dimercaprol has been researched along with Acidosis in 2 studies
Dimercaprol: An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning.
dimercaprol : A dithiol that is propane-1,2-dithiol in which one of the methyl hydrogens is replaced by a hydroxy group. a chelating agent originally developed during World War II as an experimental antidote against the arsenic-based poison gas Lewisite, it has been used clinically since 1949 for the treatment of poisoning by arsenic, mercury and gold. It can also be used for treatment of poisoning by antimony, bismuth and possibly thallium, and (with sodium calcium edetate) in cases of acute leaad poisoning. Administration is by (painful) intramuscular injection of a suspension of dimercaprol in peanut oil, typically every 4 hours for 2-10 days depending on the toxicity. In the past, dimercaprol was also used for the treatment of Wilson's disease, a severely debilitating genetic disorder in which the body tends to retain copper, with resultant liver and brain injury.
Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McKinney, PE | 1 |
| Brent, J | 1 |
| Kulig, K | 1 |
| Littman, E | 1 |
| Goldstein, MH | 1 |
| Kasen, L | 1 |
| Levitt, MF | 1 |
| Wedeen, RP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Lead-Exposed Children (TLC) Trial[NCT00342849] | Phase 3 | 780 participants (Actual) | Interventional | 1994-07-15 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for dimercaprol and Acidosis
| Article | Year |
|---|---|
Acute zinc chloride ingestion in a child: local and systemic effects.
Topics: Acidosis; Acute Disease; Ammonium Chloride; Amylases; Burns, Chemical; Chemical and Drug Induced Liv | 1994 |
The relationship of the intrarenal distribution of Hg203-chlormerodrin to the diuretic effect.
Topics: Acidosis; Alkalosis; Animals; Autoradiography; Chlormerodrin; Chloromercuribenzoates; Dimercaprol; D | 1966 |