosh, R | 1 |
4 reviews available for dimercaprol and Acute Disease
| Article | Year |
|---|---|
Mercury poisoning.
Topics: Acute Disease; Chelating Agents; Chelation Therapy; Child; Diagnosis, Differential; Dimercaprol; Env | 2000 |
Recognition and management of children with increased lead absorption.
Topics: Absorption; Acute Disease; Behavior; Bone and Bones; Bone Marrow; Brain Diseases; Child; Dimercaprol | 1979 |
The use of chelating agents in the treatment of acute and chronic lead intoxication in childhood.
Topics: Acute Disease; Amino Acids; Animals; Brain Diseases; Child; Child, Preschool; Chronic Disease; Creat | 1968 |
Treatment of hepatolenticular degeneration. (Wilson's disease).
Topics: Acute Disease; Ceruloplasmin; Copper; Diet Therapy; Dimercaprol; Edetic Acid; Ethinyl Estradiol; Hep | 1969 |
29 other studies available for dimercaprol and Acute Disease
| Article | Year |
|---|---|
Acute arsenic self-poisoning for suicidal purpose in a dentist: a case report.
Topics: Acute Disease; Aged; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Charcoal; Chelating Agents; Ch | 2009 |
[First experiences in therapy of acute hepatitis with BAL..].
Topics: Acute Disease; Dimercaprol; Hepatitis; Hepatitis A | 1953 |
Dimercaprol in acute antimony dermatitis.
Topics: Acute Disease; Antimony; Dermatitis; Dimercaprol; Humans | 1950 |
Effects of hemodialysis and dimercaprol in acute dichromate poisoning.
Topics: Acute Disease; Animals; Chromates; Dimercaprol; Dogs; Humans; Infant; Male; Metabolic Clearance Rate | 1982 |
[Acute arsenic poisoning].
Topics: Acute Disease; Arsenic Poisoning; Dimercaprol; Humans; Male; Middle Aged | 1981 |
Arsenic poisoning.
Topics: Acute Disease; Adolescent; Adult; Arsenates; Arsenic; Arsenic Poisoning; Child, Preschool; Chronic D | 1980 |
Acute zinc chloride ingestion in a child: local and systemic effects.
Topics: Acidosis; Acute Disease; Ammonium Chloride; Amylases; Burns, Chemical; Chemical and Drug Induced Liv | 1994 |
[Acute arsenic poisoning].
Topics: Accidents, Occupational; Acute Disease; Adult; Arsenic Poisoning; Chelating Agents; Dimercaprol; Hum | 1996 |
An acute zinc chloride poisoning in a child: was chelator therapy effective?
Topics: Acute Disease; Chelating Agents; Chlorides; Dimercaprol; Humans; Infant; Male; Zinc Compounds | 1998 |
Cupric sulfate intoxication with rhabdomyolysis, treated with chelating agents and blood purification.
Topics: Acute Disease; Adolescent; Chelating Agents; Copper Sulfate; Dimercaprol; Drug Therapy, Combination; | 2000 |
[Acute mercury poisoning in children (author's transl)].
Topics: Acute Disease; Acute Kidney Injury; Child; Child, Preschool; Dimercaprol; Female; Humans; Infant, Ne | 1979 |
Restrictions on the applicability of mixed ligand chelate therapy (MLC) in acute cadmium intoxication.
Topics: Acute Disease; Animals; Cadmium Poisoning; Chelating Agents; Dimercaprol; Drug Therapy, Combination; | 1979 |
Acute selenium poisoning: case report.
Topics: Acute Disease; Adolescent; Ascorbic Acid; Dimercaprol; Female; Humans; Poisoning; Selenium | 1978 |
[Effectiveness of using unithiol in combination with ephedrine in acute enteral poisoning with sodium bichromate].
Topics: Acute Disease; Animals; Chromates; Dimercaprol; Drug Evaluation, Preclinical; Ephedrine; Rats; Sodiu | 1978 |
[Case of ventricular tachysystole treated with unithiol].
Topics: Acute Disease; Dimercaprol; Heart Ventricles; Humans; Male; Middle Aged; Myocardial Infarction; Tach | 1978 |
Acute copper intoxication. Pathophysiology and therapy with a case report.
Topics: Acute Disease; Anemia, Hemolytic; Copper; Dimercaprol; Humans; Infant; Kidney Tubular Necrosis, Acut | 1977 |
D-penicillamine therapy of acute arsenic poisoning.
Topics: Acute Disease; Arsenic Poisoning; Child, Preschool; Dimercaprol; Humans; Infant; Male; Penicillamine | 1977 |
[Arsenic poisoning in animals].
Topics: Acute Disease; Animals; Antidotes; Arsenic Poisoning; Cattle; Cattle Diseases; Dimercaprol; Drug The | 1976 |
Influence of chelation therapy on acute lead intoxication in rats.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Body Weight; Bone and Bones; Chelating Agents; Dimercap | 1975 |
Massive acute arsenic poisoning.
Topics: Acute Disease; Adult; Arsenic Poisoning; Arsenic Trioxide; Arsenicals; Charcoal; Dimercaprol; Fluid | 1991 |
Polyneuropathy due to acute arsenic intoxication: biopsy studies.
Topics: Acute Disease; Adult; Arsenic Poisoning; Biopsy; Dimercaprol; Humans; Leg; Male; Microscopy, Electro | 1990 |
Acute mercury vapour intoxication: report of six cases.
Topics: Acute Disease; Acute Kidney Injury; Adult; Dimercaprol; Humans; Male; Mercury Poisoning; Middle Aged | 1989 |
[Organ-dependent sulfhydryl group reduction in acute mercury poisoning and the effects of mono- and dithiol antidotes and the protein hydrolysate Khidroprot].
Topics: Acute Disease; Animals; Antidotes; Dimercaprol; Drug Evaluation, Preclinical; Male; Mercury Poisonin | 1985 |
N-Acetylcysteine therapy of acute heavy metal poisoning in mice.
Topics: Acetylcysteine; Acute Disease; Animals; Dimercaprol; Metals; Mice; Penicillamine | 1985 |
[Acute intermittent porphyria (our personal observations in a family)].
Topics: Acute Disease; Adrenocorticotropic Hormone; Adult; Biopsy; Chlorpromazine; Cytochromes; Dimercaprol; | 1971 |
[Treatment of acute poisoning. 4. Treatment with specific antidotes].
Topics: Acute Disease; Animals; Antidotes; Atropine; Chelating Agents; Dimercaprol; Edetic Acid; Humans; Lev | 1971 |
[Treatment of acute poisoning. 5. The experience of the poisoning information center with poisonings--specifically pediatric aspects].
Topics: Acute Disease; Antidotes; Charcoal; Child, Preschool; Copper; Dimercaprol; Edetic Acid; Humans; Myco | 1971 |
[A case of acute intermittent porphyria].
Topics: Abdomen, Acute; Acute Disease; Adult; Diagnosis, Differential; Dimercaprol; Humans; Male; Porphyrias | 1969 |
Acute potassium dichromate poisoning. Treated by peritoneal dialysis.
Topics: Acute Disease; Adolescent; Ascorbic Acid; Autopsy; Brain Chemistry; Chromates; Chromium; Dimercaprol | 1970 |